Patents by Inventor Piotr Barski

Piotr Barski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230190683
    Abstract: The invention features methods for the treatment of cystinosis and other cysteamine sensitive disorders in a subject including administration of a disulfide convertible to cysteamine in vivo. The methods can include the separate administration of a reducing agent to the subject to increase the bioavailablity and extend the plasma pharmacokinetic profile of the cysteamine produced following administration of the disulfide. The methods permit sustained cysteamine plasma concentrations in a subject.
    Type: Application
    Filed: February 7, 2023
    Publication date: June 22, 2023
    Inventors: Vincent P. STANTON, JR., Patrice P. RIOUX, Piotr BARSKI, Dariusz WITT
  • Patent number: 11612576
    Abstract: The invention features methods for the treatment of cystinosis and other cysteamine sensitive disorders in a subject including administration of a disulfide convertible to cysteamine in vivo. The methods can include the separate administration of a reducing agent to the subject to increase the bioavailablity and extend the plasma pharmacokinetic profile of the cysteamine produced following administration of the disulfide. The methods permit sustained cysteamine plasma concentrations in a subject.
    Type: Grant
    Filed: September 20, 2018
    Date of Patent: March 28, 2023
    Assignee: Thiogenesis Therapeutics, Inc.
    Inventors: Vincent P. Stanton, Jr., Patrice P. Rioux, Piotr Barski, Dariusz Witt
  • Publication number: 20200268692
    Abstract: The invention features methods for the treatment of cystinosis and other cysteamine sensitive disorders in a subject including administration of a disulfide convertible to cysteamine in vivo. The methods can include the separate administration of a reducing agent to the subject to increase the bioavailablity and extend the plasma pharmacokinetic profile of the cysteamine produced following administration of the disulfide. The methods permit sustained cysteamine plasma concentrations in a subject.
    Type: Application
    Filed: September 20, 2018
    Publication date: August 27, 2020
    Inventors: Vincent P. STANTON, Jr., Patrice P. RIOUX, Piotr BARSKI, Dariusz WITT
  • Patent number: 9434667
    Abstract: A method for isolation of 1,3-propanediol from post-fermentation broth is disclosed. The method generally involves the following steps: (1) biomass removal from post-fermentation broth by one of the following methods: ultrafiltration, filtration, centrifugation or sedimentation; (2) 1,3-propanediol extraction with organic solvent mixture containing 2-butanone with high efficiency performed continuously or stepwise; (3) distillation under vacuum to obtain highly pure target product and (4) organic solvent recovery and recycling the solvent back into the process. The method is useful for recovering valuable 1,3-propanediol from aqueous solutions produced by fermentation.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: September 6, 2016
    Assignee: Prochimia Surfaces SP. Z.o.o.
    Inventors: Agnieszka Lindstaedt, Dariusz Witt, Joanna Puzewicz-Barska, Piotr Barski
  • Publication number: 20150259269
    Abstract: A method for isolation of 1,3-propanediol from post-fermentation broth is disclosed. The method generally involves the following steps: (1) biomass removal from post-fermentation broth by one of the following methods: ultrafiltration, filtration, centrifugation or sedimentation; (2) 1,3-propanediol extraction with organic solvent mixture containing 2-butanone with high efficiency performed continuously or stepwise; (3) distillation under vacuum to obtain highly pure target product and (4) organic solvent recovery and recycling the solvent back into the process. The method is useful for recovering valuable 1,3-propanediol from aqueous solutions produced by fermentation.
    Type: Application
    Filed: September 27, 2013
    Publication date: September 17, 2015
    Inventors: Agnieszka Lindstaedt, Dariusz Witt, Joanna Puzewicz-Barska, Piotr Barski