Patents by Inventor Piotr TRZONKOWSKl

Piotr TRZONKOWSKl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210348126
    Abstract: The invention relates to a new method for in vitro expansion of CD4+CD25HighCD127?/LowFoxP3+ Tregs, wherein the process of Treg expansion takes place permanently or temporarily at a temperature below 37° C., optimally at a temperature of 33° C., the isolated Tregs are expanded in SCGM or X-vivo-20 medium supplemented with human serum or with foetal bovine serum, and magnetic beads coated with anti-CD3 and anti-CD28 antibodies at 1:1 (cell:bead) ratio and interleukin-2 are added to the culture.
    Type: Application
    Filed: July 21, 2021
    Publication date: November 11, 2021
    Inventors: Natalia MAREK-TRZONKOWSKA, Piotr TRZONKOWSKl, Malgorzata MYSLIWIEC
  • Publication number: 20180362928
    Abstract: The invention relates to a new method for in vitro expansion of CD4+CD25HighCD127?/LOWfoxP3+Tregs, wherein the process of Treg expansion takes place permanently or temporarily at a temperature below 37° C., optimally at a temperature of 33° C., the isolated Tregs are expanded in SCGM or X-vivo-20 medium supplemented with human serum or with foetal bovine serum, and magnetic beads coated with anti-CD3 and anti-CD28 antibodies at 1:1 (cell:bead) ratio and interleukin-2 are added to the culture.
    Type: Application
    Filed: December 19, 2016
    Publication date: December 20, 2018
    Inventors: Natalia MAREK-TRZONKOWSKA, Piotr TRZONKOWSKl, Malgorzata MYSLIWIEC