Abstract: Linker-drug compounds and antibody-drug conjugates that bind to human oncology targets are disclosed. The linker-drug compounds and antibody-drug conjugates comprise a splicing modulator drug moiety. The disclosure further relates to methods and compositions for use in the treatment of neoplastic disorders by administering the antibody-drug conjugates provided herein. In an embodiment, the splicing modulator comprises a pladienolide or a pladienolide derivative.

Abstract: A banknote stacking and separating apparatus and a banknote processing apparatus relate to automated machinery. The banknote stacking and separating apparatus includes a frame, and a guide plate and a pressing plate that are disposed on the frame. The frame is provided with an entrance-and-exit for a banknote. One end of the guide plate adjacent to the entrance-and-exit is pivotally connected to the frame, and the guide plate is operative to rotate around an axis of a pivoting shaft and is configured to guide a moving direction of the banknote when the banknote is being collected. The pressing plate is configured to support the collected banknotes and press the banknotes towards the guide plate while the banknotes are being separated.

Abstract: A semiconductor device includes a first carrier including a first pad, a second carrier including a second pad disposed opposite to the first pad, a joint coupled with and standing on the first pad, a joint encapsulating the post and bonding the first pad with the second pad, a first entire contact interface between the first pad and the joint, a second entire contact interface between the first pad and the post, and a third entire contact interface between the joint and the second pad. The first entire contact interface, the second entire contact interface and the third entire contact interface are flat surfaces. A distance between the first entire contact interface and the third entire contact interface is equal to a distance between the second entire contact interface and the third entire contact interface. The second entire contact interface is a continuous surface.

Abstract: A fingerprint recognition apparatus with fingerprint data compression is introduced, including: a pixel array obtaining a fingerprint data; a control circuit coupling to the pixel array and obtaining characteristic values of the pixel array; an effective fingerprint distribution judgement circuit coupling to the pixel array and determining a first part of the pixel array as an effective fingerprint zone and a second part of the pixel array as an invalid fingerprint zone according to the characteristic values of each row of the pixel array; and a multi-compressing circuit coupling to the effective fingerprint distribution judgement circuit and compressing the fingerprint data in the effective fingerprint zone with a first compression method and compressing the fingerprint data in the invalid fingerprint zone with a second compression method.

Abstract: Provided are a compensation structure and a driving method thereof, a display panel, and a display device. The compensation structure includes a photoelectric sensing circuit, a fingerprint recognition circuit and a compensation circuit. The photoelectric sensing circuit is configured to respectively generate a first electric signal and a second electric signal according to received first optical signal and second optical signal. The fingerprint recognition circuit is configured to be connected to the photoelectric sensing circuit to receive the first electric signal, and to employ the first electric signal to determine a fingerprint pattern. The compensation circuit is configured to be connected to the photoelectric sensing circuit to receive the second electric signal, and to employ the second electric signal to perform optical compensation so as to adjust the first electric signal.

Abstract: The present disclosure relates to a light emitting device, a method for preparing the same and a display device. The light emitting device includes a cathode layer, a quantum dot light emitting layer, a hole injection layer and an anode layer which are laminated. The hole injection layer includes a complex metal oxide film comprising two metal oxides that is at least partially oxidated.

Abstract: Package structures and methods for forming the same are provided. The package structure includes an integrated circuit die and a package layer surrounding the integrated circuit die. The package structure also includes a redistribution structure over the package layer and electrically connected to the integrated circuit die. The redistribution structure includes a passivation layer and a conductive layer formed in the passivation layer. The integrated circuit die further includes a connector formed over the conductive layer and covered a top surface of the passivation layer. In addition, a bottom surface of the connector and a top surface of the connector are both wider than a neck portion of the connector.

Abstract: The disclosure provides an experimental calibration method of a redundant inertial measurement unit including, step (1), establishing an installation angle model using a cone descriptive scheme, and obtaining a relationship of an angular speed of a carrier and an angular speed measured by each gyroscope, step (2), establishing a standard calibration model of the redundant inertial measurement unit based on a relationship between a sensor coordinate system and a carrier coordinate system, step (3), establishing a state equation and a measurement equation of a filter, step (4), performing a row amplification of measurement amounts based on the measurement equation established in step (3), and obtaining an amplificated measurement equation for improving observability, and step (5), obtaining a Jacobi matrix and a Hessian matrix based on the amplificated measurement equation, and estimating error parameters by an extended Kalman filtering algorithm based on a second-order Taylor expansion.

Abstract: Light control for improved near infrared sensitivity and channel separation for an image sensor. In one embodiment, an image sensor includes: a plurality of photodiodes arranged in rows and columns of a pixel array; and a light filter layer having a plurality of light filters configured over the plurality of photodiodes. The light filter layer has a first side facing the plurality of photodiodes and a second side facing away from the first side. The image sensor also includes a color filter layer having a plurality of color filters configured over the plurality of photodiodes. The color filter layer has a first surface facing the second side of the light filter layer and a second surface facing away from the first layer. Individual micro-lenses are configured to direct incoming light through corresponding light filter and color filter onto the respective photodiode.

Abstract: A method of packaging an integrated circuit includes forming a first integrated circuit and a second integrated circuit on a wafer, the first and second integrated circuit separated by a singulation region. The method includes covering the first and second integrated circuits with a molding compound, and sawing through the molding compound and a top portion of the wafer using a beveled saw blade, while leaving a bottom portion of the wafer remaining. The method further includes sawing through the bottom portion of the wafer using a second saw blade, the second saw blade having a thickness that is less than a thickness of the beveled saw blade. The resulting structure is within the scope of the present disclosure.

Abstract: A rechargeable battery device, specifically a scalable 3D lithium metal anode, and a method of manufacturing the same is disclosed. The scalable 3D electrode can serve as a lithium (Li) metal host that enables stable lithium metal cycling. Furthermore, the electrode can be fabricated by coating a slurry of well mixed LiNO3, carbon black, and PVDF on a Cu foil. For example, a 3D electrode can include a binder and a plurality of additives, wherein the plurality of additives comprise at least one conductive additive and at least one solid electrolyte interface (SEI) formation additive. The conductive additive can include electronic conductors, where the conductors are selected from a group consisting of carbon black, carbon nanotubes, carbon fibers, vapor grown carbon fiber (VGCF), graphite, and graphene. The SEI formation additives are selected from a group consisting of LiNO3, RbNO3, KNO3, CsNO3, LiFSI, LiAsF6, LiF, Li2O, Li2CO3, Li3PO4, SiO2, and Li3N.

Abstract: Techniques and architectures to provide multiple application servers each having at least one connection agent and at least one enabler agent and at least one database organized as multiple nodes. An error condition between a first connection agent and a first database node is detected. The first connection agent indicates that the first database node is unavailable to stop attempts to access the first database node by a first application server. A first enabler agent periodically checks availability of the first database node. The first database node is indicated as available in response to a pre-selected number of successful attempts to contact the first database node with the first enabler agent. The first database node is accessed with the application server in response to the indication that the first database node is available.

Abstract: The present invention discloses a type-B crystal form of fenolamine, a preparation method thereof, and a composition and use thereof, more particularly a type-B crystal form of the fenolamine compound (chemical name: trans-2-(2,5-dimethoxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)-N-(4-hydroxyphenylethyl)acrylamide, a preparation method thereof, and a composition and use thereof. Specifically, the present invention discloses the presence of a solid of a type-B fenolamine crystal form in solid state; a method for preparing the solid of type-B crystal form; and use of the solid of the type-B fenolamine crystal form as a pharmaceutical active ingredient in the manufacture of a medicament for prevention and treatment of Parkinson's disease (PD), improvement of learning and memory disorder, and treatment of memory loss and Alzheimer's disease (AD).

Abstract: Protein nog1 is used in the regulation of plant yield and/or grain number. The transgenic treated Guichao 2 in which the expression of the protein nog1 is inhibited has a reduced yield per plant and/or a reduced grain number of the main stem as compared with untreated Guichao 2. The transgenic plant obtained by introducing a nucleic acid molecule encoding the protein nog1 into SIL176 has an increased yield per plant and/or an increased grain number of the main stem as compared with untransformed SIL176.

Abstract: A three-dimension measurement device includes a moving device, a projecting device, a surface-type image-capturing device and a processing device. The moving device carries an object, and moves the object to a plurality of positions. The projecting device generates a first light to the object. The surface-type image-capturing device senses a second light generated by the object in response to the first light to generate a phase image on each of the positions. The processing device is coupled to the surface-type image-capturing device and receives the phase images. The processing device performs a region-of-interest (ROI) operation for the phase images to generate a plurality of ROI images. The processing device performs a multi-step phase-shifting operation for the ROI images to calculate the surface height distribution of the object.

Abstract: A bifacial light-harvesting dye-sensitized solar cell is provided and has: a first transparent substrate, a second transparent substrate, a working electrode, a first semiconductor layer, a second semiconductor layer, a third semiconductor layer, a counter electrode, a light-transmitting catalyst layer, and a liquid electrolyte. A photoelectric conversion efficiency of the dye-sensitized solar cell is improved by using a specific working electrode structure.

Abstract: Light control for improved near infrared sensitivity and channel separation for an image sensor. In one embodiment, an image sensor includes: a plurality of photodiodes arranged in rows and columns of a pixel array; and a light filter layer having a plurality of light filters configured over the plurality of photodiodes. The light filter layer has a first side facing the plurality of photodiodes and a second side facing away from the first side. The image sensor also includes a color filter layer having a plurality of color filters configured over the plurality of photodiodes. The color filter layer has a first surface facing the second side of the light filter layer and a second surface facing away from the first layer. Individual micro-lenses are configured to direct incoming light through corresponding light filter and color filter onto the respective photodiode.

Abstract: The present disclosure provides an optical touch device and a manufacturing method thereof, a display and an electronic device, wherein the optical touch device comprises: a pixel array (11) that comprises a plurality of pixel sub-circuits (101) each of which comprises M first pixels (1011) and N second pixels (1012), wherein detection rays with a preset frequency are emitted by the second pixels (1012), where M and N are positive integers; a light receiving array (12) that comprises a plurality of light receivers (121) corresponding, at a one-to-one basis, to the plurality of pixel sub-circuits (101), wherein each of the light receivers (121) generates an sensing signal by receiving reflected rays of the detection rays emitted by a corresponding second pixel (1012); and a detection circuit (13) connected with the plurality of light receivers (121), wherein the detection circuit (13) performs touch positioning.

Abstract: A fiber-optic communication system includes a first optical transceiver and a second optical transceiver. First, the first optical transceiver is configured to transmit signals to the second optical transceiver using an optical transmission power having an initial value. When the optical receiving power inputted into the second optical transceiver is larger than the expected input power of the second optical transceiver, a power compensation value is acquired according to the optical receiving power and the expected input power. The first optical transceiver is configured adjust its optical transmission power according to the power compensation value and then transmit signals to the second optical transceiver using the adjusted optical transmission power.

Abstract: The present invention is directed to azabicyclo[4.1.0]heptane compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.