Patents by Inventor Ping-Shu Chen

Ping-Shu Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for making Biolimus A9
    Patent number: 7872122
    Abstract: A process for making Biolimus A9 comprises reacting sirolimus (or rapamycin) with alkyl benzene sulfonate under the catalyzing of organic base and in the presence of organic solvent to undergo a nucleophilic substitution reaction to obtain the Biolimus A9 with high yield, not only for small-scale laboratory experiment, but also for rendering reproducibility of high yield even after process amplification.
    Type: Grant
    Filed: May 8, 2009
    Date of Patent: January 18, 2011
    Assignee: Chunghwa Chemical Synthesis & Biotech Co., Ltd.
    Inventors: Kwang-Chung Lee, Ping-Shu Chen, Shu-Chuan Lin, Tzu-Ai Lee
  • Process for making Biolimus A9
    Publication number: 20090292118
    Abstract: A process for making Biolimus A9 comprises reacting sirolimus (or rapamycin) with alkyl benzene sulfonate under the catalyzing of organic base and in the presence of organic solvent to undergo a nucleophilic substitution reaction to obtain the Biolimus A9 with high yield, not only for small-scale laboratory experiment, but also for rendering reproducibility of high yield even after process amplification.
    Type: Application
    Filed: May 8, 2009
    Publication date: November 26, 2009
    Inventors: Kwang-Chung Lee, Ping-Shu Chen, Shu-Chuan Lin, Tzu-Ai Lee