Abstract: The present invention relates to methods for the recombinant expression of chlamydia major outer membrane protein (MOMP) comprising transforming a population of E. coli host cells with an expression vector comprising a nucleic acid molecule that encodes chlamydia MOMP and encodes a leader sequence for targeting the MOMP to the outer membrane of the cell, wherein the nucleic acid molecule is operatively linked to a promoter. The method of the invention allows expression of MOMP in the outer membrane of the cell, which leads to protein folding that is more like native MOMP relative to a MOMP protein that is expressed intracellularly. Also provided by the invention are uses of the recombinant MOMP in pharmaceutical compositions and methods for the treatment and/or prophylaxis of chlamydia infection and/or the effects thereof.

Abstract: The present invention relates to methods for the recombinant expression of chlamydia major outer membrane protein (MOMP) comprising transforming a population of E. coli host cells with an expression vector comprising a nucleic acid molecule that encodes chlamydia MOMP and encodes a leader sequence for targeting the MOMP to the outer membrane of the cell, wherein the nucleic acid molecule is operatively linked to a promoter. The method of the invention allows expression of MOMP in the outer membrane of the cell, which leads to protein folding that is more like native MOMP relative to a MOMP protein that is expressed intracellularly. Also provided by the invention are uses of the recombinant MOMP in pharmaceutical compositions and methods for the treatment and/or prophylaxis of chlamydia infection and/or the effects thereof.

Abstract: The present invention relates to methods for the recombinant expression of chlamydia major outer membrane protein (MOMP) comprising transforming a population of E. coli host cells with an expression vector comprising a nucleic acid molecule that encodes chlamydia MOMP and encodes a leader sequence for targeting the MOMP to the outer membrane of the cell, wherein the nucleic acid molecule is operatively linked to a promoter. The method of the invention allows expression of MOMP in the outer membrane of the cell, which leads to protein folding that is more like native MOMP relative to a MOMP protein that is expressed intracellularly. Also provided by the invention are uses of the recombinant MOMP in pharmaceutical compositions and methods for the treatment and/or prophylaxis of chlamydia infection and/or the effects thereof.

Abstract: A jig saw including a clamping mechanism for removably clamping a saw blade and a driving mechanism. The clamping mechanism includes an actuating member and a clamping mechanism, the actuating member is configured to rotate about a first axis, thereby driving the clamping mechanism to achieve locking or unlocking of the saw blade. The actuating member includes an inclined surface extending in a rotation direction of the actuating member. The inclined surface cooperates with the clamping mechanism thereby to drive the clamping mechanism when the actuating member rotates. Since the clamping mechanism of the jig saw uses a clamping mechanism to apply pressure to the saw blade from the side, thereby abutting and fixing it on the main body, such a clamping mechanism therefore can be applied to different types of saw blades, regardless of the shape of the end faces of their clamping ends (e.g., V-shaped or U-shaped).

Abstract: The present invention relates to methods for the recombinant expression of chlamydia major outer membrane protein (MOMP) comprising transforming a population of E. coli host cells with an expression vector comprising a nucleic acid molecule that encodes chlamydia MOMP and encodes a leader sequence for targeting the MOMP to the outer membrane of the cell, wherein the nucleic acid molecule is operatively linked to a promoter. The method of the invention allows expression of MOMP in the outer membrane of the cell, which leads to protein folding that is more like native MOMP relative to a MOMP protein that is expressed intracellularly. Also provided by the invention are uses of the recombinant MOMP in pharmaceutical compositions and methods for the treatment and/or prophylaxis of chlamydia infection and/or the effects thereof.

Abstract: A pharmaceutical composition comprising bisacodyl [4,4?-(pyridine-2-ylmethylene)bis(4,1-phenylene) diacetate], a solvent, a buffer, and a polymer, methods and apparatus for delivery to a patient.

Abstract: A ball pickup device is provided, comprising a ball collector and a pull rod connected to the ball connector. The ball collector has ball inlets formed at the bottom of the ball collector and formed by transverse rods arranged at the bottom of the ball collector in parallel at intervals, and one ball outlet is formed by the interval between every two adjacent transverse rods. Each interval is smaller than the diameter of a ball. One end of each transverse rod is fixedly connected to the ball collector, and the other end is a movable end and located in the corresponding receding groove. When a ball is pressed, movable ends move along receding grooves to recede under the pressure of the ball, and the ball enters the ball collector. After the ball enters the ball inlet, movable ends move along receding grooves to gradually return.

Abstract: A ball pickup device is provided, comprising a ball collector and a pull rod connected to the ball connector. The ball collector has ball inlets formed at the bottom of the ball collector and formed by transverse rods arranged at the bottom of the ball collector in parallel at intervals, and one ball outlet is formed by the interval between every two adjacent transverse rods. Each interval is smaller than the diameter of a ball. One end of each transverse rod is fixedly connected to the ball collector, and the other end is a movable end and located in the corresponding receding groove. When a ball is pressed, movable ends move along receding gooves to recede under the pressure of the ball, and the ball enters the ball collector. After the ball enters the ball inlet, movable ends move along receding grooves to gradually return.

Abstract: A pharmaceutical composition comprising bisacodyl [4,4?-(pyridine-2-ylmethylene)bis(4,1-phenylene) diacetate], a solvent, a buffer, and a polymer, methods and apparatus for delivery to a patient.

Abstract: A pharmaceutical composition for the treatment of hemorrhoids, sheets, methods of making and using the same.

Abstract: A composition for treating and preventing diaper rash comprises zinc oxide, dimethicone, mineral oil, a suspending agent, and an emulsifier. The emulsifier has a Hydrophile-Lipophile Balance number of at most 4.5 and the composition is sprayable. The suspending agent may be a hydrophobic clay.

Abstract: A signal receiving structure and an electronic device having the same are disclosed. The signal receiving structure used for the electronic device to receive an infrared signal includes a signal receiving area, a first block, a second block, and a third block. The signal receiving area is used to receive the infrared signal. The first block is connected to the signal receiving area and the infrared signal is transmitted therethrough. The second block is connected to the first block. A specific angle is interposed between the first block and the second block, such that the infrared signal can be transmitted through the second block by total reflection. The third block is connected to the second block and has a signal output area for the infrared signal to emit by the signal output area after total reflection. The signal receiving area is smaller than the signal output area.

Abstract: The present invention provides genetic markers on human chromosome 19 that are associated with a beneficial response to interferon alpha (IFN-?). These IFN-? response markers are useful, inter alia, to identify patients who are most likely to benefit from treatment with IFN-? pharmaceutical compositions and drug products, in methods of treating patients having a disease susceptible to treatment with an IFN-?, and in methods for selecting the most appropriate therapy for such patients.

Abstract: The present invention provides genetic markers on human chromosome 19 that are associated with a beneficial response to interferon alpha (IFN-?). These IFN-? response markers are useful, inter alia, to identify patients who are most likely to benefit from treatment with IFN-? pharmaceutical compositions and drug products, in methods of treating patients having a disease susceptible to treatment with an IFN-?, and in methods for selecting the most appropriate therapy for such patients.

Abstract: The present invention provides genetic markers and biomarkers that are associated with anemia induced by ribavirin therapy. The genetic markers are located in the ITPA gene and elsewhere on human chromosome 20 and the biomarkers are low ITPA activity phenotypes. These markers of ribavirin-induced anemia are useful, inter alia, to identify patients who are least likely to develop anemia upon treatment with ribavirin pharmaceutical compositions and drug products, in methods of treating patients having a disease susceptible to treatment with ribavirin, and in methods for selecting the most appropriate therapy for such patients.

Abstract: A testing stylus used for testing a keyboard, includes a sleeve, a resisting member and an elastic member, the resisting member be conductive and have an engageable end and an opposite resisting end, the resisting end is used to resist against the keyboard. The resisting member and the elastic member are assembled in the sleeve, the elastic member resists against the engageable end, to allow the resisting end to be exposed to the outside from the sleeve, the resisting end is withdrawn into the sleeve by pressing the sleeve.

Abstract: An inductor circuit with high quality (Q) factor includes a primary inductor and a compensation sub-circuit. The compensation sub-circuit is electrically isolated from the primary inductor. The compensation sub-circuit is magnetically coupled with the primary inductor to compensate the loss in the primary inductor.

Abstract: A fixing mechanism for fixing a display device is disclosed. The fixing mechanism includes a housing whereon a first hole and a protrusion are formed, and a bracket installed on a side of the housing. The bracket includes a connecting part for connecting the housing. A second hole and an opening are formed on the connecting part, and the protrusion passes through the opening. The bracket further includes a bending part connected to the connecting part for shielding the second hole. The fixing mechanism further includes a fastening component passing through the first hole on the housing and the second hole on the connecting part for fastening the bracket on the housing.

Abstract: A testing stylus used for testing a keyboard, includes a sleeve, a resisting member and an elastic member, the resisting member be conductive and have an engageable end and an opposite resisting end, the resisting end is used to resist against the keyboard. The resisting member and the elastic member are assembled in the sleeve, the elastic member resists against the engageable end, to allow the resisting end to be exposed to the outside from the sleeve, the resisting end is withdrawn into the sleeve by pressing the sleeve.

Abstract: A processing method for group resource allocation comprises that: a base station establishes groups according to modulation and coding schemes and/or resource sizes (202), the modulation and coding schemes and/or resource sizes supported by the groups are static or quasi-static (204). With the present invention, the groups can be established based on modulation and coding schemes and/or resource sizes, and the modulation and coding schemes and/or resource sizes of the groups can be changed, compared with the prior art, the complexity of the group resource allocation method in the wireless communication system and the control overhead can be reduced, and the transmission bandwidth utilization of the wireless communication system can be improved.