Patents by Inventor Pingping Wang

Pingping Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210000954
    Abstract: A stable anti-PD-1 antibody pharmaceutical preparation and an application thereof in a medicine. The anti-PD-1 antibody pharmaceutical preparation comprises an anti-PD-1 antibody, a buffer, and can further comprise at least one type of stabilizer, and optionally can further con a surfactant. The anti-PD-1 antibody pharmaceutical preparation of the present invention can effectively suppress antibody aggregation and deamidation, thereby preventing degradation of an antibody product, obtaining a stable injected pharmaceutical preparation.
    Type: Application
    Filed: September 2, 2020
    Publication date: January 7, 2021
    Inventors: Jie Li, Zhen Yan, Pingping Wang, Yan Fang, Weikang Tao, Lianshan Zhang, Piaoyang Sun
  • Publication number: 20200385459
    Abstract: The present disclosure generally relates to compositions and methods for cancer immunotherapy, as well as hematopoietic recovery following cancer treatment such as chemotherapy or irradiation.
    Type: Application
    Filed: November 29, 2018
    Publication date: December 10, 2020
    Inventors: Bruce Beutler, Evan Nair-Gill, Xue Zhong, Jinglei Zhang, Pingping Wang
  • Patent number: 10786567
    Abstract: A stable anti-PD-1 antibody pharmaceutical preparation and an application thereof in a medicine. The anti-PD-1 antibody pharmaceutical preparation comprises an anti-PD-1 antibody, a buffer, and can further comprise at least one type of stabilizer, and optionally can further comprise a surfactant. The anti-PD-1 antibody pharmaceutical preparation of the present invention can effectively suppress antibody aggregation and deamidation, thereby preventing degradation of an antibody product, resulting in a stable injectable pharmaceutical preparation.
    Type: Grant
    Filed: September 14, 2016
    Date of Patent: September 29, 2020
    Assignees: Suzhou Suncediabiopharmaeuticals Co., Ltd., Jiangsu Hengrui Medicine Co., Ltd., Shanghai Hengrui Pharmaceutical Co., Ltd.
    Inventors: Jie Li, Zhen Yan, Pingping Wang, Yan Fang, Weikang Tao, Lianshan Zhang, Piaoyang Sun
  • Publication number: 20200255981
    Abstract: A high-stretchable high-sensitive flexible force-sensitive sensing fiber and a preparation method therefor comprising the specific preparation method is as follows: uniformly and synergistically dispersing a one-dimensional (1D) nanowire/nanotube and a two-dimensional (2D) conductive sheet layer in a thermoplastic elastomer solution; formulating a uniform dispersion solution of a certain concentration; and using a wet spinning process to prepare an elastic composite fiber with a highly oriented 1D/2D hybrid network. The above-described composite fiber is placed in a metal precursor solution to fully swell, and then placed in reductive steam for reduction, to reduce metal precursors to zero-dimensional (0D) metal nanoparticles, thereby preparing a flexible force-sensitive sensing fiber based on a 0D/1D/2D three-dimensional collaborative network.
    Type: Application
    Filed: November 27, 2017
    Publication date: August 13, 2020
    Applicant: SOUTH CHINA UNIVERSITY OF TECHNOLOGY
    Inventors: Lan LIU, Song CHEN, Shuqi LIU, Xuchu DONG, Pingping WANG, Haizhou LIU
  • Publication number: 20180339045
    Abstract: A stable anti-PD-1 antibody pharmaceutical preparation and an application thereof in a medicine. The anti-PD-1 antibody pharmaceutical preparation comprises an anti-PD-1 antibody, a buffer, and can further comprise at least one type of stabilizer, and optionally can further comprise a surfactant. The anti-PD-1 antibody pharmaceutical preparation of the present invention can effectively suppress antibody aggregation and deamidation, thereby preventing degradation of an antibody product, resulting in a stable injectable pharmaceutical preparation.
    Type: Application
    Filed: September 14, 2016
    Publication date: November 29, 2018
    Inventors: Jie LI, Zhen YAN, Pingping WANG, Yan FANG, Weikang TAO, Lianshan ZHANG, Piaoyang SUN
  • Patent number: 9976167
    Abstract: Provided are the use of glycosyltransferases gGT25, gGT13, gGT30, gGT25-1, gGT25-3, gGT25-5, gGT29, gGT29-3, gGT29-4, gGT29-5, gGT29-6, gGT29-7, 3GT1, 3GT2, 3GT3, 3GT4 and derived polypeptides therefrom in the catalyzed glycosylation of terpenoid compounds and the synthesis of new saponins, wherein the glycosyltransferases can specifically and efficiently catalyze tetracyclic triterpenoid compound substrates at positions C-20 and/or C-6 and/or C-3 during hydroxyl glycosylation, and/or transfer the glycosyl from a glycosyl donor to the first glycosyl of the tetracyclic triterpenoid compounds at position C-3, so as to extend the sugar chain. The glycosyltransferases can also be used for constructing man-made synthetic rare ginsenosides and a variety of new ginsenosides and derivatives thereof.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: May 22, 2018
    Assignee: Shanghai Institutes For Biological Sciences, Chinese Academy Of Sciences
    Inventors: Zhihua Zhou, Xing Yan, Yun Fan, Pingping Wang, Yongjun Wei, Wei Wei, Jun Zhang
  • Patent number: 9919718
    Abstract: The present invention provides a variable stiffness positioning device for a railway vehicle bogie axle box. The variable stiffness positioning device includes a vertical elastomer arranged between the top face of an axle box bearing saddle and the bottom surface of a guide frame of a side fame, and a longitudinal elastomer arranged between the axle box bearing saddle and the front and back side faces of the guide frame of the side fame, the longitudinal elastomer is provided with at least one small-stiffness elastic element and a large-stiffness elastic element, and the small-stiffness elastic element is arranged in an elastomer pre-compression device and is serially arranged with the large-stiffness elastic element under the action of a pre-compression load F1.
    Type: Grant
    Filed: October 31, 2014
    Date of Patent: March 20, 2018
    Assignee: CRRC Yangtze Corporation Limited
    Inventors: Zhixiong Yan, Ruijin Jiang, Liangwei Zhang, Hong Cui, Fengwei Liu, Wenliang Liu, Tiejun Fu, Zhaojun Dan, Pingping Wang
  • Publication number: 20170129509
    Abstract: The present invention provides a variable stiffness positioning device for a railway vehicle bogie axle box. The variable stiffness positioning device includes a vertical elastomer arranged between the top face of an axle box bearing saddle and the bottom surface of a guide frame of a side fame, and a longitudinal elastomer arranged between the axle box bearing saddle and the front and back side faces of the guide frame of the side fame, the longitudinal elastomer is provided with at least one small-stiffness elastic element and a large-stiffness elastic element, and the small-stiffness elastic element is arranged in an elastomer pre-compression device and is serially arranged with the large-stiffness elastic element under the action of a pre-compression load F1.
    Type: Application
    Filed: October 31, 2014
    Publication date: May 11, 2017
    Inventors: Zhixiong Yan, Ruijin Jiang, Liangwei Zhang, Hong Cui, Fengwei Lui, Wenliang Lui, Tiejun Fu, Zhaojun Dan, Pingping Wang
  • Publication number: 20160115515
    Abstract: Provided are the use of glycosyltransferases gGT25, gGT13, gGT30, gGT25-1, gGT25-3, gGT25-5, gGT29, gGT29-3, gGT29-4, gGT29-5, gGT29-6, gGT29-7, 3GT1, 3GT2, 3GT3, 3GT4 and derived polypeptides therefrom in the catalyzed glycosylation of terpenoid compounds and the synthesis of new saponins, wherein the glycosyltransferases can specifically and efficiently catalyze tetracyclic triterpenoid compound substrates at positions C-20 and/or C-6 and/or C-3 during hydroxyl glycosylation, and/or transfer the glycosyl from a glycosyl donor to the first glycosyl of the tetracyclic triterpenoid compounds at position C-3, so as to extend the sugar chain. The glycosyltransferases can also be used for constructing man-made synthetic rare ginsenosides and a variety of new ginsenosides and derivatives thereof.
    Type: Application
    Filed: December 6, 2013
    Publication date: April 28, 2016
    Applicant: Shanghai Institutes For Biological Sciences, Chinese Academy of Sciences
    Inventors: Zhihua Zhou, Xing Yan, Yun Fan, Pingping Wang, Yongjun Wei, Wei Wei, Jun Zhang
  • Publication number: 20150213797
    Abstract: The present invention discloses a voice recognition system and method, wherein the voice recognition system comprises: a microphone array for receiving a voice signal, converting the voice signal into an analog audio signal, and outputting the analog audio signal to an audio coding circuit; the audio coding circuit for converting the received analog audio signal into a digital audio signal, and outputting the digital audio signal to a main control integrated circuit; a Bluetooth transmitting module for receiving a voice signal, converting the voice signal into a digital audio signal, and sending the digital audio signal to a Bluetooth receiving module via Bluetooth; the Bluetooth receiving module for sending the received digital audio signal to the main control integrated circuit; the main control integrated circuit for selecting the digital audio signal from the audio coding circuit or the digital audio signal from the Bluetooth receiving module to perform recognition.
    Type: Application
    Filed: August 14, 2013
    Publication date: July 30, 2015
    Inventors: Pingping Wang, Yong Qie