Patents by Inventor Piotr Jachimczak

Piotr Jachimczak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION FOR USE IN A METHOD OF TREATING CANCER
    Publication number: 20170216401
    Abstract: The present invention refers to a combination of a TGF-beta inhibitor selected from the group consisting of an ALK-5 inhibitor, a neutralizing pan-anti-TGF-beta antibody, a neutralizing antibody against TGF-beta-1, or/and -2, or/and -3, a neutralizing anti-TGF-beta receptor type I or/and type II or/and type III antibody or binding fragments thereof with IL-2 and GM-CSF for use in a method of treating a malignant tumor in a patient. The invention is further directed to a pharmaceutical composition comprising the combination of the present invention, wherein the combination of compounds as well as the pharmaceutical composition are administered intratumorally. The combination as well as the pharmaceutical composition further comprise optionally an inhibitor of TGF-beta synthesis.
    Type: Application
    Filed: March 17, 2015
    Publication date: August 3, 2017
    Inventor: Piotr JACHIMCZAK
  • METHOD FOR INHIBITING "MELANOMA INHIBITORY ACTIVITY" MIA
    Publication number: 20120208774
    Abstract: The present invention is directed to peptides, antibodies and antibody fragments inhibiting activity of “Melanoma Inhibitory Activity” (MIA).
    Type: Application
    Filed: February 27, 2012
    Publication date: August 16, 2012
    Inventors: Anja-Katrin Bosserhoff, Reinhard Buettner, Mara Szyrach, Guenter Auerbach, Piotr Jachimczak, Karl-Hermann Schlingensiepen
  • Method for inhibiting “melanoma inhibitory activity” MIA
    Patent number: 8148493
    Abstract: The present invention is directed to peptides, antibodies and antibody fragments inhibiting activity of “Melanoma Inhibitory Activity” (MIA).
    Type: Grant
    Filed: October 21, 2008
    Date of Patent: April 3, 2012
    Assignee: Antisense Pharma GmbH
    Inventors: Anja-Katrin Bosserhoff, Reinhard Buettner, Mara Szyrach, Guenter Auerbach, Piotr Jachimczak, Karl-Hermann Schlingensiepen
  • Method for inhibiting "Melanoma Inhibitory Activity" MIA
    Publication number: 20100273705
    Abstract: The present invention is directed to peptides, antibodies and antibody fragments inhibiting activity of “Melanoma Inhibitory Activity” (MIA).
    Type: Application
    Filed: October 21, 2008
    Publication date: October 28, 2010
    Inventors: Anja-Katrin Bosserhoff, Reinhard Buettner, Mara Szyrach, Guenter Auerbach, Piotr Jachimczak, Karl-Hermann Schlingensiepen
  • Pharmaceutical composition
    Publication number: 20070155685
    Abstract: The present invention is related to pharmaceutical compositions for the inhibition of metastases and treatment of cancer such as bladder carcinoma, colon cancer, endometrial cancer, hepatocellular carcinoma, leukemia, lymphoma, melanoma, non-small cell lung cancer (NSCLC), ovarian cancer, pancreatic cancer, prostate cancer, soft tissue cancer, renal cancer, osteosarcoma, mesothelioma, myeloma multiple, bladder carcinoma and esophagcal cancer as well as the use of these pharmaceutical compositions for the treatment of said metastases and cancers. Another aspect of this invention are new antisense oligonucleotides inhibiting the formation of human interleukin 10 and their synthesis. A further aspect of this invention is the use IL-10 antisense oligonucleotides for the preparation of pharmaceutical compositions and for the treatment of cancer and metastases.
    Type: Application
    Filed: February 28, 2005
    Publication date: July 5, 2007
    Inventors: Karl-Hermann Schlingensiepen, Relmar Schlingensiepen, Piotr Jachimczak, Gerhard Stauder, Astrid Bischof, Michael Hafner, Tamara Egger
  • Method for reversing the immunosuppressive effects of the melanoma inhibitory activity "mia"
    Publication number: 20060252716
    Abstract: A method for stimulating immune cells and/or the immune system, and/or reducing invasion and/or metastasis of tumor cells by inhibiting expression and/or functional activity of “Melanoma Inhibitory Activity” MIA.
    Type: Application
    Filed: March 10, 2001
    Publication date: November 9, 2006
    Inventors: Karl-Hermann Schlingensiepen, Reimar Schlingensiepen, Rainer Apfel, Wolfgang Brysch, Piotr Jachimczak, Ulrich Bogdahn
  • Method for inhibiting "melanoma inhibitory activity" mia
    Publication number: 20060128607
    Abstract: The present invention is directed to peptides, antibodies and antibody fragments inhibiting activity of “Melanoma Inhibitory Activity” (MIA).
    Type: Application
    Filed: January 29, 2002
    Publication date: June 15, 2006
    Inventors: Anja-Katrin Bosserhoff, Reinhard Buettner, Mara Szyrach, Guenther Auerbach, Piotr Jachimczak, Karl-Hermann Schlingensiepen