Patents by Inventor Piotr MROZ

Piotr MROZ has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aqueously soluble and chemically stable glucagon peptides
    Patent number: 10683334
    Abstract: Modified glucagon peptides are disclosed having improved solubility and/or stability while retaining glucagon agonist activity. The glucagon peptides have been modified by the substitution of pyridyl-alanine for a native amino acid at one or more of positions 6, 10 or 13 and/or substitution with an amino acid in the D-conformation at position 20 or 21 compared to native glucagon.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: June 16, 2020
    Assignee: Indiana University Research and Technology Corporation
    Inventors: Richard D. Dimarchi, John P. Mayer, Piotr Mroz
  • AQUEOUSLY SOLUBLE & CHEMICALLY STABLE GLUCAGON PEPTIDES
    Publication number: 20190218268
    Abstract: Modified glucagon peptides are disclosed having improved solubility and/or stability while retaining glucagon agonist activity. The glucagon peptides have been modified by the substitution of pyridyl-alanine for a native amino acid at one or more of positions 6, 10 or 13 and/or substitution with an amino acid in the D-conformation at position 20 or 21 compared to native glucagon.
    Type: Application
    Filed: May 31, 2017
    Publication date: July 18, 2019
    Inventors: Richard D. DIMARCHI, John P. MAYER, Piotr MROZ