Patents by Inventor Pingming Tang

Pingming Tang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FIVE-MEMBERED RING DERIVATIVE AND MEDICAL USE THEREOF
    Publication number: 20240124470
    Abstract: A compound represented by general formula (I) or a stereoisomer, tautomer, deuterated substance, solvate, prodrug, metabolite, pharmaceutically acceptable salt or co-crystal thereof, an intermediate thereof and a preparation method therefor, as well as an application in preparation of a drug for treating diabetes.
    Type: Application
    Filed: December 24, 2021
    Publication date: April 18, 2024
    Inventors: Chen ZHANG, Ming LEI, Mingliang ZHAO, Yan YU, Pingming TANG, Guanglin WENG, Tao MOU, Yao LI, Jia NI, Pangke YAN
  • KETOHEXOKINASE INHIBITOR AND USE THEREOF
    Publication number: 20240067633
    Abstract: Provided are a compound of formula (I), a stereoisomer, a deuterated compound, a solvate, a prodrug, a metabolite, a pharmaceutically acceptable salt or a eutectic thereof, or a pharmaceutical composition comprising same, and use thereof as a ketohexokinase inhibitor in the preparation of drugs for treating related diseases. Each group in formula (I) is as defined in the description.
    Type: Application
    Filed: December 21, 2021
    Publication date: February 29, 2024
    Inventors: Yao LI, Wenjing WANG, Lei CHEN, Guobiao ZHANG, Xiaobo ZHANG, Gang HU, Yajun WANG, Haodong WANG, Pingming TANG, Yan YU, Chen ZHANG, Pangke YAN
  • NITRILE DERIVATIVE THAT ACTS AS INHIBITOR OF DIPEPTIDYL PEPTIDASE 1 AND USE THEREOF
    Publication number: 20240059681
    Abstract: Disclosed is a nitrile derivative compound represented by formula (I), a stereoisomer, a deuterated product, a co-crystal, a solvate or a pharmaceutically acceptable salt thereof, wherein each group is as defined in the description. The compound has dipeptidyl peptidase 1 inhibitory activity and can be used to prepare a drug for treating diseases including obstructive airway diseases, bronchiectasis, cystic fibrosis, asthma, emphysema, and chronic obstructive pulmonary diseases.
    Type: Application
    Filed: September 15, 2023
    Publication date: February 22, 2024
    Applicant: HAISCO PHARMACEUTICALS PTE. LTD.
    Inventors: Yao Li, Zongjun Shi, Guobiao ZHANG, Lei Chen, Wenjing Wang, Xiaobo Zhang, Dengyu Zheng, Bo Xu, Xin Liu, Yajun Wang, Fei Ye, Pingming Tang, Jia Ni, Chen Zhang, Pangke Yan
  • SALT AND CRYSTAL FORM OF HA INHIBITOR COMPOUND
    Publication number: 20240043416
    Abstract: Disclosed are a pharmaceutically acceptable salt of an HA inhibitor (1S,2S)-2-fluoro-N-(2-(2-(4-((R)-(5-methyl-2H-tetrazol-2-yl)(phenyl)methyl)piperidine-1-formyl)pyridine-4-yl)benzo[d]oxazol-5-yl)cyclopropyl-1-carboxamide, or a hydrate or solvate of a salt thereof, a preparation method therefor, and a use thereof.
    Type: Application
    Filed: January 27, 2022
    Publication date: February 8, 2024
    Applicant: SICHUAN HAISCO PHARMACEUTICAL CO., LTD.
    Inventors: Yao LI, Guobiao ZHANG, Xiaobo ZHANG, Pingming TANG, Chen ZHANG, Pangke YAN
  • INHIBITOR OF ENHANCER OF ZESTE HOMOLOGUE 2, AND USE THEREOF
    Publication number: 20230365541
    Abstract: Disclosed are a compound of formula (I), a stereoisomer, a pharmaceutically acceptable salt, a solvate, and a eutectic or deuterated compound thereof, or a pharmaceutical composition comprising same, and a use thereof as an EZH2 inhibitor in the preparation of a medication for treating related diseases. The definition of each group in formula (I) is consistent with that in the description.
    Type: Application
    Filed: March 15, 2021
    Publication date: November 16, 2023
    Inventors: Yao LI, Zongjun SHI, Guobiao ZHANG, Wenjing WANG, Lei CHEN, Yunpeng PEI, Long YANG, Changwei SONG, Pingming TANG, Fei YE, Chen ZHANG, Jia NI, Pangke YAN
  • COMPOUND CAPABLE OF INHIBITING AND DEGRADING ANDROGEN RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICAL USES THEREOF
    Publication number: 20230357193
    Abstract: A compound as shown in general formula B-L-K (I) or stereoisomers, deuterated compounds, solvates, prodrugs, metabolites, pharmaceutically acceptable salts or co-crystals thereof, and intermediates thereof and uses thereof for AR-related diseases such as prostate cancer.
    Type: Application
    Filed: July 8, 2021
    Publication date: November 9, 2023
    Inventors: Chen ZHANG, Yuting LIAO, Guozhi ZHU, Fei YE, Xinfan CHENG, Xiaogang CHEN, Pingming TANG, Yao LI, Jia NI, Pangke YAN
  • Nitrile derivative that acts as inhibitor of dipeptidyl peptidase 1 and use thereof
    Patent number: 11807635
    Abstract: Disclosed is a nitrile derivative compound represented by formula (I), a stereoisomer, a deuterated product, a co-crystal, a solvate or a pharmaceutically acceptable salt thereof, wherein each group is as defined in the description. The compound has dipeptidyl peptidase 1 inhibitory activity and can be used to prepare a drug for treating diseases including obstructive airway diseases, bronchiectasis, cystic fibrosis, asthma, emphysema, and chronic obstructive pulmonary diseases.
    Type: Grant
    Filed: October 28, 2022
    Date of Patent: November 7, 2023
    Assignee: Haisco Pharmaceuticals Pte. Ltd.
    Inventors: Yao Li, Zongjun Shi, Guobiao Zhang, Lei Chen, Wenjing Wang, Xiaobo Zhang, Dengyu Zheng, Bo Xu, Xin Liu, Yajun Wang, Fei Ye, Pingming Tang, Jia Ni, Chen Zhang, Pangke Yan
  • COMPOUND HAVING BTK KINASE DEGRADING ACTIVITY, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREFOR
    Publication number: 20230248833
    Abstract: A compound as shown in general formula (I) or stereoisomers, deuterated compounds, solvates, prodrugs, metabolites, pharmaceutically acceptable salts or co-crystals thereof, and intermediates thereof, a preparation method therefor, and a use thereof for treating BTK-related diseases, such as cancer or autoimmune diseases.
    Type: Application
    Filed: July 7, 2021
    Publication date: August 10, 2023
    Inventors: Chen ZHANG, Yuting LIAO, Jianmin WANG, Xinfan CHENG, Xiaogang CHEN, Sijia ZOU, Shuai YUAN, Fei YE, Pingming TANG, Guozhi ZHU, Zhenggang HUANG, Shoutao WU, Yao LI, Jia NI, Pangke YAN
  • NITRILE DERIVATIVE THAT ACTS AS INHIBITOR OF DIPEPTIDYL PEPTIDASE 1 AND USE THEREOF
    Publication number: 20230121807
    Abstract: Disclosed is a nitrile derivative compound represented by formula (I), a stereoisomer, a deuterated product, a co-crystal, a solvate or a pharmaceutically acceptable salt thereof, wherein each group is as defined in the description. The compound has dipeptidyl peptidase 1 inhibitory activity and can be used to prepare a drug for treating diseases including obstructive airway diseases, bronchiectasis, cystic fibrosis, asthma, emphysema, and chronic obstructive pulmonary diseases.
    Type: Application
    Filed: October 28, 2022
    Publication date: April 20, 2023
    Applicant: HAISCO PHARMACEUTICALS PTE. LTD
    Inventors: Yao Li, Zongjun Shi, Guobiao ZHANG, Lei Chen, Wenjing Wang, Xiaobo Zhang, Dengyu Zheng, Bo Xu, Xin Liu, Yajun Wang, Fei Ye, Pingming Tang, Jia Ni, Chen Zhang, Pangke Yan
  • NITROGEN-CONTAINING HETEROCYCLIC AUTOTAXIN INHIBITOR, AND COMPOSITION CONTAINING SAME AND USE THEREOF
    Publication number: 20230069174
    Abstract: Disclosed are a nitrogen-containing heterocyclic compound as shown in formula (I), or a stereoisomer, a solvate, a deuterated form, a pharmaceutically acceptable salt, or a cocrystal thereof or a pharmaceutical composition containing same, and the use thereof in the preparation of a drug for treating/preventing diseases mediated by autotaxin. Each group in formula (I) is as defined in the description.
    Type: Application
    Filed: December 10, 2020
    Publication date: March 2, 2023
    Inventors: Yao LI, Zongjun SHI, Wenjing WANG, Yongli WANG, Yunpeng PEI, Changwei SONG, Yonghong LI, Pingming TANG, Yan YU, Chen ZHANG, Jia NI, Pangke YAN
  • Substituted piperidines as BTK inhibitors
    Patent number: 11542266
    Abstract: Substituted piperidines as BTK inhibitors, a preparation method thereof and a pharmaceutical application thereof. The substituted piperidines is a compound represented by a general formula (I) or a stereoisomer or a pharmaceutically acceptable salt thereof, and the substituted piperidines is used to treat BTK-related diseases such as tumors or autoimmune system diseases.
    Type: Grant
    Filed: October 6, 2021
    Date of Patent: January 3, 2023
    Assignee: HAISCO PHARMACEUTICALS PTE. LTD.
    Inventors: Chen Zhang, Yuting Liao, Jianmin Wang, Guozhi Zhu, Fei Ye, Pingming Tang, Xiaogang Chen, Zhenggang Huang, Shoutao Wu, Yao Li, Pangke Yan