Abstract: A method for computer-aided plate punching is disclosed. The method includes the steps of reading and configuring processing data; reading a design drawing of a workpiece as a processing diagram; selecting needed figures from the processing diagram, and configuring template attributes to confirm contour of the workpiece; selecting operation modes and cutters for processing orifices; processing the orifices and generating cutters information; selecting operation modes and cutters for processing slots; processing the slots and generating cutters information; optimizing the cutters information, and generating a list of cutters; and converting the list of cutters into corresponding CNC codes. A related system is also disclosed.