Patents by Inventor Piyush D. Fadadu

Piyush D. Fadadu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process of making regadenoson and novel polymorphs thereof
    Patent number: 11034714
    Abstract: Novel processes for making the N-pyrrazole substituted 2-adenosine derivative regadenoson and a novel polymorph thereof. The novel polymorph of regadenoson designated form H and drug substances and pharmaceutical compositions including the novel polymorph H are disclosed.
    Type: Grant
    Filed: August 28, 2019
    Date of Patent: June 15, 2021
    Inventors: Ravishanker Kovi, Jayaraman Kannapan, Piyush D. Fadadu, Ashish Naik
  • PROCESS OF MAKING REGADENOSON AND NOVEL POLYMORPHS THEREOF
    Publication number: 20200017539
    Abstract: Novel processes for making the N-pyrrazole substituted 2-adenosine derivative regadenoson and a novel polymorph thereof. The novel polymorph of regadenoson designated form H and drug substances and pharmaceutical compositions including the novel polymorph H are disclosed.
    Type: Application
    Filed: August 28, 2019
    Publication date: January 16, 2020
    Inventors: Ravishanker Kovi, Jayaraman Kannapan, Piyush D. Fadadu, Ashish Naik
  • Polymorph of regadenoson and process for preparation thereof
    Patent number: 10392417
    Abstract: Processes are provided for the preparation of a stable polymorphic form C of regadenoson, the process involving steps of a) obtaining a solution of regadenoson in benzyl alcohol solvent, b) maintaining the reaction mixture of step a) to about 10° C. to about 90° C., and c) isolating the stable polymorphic form C of regadenoson. Polymorphic form C may be characterized by an x-ray powder diffraction pattern with peaks at about 6.1, 10.2, 10.6, 19.0 and 25.4.±0.2 degrees 2-theta.
    Type: Grant
    Filed: October 30, 2017
    Date of Patent: August 27, 2019
    Assignee: Apicore US LLC
    Inventors: Ravishanker Kovi, Jayaraman Kannapan, Ananda Babu Thirunavakarasu, Piyush D. Fadadu, Piyush B. Thumar
  • NOVEL POLYMORPH OF REGADENOSON AND PROCESS FOR PREPARATION THEREOF
    Publication number: 20180127452
    Abstract: Processes are provided for the preparation of a stable polymorphic form C of regadenoson, the process involving steps of a) obtaining a solution of regadenoson in benzyl alcohol solvent, b) maintaining the reaction mixture of step a) to about 10° C. to about 90° C., and c) isolating the stable polymorphic form C of regadenoson. Polymorphic form C may be characterized by an x-ray powder diffraction pattern with peaks at about 6.1, 10.2, 10.6, 19.0 and 25.4.±0.2 degrees 2-theta.
    Type: Application
    Filed: October 30, 2017
    Publication date: May 10, 2018
    Applicant: Apicore US LLC
    Inventors: Ravishanker Kovi, Jayaraman Kannapan, Ananda Babu Thirunavakarasu, Piyush D. Fadadu, Piyush B. Thumar