Patents by Inventor Piotr Koprowski

Piotr Koprowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9309575
    Abstract: The subject of the present invention are mutant strains of Escherichia coli MG6165 (ATCC nr 47076) lacking all potassium transporters: Kdp, Kup and Trk (?Ktrans), encompassing strains lacking at least one of the genes encoding mechanically gated channels mscS and mscL (?Ktrans ?mscS i/lub ?mscL). In particular, it concerns Escherichia coli MG61655 (ATCC No. 47076) lacking all potassium transporters: Kdp, Kup and Trk (?Ktrans), which additionally are devoid of the mechanically gated channel gene mscS—E. coli (?Ktrans ?mscS), the mechanically gated channel gene mscL—E. coli (?Ktrans ?mscL) and/or both the mechanically gated channel genes mscS and mscL—E. coli (?Ktrans ?mscS ?mscL). The subject of the present invention is also a method of testing chemical compounds for potential antibacterial properties, making use of the abovementioned strains. Another subject of the present invention is a kit for testing chemical compounds as potential antibacterial substances, containing the abovementioned strains.
    Type: Grant
    Filed: April 23, 2011
    Date of Patent: April 12, 2016
    Assignee: Instytut Biologii Doswiadczalnej IM. M. Nenckiego Pan
    Inventors: Piotr Koprowski, Andrzej Kubalski, Wojciech Grajkowski
  • Publication number: 20130040336
    Abstract: The subject of the present invention are mutant strains of Escherichia coli MG6165 (ATCC nr 47076) lacking all potassium transporters: Kdp, Kup and Trk (?Ktrans), encompassing strains lacking at least one of the genes encoding mechanically gated channels mscS and mscL (?Ktrans ?mscS i/lub ?mscL). In particular, it concerns Escherichia coli MG61655 (ATCC No. 47076) lacking all potassium transporters: Kdp, Kup and Trk (?Ktrans), which additionally are devoid of the mechanically gated channel gene mscS—E. coli (?Ktrans ?mscS), the mechanically gated channel gene mscL—E. coli (?Ktrans ?mscL) and/or both the mechanically gated channel genes mscS and mscL—E. coli (?Ktrans ?mscS ?mscL). The subject of the present invention is also a method of testing chemical compounds for potential antibacterial properties, making use of the abovementioned strains. Another subject of the present invention is a kit for testing chemical compounds as potential antibacterial substances, containing the abovementioned strains.
    Type: Application
    Filed: April 23, 2011
    Publication date: February 14, 2013
    Applicant: Instytut Biologh Doswiadczalnejim. M. Nenckiego Pa
    Inventors: Piotr Koprowski, Andrzej Kubalski, Wojciech Grajkowski