Patents by Inventor Pirje Hütt

Pirje Hütt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10272122
    Abstract: A microorganism strain Lactobacillus plantarum Inducia DSM 21379 for use as hypocholesterolemic, antimicrobial and anti-oxidative agent and as enhancer of the natural defense potential of a subject. L. plantarum Inducia is used for reducing the level of LDL-cholesterol in blood for preventing the cholesterol metabolism disorders and cardiovascular disorders. L. plantarum Inducia enhances simultaneously the natural defense potential and cellular immunity, and as anti-oxidative agent enhances anti-oxidative activity of blood by reducing the level of oxidized low density lipoprotein (ox-LDL). The strain is also used as an antimicrobial agent for lowering risk of Clostridium difficile associated diarrhea (CDAD) by preventing germination of C. difficile spores and by suppressing proliferation of its vegetative cells. The compositions comprising L. plantarum Inducia decrease the levels of LDL-cholesterol and ox-LDL in blood, enhance the natural defense potential and lower risk of CDAD.
    Type: Grant
    Filed: April 19, 2016
    Date of Patent: April 30, 2019
    Assignee: BIOCC OÜ
    Inventors: Marika Mikelsaar, Epp Songisepp, Pirje Hütt, Imbi Smidt, Kai Truusalu, Merle Rätsep, Siiri Koljalg, Jelena Stsepetova, Kalle Kilk, Mihkel Zilmer, Epp Sepp, Raik-Hiio Mikelsaar
  • Patent number: 9974817
    Abstract: The invention provides a composition comprising Lactobacillus fermentum ME-3 strain DSM 14241 for use in preventing, alleviating the symptoms of or treating, alone or as an adjuvant component, a metabolic syndrome related disorder selected from prediabetes, type 2 diabetes and cardiovascular disease. The effect may be achieved by simultaneously: decreasing the level of glycated haemoglobin HbA1c, decreasing or preventing low-grade inflammation on a cellular level and increasing the level of adiponectin.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: May 22, 2018
    Assignee: UNIVERSITY OF TARTU
    Inventors: Tiiu Kullisaar, Mihkel Zilmer, Imbi Smidt, Kersti Zilmer, Marika Mikelsaar, Pirje Hütt
  • Publication number: 20160296570
    Abstract: A microorganism strain Lactobacillus plantarum Inducia DSM 21379 for use as hypocholesterolemic, antimicrobial and anti-oxidative agent and as enhancer of the natural defense potential of a subject. L. plantarum Inducia is used for reducing the level of LDL-cholesterol in blood for preventing the cholesterol metabolism disorders and cardiovascular disorders. L. plantarum Inducia enhances simultaneously the natural defense potential and cellular immunity, and as anti-oxidative agent enhances anti-oxidative activity of blood by reducing the level of oxidized low density lipoprotein (ox-LDL). The strain is also used as an antimicrobial agent for lowering risk of Clostridium difficile associated diarrhoeae (CDAD) by preventing germination of C. difficile spores and by suppressing proliferation of its vegetative cells. The compositions comprising L. plantarum Inducia decrease the levels of LDL-cholesterol and ox-LDL in blood, enhance the natural defense potential and lower risk of CDAD.
    Type: Application
    Filed: April 19, 2016
    Publication date: October 13, 2016
    Applicant: TERVISLIKU PllMA BIOTEHNOLOOGIATE ARENDUSKESKUS OÜ (BIO-COMPETENCE CENTRE OF
    Inventors: Marika Mikelsaar, Epp Songisepp, Pirje Hütt, lmbi Smidt, Kai Truusalu, Merle Rätsep, Siiri Koljalg, Jelena Stsepetova, Kalle Kilk, Mihkel Zilmer, Epp Sepp, Raik-Hiio Mikelsaar
  • Publication number: 20150343003
    Abstract: The invention provides a composition comprising Lactobacillus fermentum ME-3 strain DSM 14241 for use in preventing, alleviating the symptoms of or treating, alone or as an adjuvant component, a metabolic syndrome related disorder selected from prediabetes, type 2 diabetes and cardiovascular disease. The effect may be achieved by simultaneously: decreasing the level of glycated haemoglobin HbA1c, decreasing or preventing low-grade inflammation on a cellular level and increasing the level of adiponectin.
    Type: Application
    Filed: December 20, 2013
    Publication date: December 3, 2015
    Inventors: Tiiu Kullisaar, Mihkel Zilmer, Imbi Smidt, Kersti Zilmer, Marika Mikelsaar, Pirje Hütt
  • Publication number: 20140335066
    Abstract: A microorganism strain Lactobacillus plantarum Inducia DSM 21379 for use as hypocholesterolemic, antimicrobial and anti-oxidative agent and as enhancer of the natural defense potential of a subject. L. plantarum Inducia is used for reducing the level of LDL-cholesterol in blood for preventing the cholesterol metabolism disorders and cardiovascular disorders. L. plantarum Inducia enhances simultaneously the natural defense potential and cellular immunity, and as anti-oxidative agent enhances anti-oxidative activity of blood by reducing the level of oxidized low density lipoprotein (ox-LDL). The strain is also used as an antimicrobial agent for lowering risk of Clostridium difficile associated diarrhoeae (CDAD) by preventing germination of C. difficile spores and by suppressing proliferation of its vegetative cells. The compositions comprising L. plantarum Inducia decrease the levels of LDL-cholesterol and ox-LDL in blood, enhance the natural defense potential and lower risk of CDAD.
    Type: Application
    Filed: April 3, 2014
    Publication date: November 13, 2014
    Applicant: TERVISLIKU PIIMA BIOTEHNOLOOGIATE ARENDUSKESKUS OÜ (BIO-COMPETENCE CENTRE OF
    Inventors: Marika Mikelsaar, Epp Songisepp, Pirje Hütt, Imbi Smidt, Kai Truusalu, Merle Rätsep, Siiri Kõljalg, Jelena Stsepetova, Kalle Kilk, Mihkel Zilmer, Epp Sepp, Raik-Hiio Mikelsaar
  • Publication number: 20140328814
    Abstract: The present invention relates to an antimicrobial and antihypertensive probiotic compositions comprising microorganism strain Lactobacillus plantarum Tensia DSM 21380, e.g. food or pharmaceutical compositions or a dietary supplement compositions, food products (dairy products, e.g. fermented products or cheese). The invention also relates to method for suppressing pathogens and non-starter lactobacilli in food product and method for extension of shelf life of food product by the means of Lactobacillus plantarum Tensia DSM 21380.
    Type: Application
    Filed: June 12, 2014
    Publication date: November 6, 2014
    Applicant: Oü Tervisliku Piima Biotehnoloogiate Arenduskeskus (Bio-Competence Centre of
    Inventors: Epp Songisepp, Marika Mikelsaar, Merle Rätsep, Mihkel Zilmer, Pirje Hütt, Meeme Utt, Kristi Zilmer, Janne Uksti, Siiri Kõljalg