Patents by Inventor Piotr Marcin Zien

Piotr Marcin Zien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AQUEOUS PHARMACEUTICAL FORMULATIONS
    Publication number: 20220118088
    Abstract: The present invention belong to the field of biotechnology, in particular to the field of galenics. The present invention is directed to an aqueous pharmaceutical composition comprising 1-50 mg/ml of a human or humanized full length IgG4, e.g. natalizumab, and a formulation selected from (i) to (iii), as further defined in the claims. The present invention is further directed to a method for producing said pharmaceutical composition, and medical uses thereof. Finally, also provided is a method for stabilizing human or humanized full length IgG4, e.g. natalizumab, as further defined in the claims.
    Type: Application
    Filed: May 19, 2021
    Publication date: April 21, 2022
    Applicant: POLPHARMA BIOLOGICS S.A.
    Inventors: Dariusz Mateusz Suchy, Malgorzata Bozena Tracka, Kornelia Bogumila Wisniewska, Michael Josef Safinowski, Klemen Spaninger, Piotr Marcin Zien
  • AQUEOUS PHARMACEUTICAL FORMULATIONS
    Publication number: 20210283252
    Abstract: The present invention belong to the field of biotechnology, in particular to the field of galenics. The present invention is directed to an aqueous pharmaceutical composition comprising 1-50 mg/ml of a human or humanized full length IgG4, e.g. natalizumab, and a formulation selected from (i) to (iii), as further defined in the claims. The present invention is further directed to a method for producing said pharmaceutical composition, and medical uses thereof. Finally, also provided is a method for stabilizing human or humanized full length IgG4, e.g. natalizumab, as further defined in the claims.
    Type: Application
    Filed: May 19, 2021
    Publication date: September 16, 2021
    Inventors: Dariusz Mateusz Suchy, Malgorzata Bozena Tracka, Kornelia Bogumila Wisniewska, Michael Josef Safinowski, Klemen Spaninger, Piotr Marcin Zien
  • AQUEOUS PHARMACEUTICAL FORMULATIONS
    Publication number: 20190374639
    Abstract: The present invention belong to the field of biotechnology, in particular to the field of galenics. The present invention is directed to an aqueous pharmaceutical composition comprising 1-50 mg/ml of a human or humanized full length IgG4, e.g. natalizumab, and a formulation selected from (i) to (iii), as further defined in the claims. The present invention is further directed to a method for producing said pharmaceutical composition, and medical uses thereof. Finally, also provided is a method for stabilizing human or humanized full length IgG4, e.g. natalizumab, as further defined in the claims.
    Type: Application
    Filed: November 21, 2017
    Publication date: December 12, 2019
    Inventors: Dariusz Mateusz Suchy, Malgorzata Bozena Tracka, Kornelia Bogumila Wisniewska, Michael Josef Safinowski, Klemen Spaninger, Piotr Marcin Zien
  • RECOMBINANT PRODUCTION OF MONOCLONAL ANTIBODIES
    Publication number: 20190225694
    Abstract: The present invention is directed to a cell culture obtainable from CHO DG44 cells which are capable of being cultured under serum-free or protein-free culture conditions, and which express a biosimilar antibody for the monoclonal antibody natalizumab. The present invention is further directed to a cell of said cell culture, a method for producing said biosimilar antibody, and the use of said cell in said method.
    Type: Application
    Filed: June 27, 2017
    Publication date: July 25, 2019
    Inventors: Piotr Marcin Zien, Matthew Christopher Cheeks, Tomasz Sitar, Kornelia Bogumila Wisniewska, Rafal Andrzej Derlacz