Patents by Inventor Ping Qiu

Ping Qiu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240297835
    Abstract: A monitoring system includes a non-transitory computer readable medium configured to store instructions; and a processor. The processor is configured to execute the instructions for retrieving performance data from a performance network register (PNR) for each of a plurality of servers, wherein the servers are configured to implement a functionality of the system, and retrieving the performance data includes avoiding directly accessing the servers. The processor is configured to execute the instructions for storing the received performance data for each server in association with identification information for a corresponding server. The processor is configured to execute the instructions for receiving parameters for generating a display of monitored data. The processor is further configured to execute the instructions for accessing the stored performance data to generate the display of monitored data; and transmitting the display of monitored data to at least one operator system.
    Type: Application
    Filed: June 30, 2022
    Publication date: September 5, 2024
    Inventors: Xiqian ZHENG, Ping QIU, Goa SUKEGAWA
  • Publication number: 20220378892
    Abstract: The present invention relates to methods for the recombinant expression of chlamydia major outer membrane protein (MOMP) comprising transforming a population of E. coli host cells with an expression vector comprising a nucleic acid molecule that encodes chlamydia MOMP and encodes a leader sequence for targeting the MOMP to the outer membrane of the cell, wherein the nucleic acid molecule is operatively linked to a promoter. The method of the invention allows expression of MOMP in the outer membrane of the cell, which leads to protein folding that is more like native MOMP relative to a MOMP protein that is expressed intracellularly. Also provided by the invention are uses of the recombinant MOMP in pharmaceutical compositions and methods for the treatment and/or prophylaxis of chlamydia infection and/or the effects thereof.
    Type: Application
    Filed: July 1, 2022
    Publication date: December 1, 2022
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Lan Zhang, Zhiyun Wen, Craig T. Przysiecki, Puneet Khandelwal, Ping Qiu
  • Patent number: 11406695
    Abstract: The present invention relates to methods for the recombinant expression of chlamydia major outer membrane protein (MOMP) comprising transforming a population of E. coli host cells with an expression vector comprising a nucleic acid molecule that encodes chlamydia MOMP and encodes a leader sequence for targeting the MOMP to the outer membrane of the cell, wherein the nucleic acid molecule is operatively linked to a promoter. The method of the invention allows expression of MOMP in the outer membrane of the cell, which leads to protein folding that is more like native MOMP relative to a MOMP protein that is expressed intracellularly. Also provided by the invention are uses of the recombinant MOMP in pharmaceutical compositions and methods for the treatment and/or prophylaxis of chlamydia infection and/or the effects thereof.
    Type: Grant
    Filed: June 8, 2020
    Date of Patent: August 9, 2022
    Assignee: Merck Sharp & Dohme LLC
    Inventors: Lan Zhang, Zhiyun Wen, Craig T. Przysiecki, Ping Qiu
  • Publication number: 20210093703
    Abstract: The present invention relates to methods for the recombinant expression of chlamydia major outer membrane protein (MOMP) comprising transforming a population of E. coli host cells with an expression vector comprising a nucleic acid molecule that encodes chlamydia MOMP and encodes a leader sequence for targeting the MOMP to the outer membrane of the cell, wherein the nucleic acid molecule is operatively linked to a promoter. The method of the invention allows expression of MOMP in the outer membrane of the cell, which leads to protein folding that is more like native MOMP relative to a MOMP protein that is expressed intracellularly. Also provided by the invention are uses of the recombinant MOMP in pharmaceutical compositions and methods for the treatment and/or prophylaxis of chlamydia infection and/or the effects thereof.
    Type: Application
    Filed: June 8, 2020
    Publication date: April 1, 2021
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Lan Zhang, Zhiyun Wen, Craig T. Przysiecki, Puneet Khandelwal, Ping Qiu
  • Publication number: 20190046626
    Abstract: The present invention relates to methods for the recombinant expression of chlamydia major outer membrane protein (MOMP) comprising transforming a population of E. coli host cells with an expression vector comprising a nucleic acid molecule that encodes chlamydia MOMP and encodes a leader sequence for targeting the MOMP to the outer membrane of the cell, wherein the nucleic acid molecule is operatively linked to a promoter. The method of the invention allows expression of MOMP in the outer membrane of the cell, which leads to protein folding that is more like native MOMP relative to a MOMP protein that is expressed intracellularly. Also provided by the invention are uses of the recombinant MOMP in pharmaceutical compositions and methods for the treatment and/or prophylaxis of chlamydia infection and/or the effects thereof.
    Type: Application
    Filed: November 16, 2015
    Publication date: February 14, 2019
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Lan Zhang, Zhiyun Wen, Craig T. Przysiecki, Puneet Khandelwal, Ping Qiu
  • Patent number: 9993426
    Abstract: A pharmaceutical composition comprising bisacodyl [4,4?-(pyridine-2-ylmethylene)bis(4,1-phenylene) diacetate], a solvent, a buffer, and a polymer, methods and apparatus for delivery to a patient.
    Type: Grant
    Filed: September 7, 2016
    Date of Patent: June 12, 2018
    Assignee: C. B. Fleet Company, Inc.
    Inventors: Nelson P. Ayala, Ping Qiu, Debanjan Das, Dave Zimmerman
  • Patent number: 9839816
    Abstract: A ball pickup device is provided, comprising a ball collector and a pull rod connected to the ball connector. The ball collector has ball inlets formed at the bottom of the ball collector and formed by transverse rods arranged at the bottom of the ball collector in parallel at intervals, and one ball outlet is formed by the interval between every two adjacent transverse rods. Each interval is smaller than the diameter of a ball. One end of each transverse rod is fixedly connected to the ball collector, and the other end is a movable end and located in the corresponding receding groove. When a ball is pressed, movable ends move along receding grooves to recede under the pressure of the ball, and the ball enters the ball collector. After the ball enters the ball inlet, movable ends move along receding grooves to gradually return.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: December 12, 2017
    Inventor: Ping Qiu
  • Publication number: 20170266515
    Abstract: A ball pickup device is provided, comprising a ball collector and a pull rod connected to the ball connector. The ball collector has ball inlets formed at the bottom of the ball collector and formed by transverse rods arranged at the bottom of the ball collector in parallel at intervals, and one ball outlet is formed by the interval between every two adjacent transverse rods. Each interval is smaller than the diameter of a ball. One end of each transverse rod is fixedly connected to the ball collector, and the other end is a movable end and located in the corresponding receding groove. When a ball is pressed, movable ends move along receding gooves to recede under the pressure of the ball, and the ball enters the ball collector. After the ball enters the ball inlet, movable ends move along receding grooves to gradually return.
    Type: Application
    Filed: May 22, 2015
    Publication date: September 21, 2017
    Inventor: Ping QIU
  • Publication number: 20170079911
    Abstract: A pharmaceutical composition comprising bisacodyl [4,4?-(pyridine-2-ylmethylene)bis(4,1-phenylene) diacetate], a solvent, a buffer, and a polymer, methods and apparatus for delivery to a patient.
    Type: Application
    Filed: September 7, 2016
    Publication date: March 23, 2017
    Inventors: Nelson P. Ayala, Ping Qiu, Debanjan Das, Dave Zimmerman
  • Publication number: 20170056332
    Abstract: A pharmaceutical composition for the treatment of hemorrhoids, sheets, methods of making and using the same.
    Type: Application
    Filed: August 29, 2016
    Publication date: March 2, 2017
    Inventors: Nelson P. Ayala, Ping Qiu, Debanjan Das
  • Patent number: 9526783
    Abstract: A composition for treating and preventing diaper rash comprises zinc oxide, dimethicone, mineral oil, a suspending agent, and an emulsifier. The emulsifier has a Hydrophile-Lipophile Balance number of at most 4.5 and the composition is sprayable. The suspending agent may be a hydrophobic clay.
    Type: Grant
    Filed: December 5, 2014
    Date of Patent: December 27, 2016
    Assignee: C.B. Fleet Company Incorporated
    Inventors: Debanjan Das, Ping Qiu, Nelson P. Ayala
  • Publication number: 20130251677
    Abstract: The present invention provides genetic markers on human chromosome 19 that are associated with a beneficial response to interferon alpha (IFN-?). These IFN-? response markers are useful, inter alia, to identify patients who are most likely to benefit from treatment with IFN-? pharmaceutical compositions and drug products, in methods of treating patients having a disease susceptible to treatment with an IFN-?, and in methods for selecting the most appropriate therapy for such patients.
    Type: Application
    Filed: May 30, 2013
    Publication date: September 26, 2013
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Arthur Bertelsen, Jacques Fellay, Dongliang Ge, David B. Goldstein, John G. McHutchison, Ping Qiu, Kevin Shianna, Jason S. Simon, Alexander J. Thompson, Thomas Urban
  • Patent number: 8535887
    Abstract: The present invention provides genetic markers on human chromosome 19 that are associated with a beneficial response to interferon alpha (IFN-?). These IFN-? response markers are useful, inter alia, to identify patients who are most likely to benefit from treatment with IFN-? pharmaceutical compositions and drug products, in methods of treating patients having a disease susceptible to treatment with an IFN-?, and in methods for selecting the most appropriate therapy for such patients.
    Type: Grant
    Filed: May 21, 2010
    Date of Patent: September 17, 2013
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Arthur Bertelsen, Jacques Fellay, Dongliang Ge, David B. Goldstein, John G. McHutchison, Ping Qiu, Kevin Shianna, Jason S. Simon, Alexander J. Thompson, Thomas Urban
  • Publication number: 20120282224
    Abstract: The present invention provides genetic markers and biomarkers that are associated with anemia induced by ribavirin therapy. The genetic markers are located in the ITPA gene and elsewhere on human chromosome 20 and the biomarkers are low ITPA activity phenotypes. These markers of ribavirin-induced anemia are useful, inter alia, to identify patients who are least likely to develop anemia upon treatment with ribavirin pharmaceutical compositions and drug products, in methods of treating patients having a disease susceptible to treatment with ribavirin, and in methods for selecting the most appropriate therapy for such patients.
    Type: Application
    Filed: November 5, 2010
    Publication date: November 8, 2012
    Inventors: Janice K. Albrecht, Clifford A. Brass, Jacques Fellay, Dongliang Ge, David B. Goldstein, Curtis Gumbs, John G. McHutchinson, Ping Qiu, Kevin Shianna, Alexander J. Thompson, Thomas J. Urban
  • Patent number: 8237531
    Abstract: An inductor circuit with high quality (Q) factor includes a primary inductor and a compensation sub-circuit. The compensation sub-circuit is electrically isolated from the primary inductor. The compensation sub-circuit is magnetically coupled with the primary inductor to compensate the loss in the primary inductor.
    Type: Grant
    Filed: December 31, 2007
    Date of Patent: August 7, 2012
    Assignee: GLOBALFOUNDRIES Singapore Pte. Ltd.
    Inventors: Ping Qiu, Chirn Chye Boon, Johnny Kok Wai Chew, Kiat Seng Yeo, Manh Anh Do, Lap Chan, Suh Fei Lim
  • Publication number: 20120044892
    Abstract: A processing method for group resource allocation comprises that: a base station establishes groups according to modulation and coding schemes and/or resource sizes (202), the modulation and coding schemes and/or resource sizes supported by the groups are static or quasi-static (204). With the present invention, the groups can be established based on modulation and coding schemes and/or resource sizes, and the modulation and coding schemes and/or resource sizes of the groups can be changed, compared with the prior art, the complexity of the group resource allocation method in the wireless communication system and the control overhead can be reduced, and the transmission bandwidth utilization of the wireless communication system can be improved.
    Type: Application
    Filed: December 24, 2009
    Publication date: February 23, 2012
    Applicant: ZTE CORPORATION
    Inventors: Yanfeng Guan, Wei Xia, Ying Liu, Ping Qiu, Huiying Fang
  • Publication number: 20100297080
    Abstract: The present invention provides genetic markers on human chromosome 19 that are associated with a beneficial response to interferon alpha (IFN-?). These IFN-? response markers arc useful, inter alia, to identify patients who are most likely to benefit from treatment with IFN-? pharmaceutical compositions and drug products, in methods of treating patients having a disease susceptible to treatment with an IFN-?, and in methods for selecting the most appropriate therapy for such patients.
    Type: Application
    Filed: May 21, 2010
    Publication date: November 25, 2010
    Inventors: ARTHUR BERTELSEN, JACQUES FELLAY, DONGLANG GE, DAVID GOLDSTEIN, JOHN G. MCHUTCHISON, NICHOLAS J. MURGOLO, PING QIU, ROBERT ORVILLE RALSTON, II, KEVIN SHIANNA, JASON S. SIMON, ALEXANDER J. THOMPSON, THOMAS URBAN
  • Publication number: 20090167466
    Abstract: An inductor circuit with high quality (Q) factor includes a primary inductor and a compensation sub-circuit. The compensation sub-circuit is electrically isolated from the primary inductor. The compensation sub-circuit is magnetically coupled with the primary inductor to compensate the loss in the primary inductor.
    Type: Application
    Filed: December 31, 2007
    Publication date: July 2, 2009
    Applicants: CHARTERED SEMICONDUCTOR MANUFACTURING, LTD., NANYANG TECHNOLOGICAL UNIVERSITY
    Inventors: Ping QIU, Chirn Chye BOON, Johnny Kok Wai CHEW, Kiat Seng YEO, Manh Anh DO, Lap CHAN, Suh Fei LIM
  • Patent number: 7405575
    Abstract: A method and apparatus adapted to calibrate a signal path of a signal analysis system such that digital samples of a signal under test acquired by the system are processed for representing the impedance of a device under test. The method and apparatus calibrates the signal path to characterize transfer parameters of the device under test within a spectral domain. A reference impedance (Zref) is retrieved that is associated with the signal analysis system. The transfer parameters of the device under test and the reference impedance (Zref) are processed to effect thereby a representation of the device under test impedance (Zeq) as a function of frequency.
    Type: Grant
    Filed: August 23, 2006
    Date of Patent: July 29, 2008
    Assignee: Tektronix, Inc.
    Inventors: Kan Tan, John J. Pickerd, Ping Qiu
  • Publication number: 20080154567
    Abstract: The present invention relates to a method for developing algorithms that are capable of discriminating among different genotypes and subtypes of a virus of interest. The method includes aligning a set of viral nucleotide sequences having known genotypes and analyzing the aligned sequences to identify nucleotide positions at which the nucleotide is conserved within genotypes, but diversified across the different known genotypes. These positions, referred to herein as genotyping positions, are employed as predictive variables to compile a variable input table for analysis by a statistical classification algorithm. The variable input table also includes the nucleotide present at each genotyping position as a value and the genotype for each of the aligned sequences as a response variable.
    Type: Application
    Filed: December 19, 2007
    Publication date: June 26, 2008
    Inventors: Ping Qiu, Jonathan Richard Greene, Wei Ding, Qing Zhang