Patents by Inventor Piotr Pawel Ruchala

Piotr Pawel Ruchala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-obesity compounds derived from neuromedin U
    Patent number: 10155798
    Abstract: The invention relates to polypeptides referred to herein as NMU analog peptides. NMU analog peptides regulate energy homeostasis.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: December 18, 2018
    Assignee: The Regents of the University of California
    Inventors: Piotr Pawel Ruchala, Ewa Dorota Micewicz
  • Anti-Obesity Compounds Derived from Neuromedin U
    Publication number: 20170037103
    Abstract: The invention relates to polypeptides referred to herein as NMU analog peptides. NMU analog peptides regulate energy homeostasis.
    Type: Application
    Filed: December 19, 2014
    Publication date: February 9, 2017
    Applicant: The Regents of the University of California
    Inventors: Piotr Pawel Ruchala, Ewa Dorota Micewicz
  • Modification of peptides using a bis(thioether)arylbridge approach
    Patent number: 9556229
    Abstract: This invention provides novel methods of stabilizing peptides and peptides so stabilized. In certain embodiments the methods involve providing a peptide containing at least two S bearing residues within the peptide; and reacting the peptide with a di-halogen-aryl-compounds to form a bis(thioether)-aryl-bridge between said two residues.
    Type: Grant
    Filed: May 17, 2013
    Date of Patent: January 31, 2017
    Assignee: The Regents of the University of California
    Inventors: Piotr Pawel Ruchala, Ewa Dorota Micewicz
  • MODIFICATION OF PEPTIDES USING A BIS(THIOETHER)ARYLBRIDGE APPROACH
    Publication number: 20150133633
    Abstract: This invention provides novel methods of stabilizing peptides and peptides so stabilized. In certain embodiments the methods involve providing a peptide containing at least two S bearing residues within the peptide; and reacting the peptide with a di-halogen-aryl-compounds to form a bis(thioether)-aryl-bridge between said two residues.
    Type: Application
    Filed: May 17, 2013
    Publication date: May 14, 2015
    Inventors: Piotr Pawel Ruchala, Ewa Dorota Micewicz
  • ANTIVIRAL PEPTIDES EFFECTIVE AGAINST HEPATITIS C VIRUS
    Publication number: 20140294942
    Abstract: In certain embodiments this invention provides novel antiviral peptide(s) that are effective against positive sense RNA viruses that have an internal ribosome entry site (IRES). The peptide(s) can be used to inhibit propagation of such viruses and thereby provide a effective modality for the treatment of infections such as hepatitis C, and the like.
    Type: Application
    Filed: September 6, 2012
    Publication date: October 2, 2014
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Samuel Wheeler French, Ronik Khachatoorian, Piotr Pawel Ruchala
  • Mini-hepcidin peptides and methods of using thereof
    Patent number: 8435941
    Abstract: Disclosed herein are peptides which exhibit hepcidin activity and methods of making and using thereof.
    Type: Grant
    Filed: December 4, 2009
    Date of Patent: May 7, 2013
    Assignee: The Regents of the University of California
    Inventors: Tomas Ganz, Elizabeta Nemeth, Gloria Preza, Piotr Pawel Ruchala