Abstract: Systems and methods of downloading and rendering data from a server or other source on a user's computer system wherein the data is a set of nested data categories are disclosed. The set of nested data categories further comprise a set of active logic levels where the set of active logic levels may be dynamically changed, depending on the size of the browser that the user of the computer system may set. In one embodiment, the user's computer system has a desktop or laptop sized screen upon which to render data. If the user resizes the browser to be substantially the size of a mobile screen, then the present system may dynamically adjust the logic levels (e.g., changing the number of click targets within the browser) to better facilitate a scrolling experience within the browser.

Abstract: Provision of fabrication, construction, and/or assembly of a memory device including a two-terminal memory portion is described herein. The two-terminal memory device fabrication can provide enhanced capabilities in connection with precisely tuning on-state current over a greater possible range.

Abstract: An optical imaging system includes a thin film imager that is able to create images of objects in various modes of imaging such as bright field, dark field, frustrated total internal reflection, fly eye, and the like. The imaging system may be an integrated optical design that performs different modes of optical imaging in the same imaging device by positioned pin hole structures in geometries that capture images according to the desired mode of imaging.

Abstract: A low stress sacrificial cap layer 120 having a silicon oxide liner film 130, a low stress silicon film 140, and a silicon nitride film Alternatively, a low stress sacrificial cap layer 410 having a silicon oxide liner film 130 and a graded silicon nitride film 420. Also, methods 300, 500 for fabricating a transistor 20, 400 having a low stress sacrificial cap layer 120, 410.

Abstract: A power converting circuit includes an upper gate switch, a transistor, a current source circuit, a comparator circuit, a delay circuit, and a pulse width modulation signal generating circuit. The transistor and the current source circuit provide a reference signal. The comparator circuit generates a comparing signal according to the reference signal and an output signal provided by the upper gate switch. The delay circuit generates a delay signal according to the comparing signal and a clock signal. The pulse width modulation signal generating circuit generates a control signal for the upper gate switch according to the delay signal and the clock signal for configuring the conduction status of the upper gate switch. The power converting circuit adjusts the conduction time of the upper gate switch according to the reference signal and the output signal.

Abstract: The invention features compositions and methods for inhibiting the Pin1 protein, and the treatment of disorders characterized by elevated Pin1 levels.

Abstract: This invention provides compounds of Formula I: (Formula I should be inserted here) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising a compound of Formula I; and use of a compound of Formula I for treating specified cancers.

Abstract: This invention provides compounds of Formula (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising a compound of Formula (I); and use of a compound of Formula (I) for treating specified cancers.

Abstract: A sensing device includes a comparator, a first and a second variable capacitor unit. A first comparator input of the comparator is electrically coupled to a touch pad. The first variable capacitor unit is configured to charge the first comparator input such that the first comparator input has a first potential. The second variable capacitor unit is configured to charge a second comparator input of the comparator such that the second comparator input has a second potential. The comparator is configured for comparing the first potential and the second potential to generate a comparator output signal. In a condition of the touch pad being operated, the first variable capacitor unit is adjusted according to the comparator output signal to perform potential compensation for the first comparator input, or the second variable capacitor unit is adjusted according to the comparator output signal to perform potential compensation for the second comparator input.

Abstract: Provided are compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X and m are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof. Also provided are methods of using a compound of Formula I, or a pharmaceutically acceptable salt thereof.

Abstract: Provided are compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X and m are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof. Also provided are methods of using a compound of Formula I, or a pharmaceutically acceptable salt thereof.

Abstract: The invention features methods of treating a proliferative disorder characterized by elevated Pin1 marker levels and/or reduced Pin1 Ser71 phosphorylation in a subject by administering a retinoic acid compound. Additionally, the invention features methods of treating proliferative disorders (e.g., proliferative disorders characterized by elevated Pin1 marker levels) by administering a retinoic acid compound in combination with another anti-proliferative compound. Finally, the invention also features methods including high-throughput screens for discovering and validating Pin1 inhibitors.

Abstract: The present invention features methods and compositions for the generation and use of conformation-specific antibodies or fragments thereof.

Abstract: Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.

Abstract: The present invention discloses a charge control circuit for supplying power from an external power source to a first common node and charging a second common node from the first common node. A regulator circuit is coupled between the external power source and the first common node, and a transistor is coupled between the first common node and the second common node. The present invention detects an operation parameter of the transistor and controls an internal voltage source to generate a non-predetermined voltage difference accordingly. When the sum of the voltage at the second common node and the non-predetermined voltage is equal to or higher than the reference voltage, the voltage at the first common node is regulated to a level higher than the voltage at the second common node, and the transistor is in an optimum conductive state.

Abstract: A computer-implemented method for automatically pausing advertisements based on user attention includes rendering a digital video to a user, in response to the user initiating the digital video through a web multimedia player. The computer-implemented method also includes streaming an advertisement to the user once the user begins to watch the digital video and monitoring the user attention as the user watches the advertisement. The user attention is monitored based on keystrokes and mouse movements. Further, the computer-implemented method includes detecting one or more changes in the user attention. Furthermore, the computer-implemented method includes pausing the advertisement automatically at instance of detecting the one or more changes. Moreover, the computer-implemented method includes detecting the one or more changes that directs the user attention to the paused advertisement and resuming streaming of the advertisement.

Abstract: A light-emitting element includes a reflective layer; a first transparent layer on the reflective layer; a light-emitting stack having an active layer on the first transparent layer; and a cavity formed in the first transparent layer.

Abstract: Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.

Abstract: This document provides methods and materials related to transcription terminators. For example, methods and materials related to transcription terminators and nucleic acid molecules (e.g., vectors and constructs) that contain a nucleic acid sequence that encodes a polypeptide operably linked to a transcription terminator are provided. In addition, plants, plant cells, and plant seeds having a nucleic acid sequence that encodes a polypeptide operably linked to a transcription terminator are provided.

Abstract: Provided are compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R7, X, Z1, Z2, Z3, Z4 and m are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof. Also provided are methods of using a compound of Formula I, or a pharmaceutically acceptable salt thereof.