Abstract: Disclosed herein are methods of preparing composites from solid elastomer(s) and wet filler(s), as well as products, including composites, vulcanizates, and articles therefrom. The wet filler can have a liquid content of at least 15%. A resulting composite comprises the filler dispersed in the elastomer at a loading of at least 20 phr with a filler yield loss of no more than 10%, wherein the composite has a liquid content of no more than 10% by weight based on total weight of said composite.

Abstract: A process for producing propylene involves dehydration of isopropanol. The dehydration process includes a step of subjecting a starting material containing isopropanol to a dehydration reaction in the presence of a dehydration catalyst comprising alumina to produce a product containing propylene. The starting material has a water content of 0.1 to 10.0 wt % (relative to 100 wt % of the total mass of the starting material), and the product has a total content of C2 unsaturated impurities and C3-C4 unsaturated impurities of 80 ppm or less (relative to 100 wt % of the total mass of the product).

Abstract: A surgical stapling device includes a clamp slide assembly and an end effector that includes a cartridge module. The clamp slide assembly includes a distal portion that defines a curved slot and includes a linear section that defines linear channels. The cartridge module includes a curved module body that includes a linear section that includes linear ribs. The linear ribs are received within the linear channels to facilitate loading of the cartridge module into the distal portion of the clamp slide assembly in a linear fashion.

Abstract: A wear-resistant coating with a low friction coefficient of aluminum titanium nitride-tungsten disulfide (AlTiN—WS2) and a preparation method are provided. The preparation method includes: (1) performing a titanium ion cleaning on a preprocessed substrate by using a titanium ion arc target to obtain a cleaned substrate; (2) depositing a titanium transition coating on the cleaned substrate by using a multi-arc ion plating to obtain a deposited substrate; (3) depositing an aluminum titanium nitride (AlTiN) coating on the deposited substrate by using an AlTi alloy ion arc target to obtain an AlTiN coating substrate; and (4) depositing a titanium coating and a tungsten disulfide (WS2) coating by using a high power impulse magnetron sputtering (HiPIMS) to obtain the wear-resistant coating of AlTiN—WS2. The wear-resistant coating is prepared by pre-depositing the AlTiN solid coating using the multi-arc ion plating, and followed by depositing the WS2 solid lubrication coating using HiPIMS.

Abstract: The present invention relates to chimeric papilloma virus L1 proteins and polynucleotides encoding thereof, and also to HPV virus-like particles and the preparation methods thereof. Said chimeric papilloma virus L1 protein comprises an N-terminal fragment derived from L1 protein of the first papilloma virus type, said N-terminal fragment maintains the immunogenicity of the L1 protein of the corresponding type of HPV; and a C-terminal fragment derived from L1 protein of the second papilloma virus type, said L1 protein of the second papilloma virus type has a better expression level and a better solubility compared to the L1 proteins of other HPV types; wherein said chimeric papilloma virus L1 proteins have the immunogenicity of the L1 proteins of the corresponding HPV types. Said chimeric papilloma virus L proteins have better expression amount and solubility for mass production of vaccines.

Abstract: The present disclosure provides processes for making enantiomerically pure isoxazoline compounds of formula (1), The present disclosure also provides processes for making enantiomerically pure isoxazoline compounds of formula (1) characterized by improving the enantiomeric purity of 3-methyl-5-[(5S)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4H-isoxazol-3-yl]thiophene-2-carboxylic acid by crystallization.

Abstract: The present invention discloses a bridged ring-substituted heteroaryl-pyran derivative and a use thereof, and in particular discloses a compound as represented in formula (VI) or a pharmaceutically acceptable salt thereof.

Abstract: A preparation method for a tungsten sulfide (WS2) solid lubricating film based on high power impulse magnetron sputtering (HiPIMS) is provided. The preparation method includes the following steps: step 1: depositing a metal conductive film on a surface of a WS2 target; step 2: using magnetic field sputtering to remove the metal conductive film in a target sputtering area on the surface of the WS2 target, thereby obtaining a first WS2 target; and step 3: performing the HiPIMS on the first WS2 target to obtain the WS2 solid lubricating film. The preparation method can achieve stable glow discharge of a WS2 target and use the high deposition energy of HiPIMS to prepare the WS2 solid lubricating film with high compactness and excellent wear resistance.

Abstract: In its many embodiments, the present invention provides certain 7-, 8-, and 10-substituted amino triazolo quinazoline derivatives of Formula (I): or a pharmaceutically acceptable salt thereof, wherein ring A, R1, R2, and R4 are as defined herein, pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other therapeutic agents), and methods for their preparation and use, alone and in combination with other therapeutic agents, as antagonists of A2a and/or A2b receptors, and their use in the treatment of a variety of diseases, conditions, or disorders that are mediated, at least in part, by the adenosine A2a receptor and/or the adenosine A2b receptor.

Abstract: Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme: (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.

Abstract: A touch sampling control module, a touch sampling control module method, and a display touch device. The touch sampling control module includes a touch sampling flag generation circuitry and a sampling time control circuitry. The touch sampling flag generation circuitry is configured to generate a touch sampling flag in accordance with a fluctuation time point of a data voltage applied to a touch display panel. The sampling time control circuitry is configured to control a touch sampling time in accordance with the touch sampling flag, so that the touch sampling time is different from the fluctuation time point of the data voltage. The data voltage fluctuates when an absolute value of a voltage change of the data voltage is larger than a voltage change threshold.

Abstract: A circuit board with anti-corrosion properties, a method for manufacturing the circuit board, and an electronic device are provided. The circuit board includes a circuit substrate, a first protective layer, and a second protective layer. The circuit substrate includes a base layer and an outer wiring layer formed on the base layer. The circuit substrate further defines a via hole connected to the outer wiring layer. The first protective layer is formed on the outer wiring layer and an inner sidewall of the via hole, and is made of a white oil. The second protective layer is formed on the first protective layer.

Abstract: An in-situ stress measurement device for ultra-deep non-vertical drilling adopts a technical route of single channel and bidirectional rolling of in-hole equipment, and its related functions are mainly realized by a bidirectional rolling device and a split-type axial-force-free circuit switching valve. The bidirectional rolling device can drive the in-hole equipment to move freely in a circumferential direction and back and forth, which changes sliding friction between the in-hole equipment and a hole wall into rolling friction during an in-situ stress measurement of non-vertical drilling. The split-type axial-force-free circuit switching valve provides a technical solution for a single-pipe test in the non-vertical drilling.

Abstract: The present invention relates to chimeric papilloma virus L1 proteins and polynucleotides encoding thereof, and also to HPV virus-like particles and the preparation methods thereof. Said chimeric papilloma virus L1 protein comprises an N-terminal fragment derived from L1 protein of the first papilloma virus type, said N-terminal fragment maintains the immunogenicity of the L1 protein of the corresponding type of HPV; and a C-terminal fragment derived from L1 protein of the second papilloma virus type, said L1 protein of the second papilloma virus type has a better expression level and a better solubility compared to the L1 proteins of other HPV types; wherein said chimeric papilloma virus L1 proteins have the immunogenicity of the L1 proteins of the corresponding HPV types. Said chimeric papilloma virus L proteins have better expression amount and solubility for mass production of vaccines.

Abstract: An optical waveguide element, including a first optical waveguide, a second optical waveguide, a third optical waveguide, and a grating, is provided. The second optical waveguide is disposed on the first optical waveguide. The third optical waveguide is disposed on the second optical waveguide. The grating is disposed between the first optical waveguide and the second optical waveguide. A refractive index of the second optical waveguide is smaller than a refractive index of the first optical waveguide and a refractive index of the third optical waveguide. A head-mounted display is also provided.

Abstract: Methods and systems for determining a well shut-in pressure of oil and gas well drilling are provided. The method comprises: obtaining, by a first processor, a basic parameter of a target oil and gas well, the basic parameter including at least one of a wellbore structure parameter, a well drilling fluid performance parameter, or a casing string parameter; obtaining, by the first processor, a pressure calculation model; and determining, by the first processor, a maximum well shut-in pressure during well drilling of the target oil and gas well based on the pressure calculation model and the basic parameter.

Abstract: A Lactiplantibacillus plantarum strain ZFM518 deposited under CCTCC NO: M 2022442 is provided. Also provided is a composition including the strain ZFM518. Further provided is a method of treating a subject infected by Klebsiella pneumoniae ZFM4 deposited under CCTCC NO: M 20221900, including administrating to the subject a composition comprising a therapeutically effective amount of a fermentation supernatant of the Lactiplantibacillus plantarum strain ZFM518.

Abstract: A first node receives a first reference signal in a first RS resource; first operates a first signal on a first frequency band; a duplex mode of the first frequency band is a frequency division duplex; the first operating is to receive and the first signal is on a downlink working band, or the first operating is to transmit and the first signal is on an uplink working band; the first signal is spatially associated with the first RS resource; when the first operating is to receive, time-domain resources occupied by the first signal are not overlapping with a first time-domain resource pool; when the first operating is to transmit, time-domain resources occupied by the first signal are not overlapping with a second time-domain resource pool; time-domain resources occupied by the first time-domain resource pool are orthogonal to time-domain resources occupied by the second time-domain resource pool.

Abstract: Provided is an efficient and energy-saving building slurry stirring device. The device includes a grouting assembly, which includes a base, a storage tank, a discharge pipe, a grouting pump and a control box. The storage tank is arranged at the top of the base, the discharge pipe is located at one side of the storage tank, the grouting pump is arranged on the discharge pipe, and the control box is fixed to the top of the base. When the fluidity of a grouting material in the storage tank is reduced due to solidification, the stirring assembly can stir the grouting material in the storage tank. Then, the stirring assembly stops stirring the grouting material to save energy. After the grouting is completed, an inner wall of the storage tank can be cleaned by the stirring assembly.

Abstract: A display panel has an opening region, a display region, and first and second peripheral regions; and includes a substrate, a first barrier structure surrounding the display region and in the first peripheral region, a second barrier structure surrounding the opening region and in the second peripheral region, and a crack detection line including first and second portions. The first portion surrounds the opening region, and is on a side of the second barrier structure distal to the display region. Both ends of the second portion are respectively connected to both ends of the first portion. Orthogonal projections of the second portion and the second barrier structure on the substrate overlap each other. The second portion extends into the first peripheral region through the display region. A height of a portion of the second barrier structure overlapping the second portion is less than that of the first barrier structure.