Abstract: The present invention provides polypeptide modulators of complement activity, including cyclic polypeptide modulators. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: The present invention provides polypeptide modulators of complement activity, including cyclic polypeptide modulators. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: The present disclosure discloses an ankle prosthesis containing zirconium-niobium alloy on oxidation layer and a preparation method thereof, the preparation method comprises: using zirconium-niobium alloy powder as a raw material, conducting a 3D printing for one-piece molding to obtain an intermediate products of the talus part and tibial part, and performing Sinter-HIP, cryogenic cooling and surface oxidation to obtain talus part and tibial part. The talus part is connected with the tibial part in a sliding mode; a bone trabeculae is respectively arranged on the lower surface of the talus body and the outer surfaces of the two first fixations, and on the upper surface of the tibial body and the outer surfaces of the two second fixations as well, so as to improve bone ingrowth.

Abstract: The present invention provides modulators of complement activity. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: The present invention provides polypeptide modulators of complement activity, including cyclic polypeptide modulators. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: In some examples, a system includes a transceiver configured to receive surveillance messages from Y target vehicles, where Y is an integer greater than two. The system includes processing circuitry configured to determine predicted positions of the Y target vehicles based on the surveillance messages. The processing circuitry is also configured to determine reported positions of the Y target vehicles based on later received surveillance messages. The processing circuitry is further configured to determine that respective differences between the respective predicted position and the respective reported position for X of the Y target vehicles is greater than a threshold distance. The processing circuitry is configured to determine that Global Navigation Satellite System interference has occurred in response to determining that X divided by Y is greater than a threshold level.

Abstract: In some examples, a system includes a transceiver configured to receive surveillance messages from Y target vehicles, where Y is an integer greater than two. The system includes processing circuitry configured to determine predicted positions of the Y target vehicles based on the surveillance messages. The processing circuitry is also configured to determine reported positions of the Y target vehicles based on later received surveillance messages. The processing circuitry is further configured to determine that respective differences between the respective predicted position and the respective reported position for X of the Y target vehicles is greater than a threshold distance. The processing circuitry is configured to determine that Global Navigation Satellite System interference has occurred in response to determining that X divided by Y is greater than a threshold level.

Abstract: The present invention provides modulators of complement activity. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: Techniques for detecting and excluding spoofed Global Navigation Satellite System (GNSS) signals are described. Using position data acquired from inertial sensors, a line of sight (LOS) estimation can be determined to various satellites. This data can be compared with range data provided by a GNSS receiver, for example, by subtracting the LOS estimations with corresponding GNSS ranges. The difference can then be compared to an appropriate threshold to determine whether GNSS spoofing is present. Additionally, the non-spoofed GNSS signals can be used to generate an updated position solution, which is verified by an integrity algorithm. If verified, the updated position solution can be used to calculate the position of the vehicle. However, if not verified, the disclosed techniques can adjust the thresholds used to determine GNSS spoofing and perform additional iterations of integrity monitoring to acquire a verified positioning solution.

Abstract: Techniques for detecting and excluding spoofed Global Navigation Satellite System (GNSS) signals are described. Using position data acquired from inertial sensors, a line of sight (LOS) estimation can be determined to various satellites. This data can be compared with range data provided by a GNSS receiver, for example, by subtracting the LOS estimations with corresponding GNSS ranges. The difference can then be compared to an appropriate threshold to determine whether GNSS spoofing is present. Additionally, the non-spoofed GNSS signals can be used to generate an updated position solution, which is verified by an integrity algorithm. If verified, the updated position solution can be used to calculate the position of the vehicle. However, if not verified, the disclosed techniques can adjust the thresholds used to determine GNSS spoofing and perform additional iterations of integrity monitoring to acquire a verified positioning solution.

Abstract: The present invention provides polypeptide modulators of complement activity, including cyclic polypeptide modulators. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: The present invention provides modulators of complement activity. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: The present invention provides modulators of complement activity. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: The present invention provides Ras modulators including inhibitors and/or antagonists of Ras, Ras binding, and Ras-dependent cell signaling activity. Also provided are methods of utilizing the Ras modulators as therapeutics.

Abstract: The present invention provides polypeptide modulators of complement activity, including cyclic polypeptide modulators. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: A method and device for use in hand gesture recognition is applicable to image processing. The method includes: acquiring a depth map of a hand in a current image; estimating first positions of joints of the hand according to the depth map of the hand; creating a 3D point cloud of the hand according to the depth map of the hand; matching the first position of the joints of the hand and a stored 3D hand model to the 3D point cloud of the hand to obtain second positions of the joints and first degree of freedom parameters of the joints; and recognizing the hand's gestures according to the second positions of the joints and the first degree of freedom parameters of the joints. The method achieves a practical hand gesture recognition technique and recognizes hand gestures accurately.

Abstract: The present invention provides polypeptide modulators of complement activity, including cyclic polypeptide modulators. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: The present invention provides modulators of complement activity. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: The present invention provides polypeptide modulators of complement activity, including cyclic polypeptide modulators. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: A method and apparatus are provided for performing consistency testing for a Bose-Chaudhuri-Hocquenghem (BCH) error corrected first sub-frame of navigation message broadcast from a satellite of a GNSS. Consistency testing is performed by comparing BCH encoded portion(s)s of data symbols with elements of look up table(s) to see if such portions are similar to element(s) of the look up table(s).