Patents by Inventor Pius Hermann

Pius Hermann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12600515
    Abstract: A method for monitoring the sealing of a container in a system or device is described. The method includes the following steps: controlling the heating element to heat a heating stamp to a predetermined sealing temperature, monitoring the temperature of the heating stamp, determining a temperature over time curve of the heating stamp by means of at least one temperature sensor, determining at least one characteristic of the temperature over time curve, comparing the determined at least one characteristic of the temperature over time curve with a reference value, and determining a sealing property of the sealing of the container based on said comparison of the determined at least one characteristic of the temperature over time curve with the reference value.
    Type: Grant
    Filed: November 16, 2023
    Date of Patent: April 14, 2026
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Paul Federer, Pius Hermann, Stefan Vollenweider
  • Patent number: 12544760
    Abstract: A method to monitor and control the temperature of a sample holder of a laboratory instrument during execution of a temperature profile on the sample holder is presented. The laboratory instrument comprises a sample holder with high temperature uniformity and at least three identical temperature sensors. The measured actual temperatures of the sample holder are processed in order to determine if the execution of the temperature profile should be continued or aborted. Furthermore, temperature sensors which measure actual temperatures that do not fulfil certain requirements are excluded from further monitoring and controlling the temperature of a sample holder.
    Type: Grant
    Filed: December 5, 2022
    Date of Patent: February 10, 2026
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Sven Ebert, Paul Federer, Pius Hermann, Stefan Vollenweider
  • Publication number: 20240158118
    Abstract: A method for monitoring the sealing of a container in a system or device is described. The method includes the following steps: controlling the heating element to heat a heating stamp to a predetermined sealing temperature, monitoring the temperature of the heating stamp, determining a temperature over time curve of the heating stamp by means of at least one temperature sensor, determining at least one characteristic of the temperature over time curve, comparing the determined at least one characteristic of the temperature over time curve with a reference value, and determining a sealing property of the sealing of the container based on said comparison of the determined at least one characteristic of the temperature over time curve with the reference value.
    Type: Application
    Filed: November 16, 2023
    Publication date: May 16, 2024
    Inventors: Paul Federer, Pius Hermann, Stefan Vollenweider
  • Publication number: 20230258676
    Abstract: A method for introducing a sample rack holding a plurality of sample receptacles into a receiving bay in a housing of an automated analytical system is disclosed. The method is carried out by manually moving the sample rack from a loading position towards a processing position along a lane in the receiving bay, pausing the movement when the rack reaches a focusing position, moving a reader to focuse onto the lane, resuming the movement of the sample rack and detecting features of the sample rack during the movement, positioning, detecting, and locking the sample rack in the processing position, and processing the content of the sample receptacles.
    Type: Application
    Filed: November 17, 2022
    Publication date: August 17, 2023
    Inventors: Fabian Baggio, Roman Egli, Christian Ettel, Raphael Gut, Pius Hermann, Nikifor Korjagin, Alexander Meier, Thomas Schlaubitz, Rolf Schneebeli, Simon Siegenthaler, Ivo Daniel Vicente Leitao, Stefan Vollenweider
  • Publication number: 20230152342
    Abstract: A method for detection of a bottom of a well of a multiwell plate for a pipetting device is disclosed. The pipetting device includes a pipetting head configured for being coupled to a plurality of pipetting tips. A force sensor configured for measuring a resistance force depending on a force on a pipetting tip exerted by the bottom is used. The method includes measuring the resistance force during movement of one of the pipetting tips from a start position downstream towards the bottom of the well and stopping the movement at a bottom position. The method further includes storing the bottom position together with a corresponding logical position of the well in the multiwell plate in a database. Further disclosed is a pipetting device, a laboratory instrument for processing and/or analyzing a sample and a computer program and a computer-readable storage medium for performing the method.
    Type: Application
    Filed: November 17, 2022
    Publication date: May 18, 2023
    Inventors: Raphael Gut, Pius Hermann, Alexander Meier, Patrick Birkner, Christian Ettel, Roger Spescha, Pengfei Wang, Simon Durrer
  • Publication number: 20230094049
    Abstract: A method to monitor and control the temperature of a sample holder of a laboratory instrument during execution of a temperature profile on the sample holder is presented. The laboratory instrument comprises a sample holder with high temperature uniformity and at least three identical temperature sensors. The measured actual temperatures of the sample holder are processed in order to determine if the execution of the temperature profile should be continued or aborted. Furthermore, temperature sensors which measure actual temperatures that do not fulfil certain requirements are excluded from further monitoring and controlling the temperature of a sample holder.
    Type: Application
    Filed: December 5, 2022
    Publication date: March 30, 2023
    Inventors: Sven Ebert, Paul Federer, Pius Hermann, Stefan Vollenweider
  • Patent number: 11517905
    Abstract: A method to monitor and control the temperature of a sample holder of a laboratory instrument during execution of a temperature profile on the sample holder is presented. The laboratory instrument comprises a sample holder with high temperature uniformity and at least three identical temperature sensors. The measured actual temperatures of the sample holder are processed in order to determine if the execution of the temperature profile should be continued or aborted. Furthermore, temperature sensors which measure actual temperatures that do not fulfil certain requirements are excluded from further monitoring and controlling the temperature of a sample holder.
    Type: Grant
    Filed: July 18, 2019
    Date of Patent: December 6, 2022
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Sven Ebert, Paul Federer, Pius Hermann, Stefan Vollenweider
  • Patent number: 10996233
    Abstract: A laboratory sample distribution system comprising a transport plane in which the transport plane is covered by an electrically conductive material is presented. A laboratory automation system comprising such a laboratory sample distribution system is also presented.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: May 4, 2021
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Pius Hermann, Jonathan Baer
  • Patent number: 10605819
    Abstract: A transport device for a laboratory sample distribution system is presented. The transport device comprises a plurality of electro-magnetic actuators and a driving surface arranged above the actuators, in which the driving surface is configured to carry sample container carriers. The driving surface is tiled and comprises a plurality of driving surface modules with driving surface elements. Support elements arranged in a grid pattern are provided. Each driving surface module is detachably mounted to a subset of the support elements. A laboratory sample distribution system and to a laboratory automation system comprising a laboratory sample distribution system are also presented.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: March 31, 2020
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Marcel Kaeppeli, Tobias Huber, Pius Hermann, Matthias Edelmann
  • Patent number: 10578632
    Abstract: A transport device unit for a transport device assembled using a plurality of transport device units is presented. The transport device unit comprises a base plate module with a base plate for fixing the transport device unit to a support frame, an actuator module with a plurality of electro-magnetic actuators, where the actuator module is supported by the base plate module, and a driving surface module with a driving surface element, where the driving surface element is arranged above the actuator module covering the actuators and configured to carry sample container carriers. A transport device, a system for at least partially disassembling the transport device, and a laboratory sample distribution system comprising a transport device are also presented. In addition, a laboratory automation system comprising a laboratory sample distribution system is also presented.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: March 3, 2020
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Hans Schneider, Eugen Lusser, Marcel Kaeppeli, Tobias Huber, Pius Hermann, Matthias Edelmann
  • Publication number: 20200030807
    Abstract: A method to monitor and control the temperature of a sample holder of a laboratory instrument during execution of a temperature profile on the sample holder is presented. The laboratory instrument comprises a sample holder with high temperature uniformity and at least three identical temperature sensors. The measured actual temperatures of the sample holder are processed in order to determine if the execution of the temperature profile should be continued or aborted. Furthermore, temperature sensors which measure actual temperatures that do not fulfil certain requirements are excluded from further monitoring and controlling the temperature of a sample holder.
    Type: Application
    Filed: July 18, 2019
    Publication date: January 30, 2020
    Inventors: Sven Ebert, Paul Federer, Pius Hermann, Stefan Vollenweider
  • Patent number: 10520520
    Abstract: A transport device for a laboratory sample distribution system is presented. The transport device comprises a plurality of actuator modules. Each actuator module comprises a plurality of electro-magnetic actuators. A plurality of base plate modules arranged in a pattern is provided. The base plate modules are coupled to each other and aligned by support elements. The number of base plate modules at least equals the number of actuator modules and each base plate module is configured to support one of the plurality of actuator modules. A laboratory sample distribution system and to a laboratory automation system comprising a laboratory sample distribution system are also presented.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: December 31, 2019
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Marcel Kaeppeli, Tobias Huber, Pius Hermann, Matthias Edelmann
  • Publication number: 20190239975
    Abstract: The present disclosure relates to a system for the thermally controlled processing of biological material in a liquid sample in a multiwell plate using magnetic particles. Also disclosed is a corresponding method for the thermally controlled processing of biological material in a liquid sample.
    Type: Application
    Filed: January 25, 2019
    Publication date: August 8, 2019
    Inventors: Roland Bernet, Claudio Cherubini, Pius Hermann, Emad Sarofim
  • Patent number: 10359442
    Abstract: A sample container carrier for transporting sample containers, for example test tubes and/or vials, in a laboratory automation system is presented. The sample container carrier comprises a body having a hollow center with a central axis. The hollow center accommodates a lower end of a sample container. The sample container carrier also comprises three resiliently deformable and/or displaceable first retaining elements mounted to the body. The first retaining elements, distributed about the central axis, clamp a sample container inserted in the hollow center. The sample container carrier also comprises three resiliently deformable and/or displaceable second retaining elements mounted to the body. The second retaining elements, distributed about the central axis, clamp the sample container inserted in the hollow center underneath the three first retaining elements. The second retaining elements are arranged at least partly inside the hollow center.
    Type: Grant
    Filed: February 16, 2017
    Date of Patent: July 23, 2019
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Marcel Kaeppeli, Pius Hermann
  • Publication number: 20190086433
    Abstract: A laboratory sample distribution system comprising a transport plane in which the transport plane is covered by an electrically conductive material is presented. A laboratory automation system comprising such a laboratory sample distribution system is also presented.
    Type: Application
    Filed: November 19, 2018
    Publication date: March 21, 2019
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Pius Hermann, Jonathan Baer
  • Publication number: 20180348245
    Abstract: A transport device unit for a transport device assembled using a plurality of transport device units is presented. The transport device unit comprises a base plate module with a base plate for fixing the transport device unit to a support frame, an actuator module with a plurality of electro-magnetic actuators, where the actuator module is supported by the base plate module, and a driving surface module with a driving surface element, where the driving surface element is arranged above the actuator module covering the actuators and configured to carry sample container carriers. A transport device, a system for at least partially disassembling the transport device, and a laboratory sample distribution system comprising a transport device are also presented. In addition, a laboratory automation system comprising a laboratory sample distribution system is also presented.
    Type: Application
    Filed: August 2, 2018
    Publication date: December 6, 2018
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Hans Schneider, Eugen Lusser, Marcel Kaeppeli, Tobias Huber, Pius Hermann, Matthias Edelmann
  • Publication number: 20180340952
    Abstract: A transport device for a laboratory sample distribution system is presented. The transport device comprises a plurality of actuator modules. Each actuator module comprises a plurality of electro-magnetic actuators. A plurality of base plate modules arranged in a pattern is provided. The base plate modules are coupled to each other and aligned by support elements. The number of base plate modules at least equals the number of actuator modules and each base plate module is configured to support one of the plurality of actuator modules. A laboratory sample distribution system and to a laboratory automation system comprising a laboratory sample distribution system are also presented.
    Type: Application
    Filed: August 2, 2018
    Publication date: November 29, 2018
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Marcel Kaeppeli, Tobias Huber, Pius Hermann, Matthias Edelmann
  • Publication number: 20180340951
    Abstract: A transport device for a laboratory sample distribution system is presented. The transport device comprises a plurality of electro-magnetic actuators and a driving surface arranged above the actuators, in which the driving surface is configured to carry sample container carriers. The driving surface is tiled and comprises a plurality of driving surface modules with driving surface elements. Support elements arranged in a grid pattern are provided. Each driving surface module is detachably mounted to a subset of the support elements. A laboratory sample distribution system and to a laboratory automation system comprising a laboratory sample distribution system are also presented.
    Type: Application
    Filed: August 2, 2018
    Publication date: November 29, 2018
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Marcel Kaeppeli, Tobias Huber, Pius Hermann, Matthias Edelmann
  • Publication number: 20170248624
    Abstract: A sample container carrier for transporting sample containers, for example test tubes and/or vials, in a laboratory automation system is presented. The sample container carrier comprises a body having a hollow center with a central axis (A). The hollow center is adapted for receiving a lower end of a sample container. The sample container carrier also comprises at least three resiliently deformable and/or displaceable upper retaining elements. The upper retaining elements are distributed about the central axis (A) and adapted to clamp a sample container inserted in the hollow center of the body. The upper retaining elements are made of plastic. A method for manufacturing a sample container carrier is also presented. At least the upper retaining elements are formed by injection molding. A laboratory sample distribution system having a number of sample container carriers and a laboratory automation system comprising a laboratory sample distribution system are also presented.
    Type: Application
    Filed: February 16, 2017
    Publication date: August 31, 2017
    Inventors: Marcel Kaeppeli, Pius Hermann
  • Publication number: 20170248623
    Abstract: A sample container carrier for transporting sample containers, for example test tubes and/or vials, in a laboratory automation system is presented. The sample container carrier comprises a body having a hollow center with a central axis. The hollow center accommodates a lower end of a sample container. The sample container carrier also comprises three resiliently deformable and/or displaceable first retaining elements mounted to the body. The first retaining elements, distributed about the central axis, clamp a sample container inserted in the hollow center. The sample container carrier also comprises three resiliently deformable and/or displaceable second retaining elements mounted to the body. The second retaining elements, distributed about the central axis, clamp the sample container inserted in the hollow center underneath the three first retaining elements. The second retaining elements are arranged at least partly inside the hollow center.
    Type: Application
    Filed: February 16, 2017
    Publication date: August 31, 2017
    Inventors: Marcel Kaeppeli, Pius Hermann