Abstract: The disclosure discloses a preparation method and application of a non-noble metal single atom catalyst, and belongs to the technical fields of chemistry, chemical engineering and material science. According to the disclosure, cheap raw materials and simple method are used to prepare the single atom catalyst. In essence, metal is anchored on light-absorbing carrier in a single atom form under irradiation to produce the single atom catalyst. In the disclosure, the non-noble metal single atom catalyst is prepared by using a photochemical synthetic route for the first time. The single atom catalyst synthesized in the disclosure is dispersed on the surface of photoactive substance. Using nickel single atom as a co-catalyst in photocatalytic water splitting to produce hydrogen, the cost is low and the catalytic efficiency is greatly improved compared with other types of non-noble metal modified composite photocatalysts.

Abstract: Methods of treating a subject with diabetes or Alzheimer's disease with a disclosed insulin isoform or C? polypeptide are provided. Methods of detecting insulin isoforms or C? polypeptides are also provided.

Abstract: A configuration helper system (CHS) is described that simplifies the task of generating configuration information for a customer premises equipment (CPE) in a customer's on-premise network to enable the CPE to communicate with the customer's cloud network over a particular communication channel. The CHS is configured to generate configuration information that is customized for the particular CPE and communication channel. Given information about the CPE and the communication channel, the CHS automatically identifies a particular set of configuration parameters to be included in the customized configuration information and determines values for the set of parameters, where some of the values may be provided by the customer. A particular CPE-specific format is determined for the configuration information.

Abstract: A configuration helper system (CHS) is described that simplifies the task of generating configuration information for a customer premises equipment (CPE) in a customer's on-premise network to enable the CPE to communicate with the customer's cloud network over a particular communication channel. The CHS is configured to generate configuration information that is customized for the particular CPE and communication channel. Given information about the CPE and the communication channel, the CHS automatically identifies a particular set of configuration parameters to be included in the customized configuration information and determines values for the set of parameters, where some of the values may be provided by the customer. A particular CPE-specific format is determined for the configuration information.

Abstract: A configuration helper system (CHS) is described that simplifies the task of generating configuration information for a customer premises equipment (CPE) in a customer's on-premise network to enable the CPE to communicate with the customer's cloud network over a particular communication channel. The CHS is configured to generate configuration information that is customized for the particular CPE and communication channel. Given information about the CPE and the communication channel, the CHS automatically identifies a particular set of configuration parameters to be included in the customized configuration information and determines values for the set of parameters, where some of the values may be provided by the customer. A particular CPE-specific format is determined for the configuration information.

Abstract: The disclosure discloses a preparation method and application of a non-noble metal single atom catalyst, and belongs to the technical fields of chemistry, chemical engineering and material science. According to the disclosure, cheap raw materials and simple method are used to prepare the single atom catalyst. In essence, metal is anchored on light-absorbing carrier in a single atom form under irradiation to produce the single atom catalyst. In the disclosure, the non-noble metal single atom catalyst is prepared by using a photochemical synthetic route for the first time. The single atom catalyst synthesized in the disclosure is dispersed on the surface of photoactive substance. Using nickel single atom as a co-catalyst in photocatalytic water splitting to produce hydrogen, the cost is low and the catalytic efficiency is greatly improved compared with other types of non-noble metal modified composite photocatalysts.

Abstract: This invention relates to novel phosphorylation sites in cardiac Troponin I that are associated with the onset of heart failure. The phosphorylation sites, i.e., serine 5, tyrosine 26, threonine 51, serine 166, threonine 181 and/or serine 199, can be used as biomarkers for (i) identifying subjects at risk for the development of heart failure, (ii) treating subjects having a higher than normal level of the biomarker, and (iii) monitoring therapy of a subject at risk for the development of heart failure. Also described are antibodies, reagents, and kits for carrying out a method of the present invention.

Abstract: This invention relates to novel phosphorylation sites in cardiac Troponin I that are associated with the onset of heart failure. The phosphorylation sites, i.e., serine 5, tyrosine 26, threonine 51, serine 166, threonine 181 and/or serine 199, can be used as biomarkers for (i) identifying subjects at risk for the development of heart failure, (ii) treating subjects having a higher than normal level of the biomarker, and (iii) monitoring therapy of a subject at risk for the development of heart failure. Also described are antibodies, reagents, and kits for carrying out a method of the present invention.