Patents by Inventor Piotr Dubrowski

Piotr Dubrowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systems and methods for automated characterization of genetic heterogeneity in tissue samples
    Patent number: 8559693
    Abstract: Systems and methods for the quantitative automated analysis of pathology samples identify groups of spatially-associated similar cells. Cells may be identified as belonging to a group on the basis of spatial location and biomarkers. In some embodiments the biomarkers are multicolour fluorescence in situ hybridization (FISH) signals. Characteristics of the cells in a group may be combined to provide quantitative FISH results that may compensate for variations and artefacts such as thin sectioning that can result in the loss of information due to damage. In heterogeneous tissue samples, grouping cells can permit quantitative results regarding pathological cells to be extracted despite the presences of infiltrating non pathological cells.
    Type: Grant
    Filed: October 10, 2008
    Date of Patent: October 15, 2013
    Assignees: British Columbia Cancer Agency Branch, The University of British Columbia
    Inventors: Calum Eric MacAulay, Piotr Dubrowski, Martial Guillaud, Mehrnoush Khojasteh
  • SYSTEMS AND METHODS FOR AUTOMATED CHARACTERIZATION OF GENETIC HETEROGENEITY IN TISSUE SAMPLES
    Publication number: 20100290692
    Abstract: Systems and methods for the quantitative automated analysis of pathology samples identify groups of spatially-associated similar cells. Cells may be identified as belonging to a group on the basis of spatial location and biomarkers. In some embodiments the biomarkers are multicolour fluorescence in situ hybridization (FISH) signals. Characteristics of the cells in a group may be combined to provide quantitative FISH results that may compensate for variations and artefacts such as thin sectioning that can result in the loss of information due to damage. In heterogeneous tissue samples, grouping cells can permit quantitative results regarding pathological cells to be extracted despite the presences of infiltrating non pathological cells.
    Type: Application
    Filed: October 10, 2008
    Publication date: November 18, 2010
    Applicants: BRITISH COLUMBIA CANCER AGENCY BRANCH, THE UNIVERSITY OF BRITISH COLUMBIA
    Inventors: Calum Eric Macaulay, Piotr Dubrowski, Martial Guillaud