Patents by Inventor Po-Liang Chen

Po-Liang Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170189419
    Abstract: The present invention provides a pharmaceutical composition for treating prostate cancer in a subject in need thereof, which comprises a first agent comprising at least a Anctin K (AnK); and a second agent comprising at least an Antroquinonol B (AnQB); as well as each of them can be obtained from the extractions of a fruiting body or a mycelium of Antrodia camphorata wherein the first agent and the second agent shows synergistic effect for use in the treatment of prostate cancer or to prevent or to reduce the risk of a prostate cancer metastasizing, compared to administration of the first agent or the second agent alone.
    Type: Application
    Filed: December 30, 2015
    Publication date: July 6, 2017
    Inventor: Po-Liang Chen
  • Publication number: 20170189417
    Abstract: The present invention provides a pharmaceutical composition for treating colorectal cancer in a subject in need thereof, which comprises a first agent comprising at least a Zhankuic acid D (ZhAD); and a second agent comprising at least an Antroquinonol B (AnQB); as well as each of them can be obtained from the extractions of a fruiting body or a mycelium of Antrodia camphorata wherein the first agent and the second agent shows synergistic effect for use in the treatment of colorectal cancer or to prevent or to reduce the risk of a colorectal cancer metastasizing, compared to administration of the first agent or the second agent alone.
    Type: Application
    Filed: December 30, 2015
    Publication date: July 6, 2017
    Inventor: PO-LIANG CHEN
  • Publication number: 20170189418
    Abstract: The present invention provides a pharmaceutical composition for treating lung cancer in a subject in need thereof, which comprises a first agent comprising at least a dehydroeburicoic acid (DeEA); and a second agent comprising at least an Anctin K(AnK); as well as each of them can be obtained from the extractions of a fruiting body or a mycelium of Antrodia camphorata wherein the first agent and the second agent shows synergistic effect for use in the treatment of lung cancer or to prevent or to reduce the risk of a lung cancer metastasizing, compared to administration of the first agent or the second agent alone.
    Type: Application
    Filed: December 30, 2015
    Publication date: July 6, 2017
    Inventor: Po-Liang Chen
  • Publication number: 20170189416
    Abstract: The present invention provides a pharmaceutical composition for treating breast cancer in a subject in need thereof, which comprises a first agent comprising at least a dehydroeburicoic acid (DeEA); and a second agent comprising at least an Antroquinonol B (AnQB); as well as each of them can be obtained from the extractions of a fruiting body or a mycelium of Antrodia camphorata wherein the first agent and the second agent shows synergistic effect for use in the treatment of breast cancer or to prevent or to reduce the risk of a breast cancer metastasizing, compared to administration of the first agent or the second agent alone.
    Type: Application
    Filed: December 30, 2015
    Publication date: July 6, 2017
    Inventor: PO-LIANG CHEN
  • Publication number: 20170112856
    Abstract: A pharmaceutical composition for treating cancer in an individual, comprising at least a pharmaceutically effective amount of a novel target HCC reversal signal substance, and a pharmaceutically acceptable ingredient comprising a vehicle, a carrier, a diluent or an excipient; and the novel target HCC reversal signal substance is a mixture that consisting of antroquinonol (AQL), antrocinnamonin A (ACA), antroquinonol B (AQB), antroquinonol D (AQD), dehydroeburicoic acid (DEA), dehydrosulphurenic acid (DSA), zhankuic acid A (ZAA), zhankuic acid C (ZAC), antcin K (ANK), antcin C (ANC); in which the ratio among each component of the pharmaceutical composition may be adjustable depending on the type of cancer; wherein the pharmaceutical composition is used for cancer suppression activity of which comprises at least one selected from human breast cancer cell line MCF-7, human hepatoma cell line HepG2, human colorectal cancer cell line HCT116, human colon cancer cell line RKO, human tissue leukocyte cell line U937,
    Type: Application
    Filed: January 3, 2017
    Publication date: April 27, 2017
    Inventor: PO-LIANG CHEN
  • Publication number: 20170042912
    Abstract: A pharmaceutical composition for treating cancer in an individual, comprising at least a pharmaceutically effective amount of a novel target HCC reversal signal substance, and a pharmaceutically acceptable ingredient comprising a vehicle, a carrier, a diluent or an excipient; in which the ratio among each component of the pharmaceutical composition may be adjustable depending on the type of cancer; wherein the novel target HCC reversal signal substance comprises at least one selected from the group consisting of antroquinonol (AQL), antrocinnamonin A (ACA), antroquinonol B (AQB), antroquinonol D (AQD), dehydroeburicoic acid (DEA), dehydrosulphurenic acid (DSA), zhankuic acid A (ZAA), zhankuic acid C (ZAC), antcin K (ANK), antcin C (ANC), and a mixture thereof.
    Type: Application
    Filed: September 14, 2015
    Publication date: February 16, 2017
    Inventor: PO-LIANG CHEN
  • Publication number: 20170036986
    Abstract: A method for extracting active principles from fruiting bodies of Antrodia camphorata comprises the steps of: extracting fruiting bodies of Antrodia camphorata with hot water to obtain extracts HW, and thus extraction residues (residues HW) are remained; extracting the residues HW by a fractional distillation to obtain extracts FD, and thus extraction residues (residues FD) are remained; extracting the residues FD by immersing with a low polar solvent to obtain extracts LPS, and thus extraction residues (residues LPS) are remained; extracting the residues LPS through a cryo-condensation process to obtain extracts IEW, and thus extraction residues (residues IEW) are remained; extracting the residues IEW through a SCF by using CO2 as a solvent to obtain extracts SCF, and thus extraction residues (residues SCF) are remained; and forming a mixture by mixing one or more extracts selected from the group consisting of extracts HW, FD, LPS, IEW, and SCF.
    Type: Application
    Filed: August 6, 2015
    Publication date: February 9, 2017
    Inventor: Po-Liang Chen
  • Publication number: 20160375072
    Abstract: Carrier structure imitating biological interstitial system is provided, comprising a carrier and a plurality of ligands. The carrier encloses particles of Taiwanofungus camphoratus. The carrier comprises first and second liposome shells. A first space is defined inside the first liposome shell. The second liposome shell encloses the first liposome shell. An external radius of the first liposome shell is smaller than an internal radius of the second liposome shell, a second space is defined between an inside of the second liposome shell and an outside of the first liposome shell. The ligands follow at least one orbit surrounding the carrier. When approaching a specific cancer cell, the ligands move towards receptors thereof and combine therewith, so that the carrier compresses; when the carrier disintegrates due to compression, the particles of Taiwanofungus camphoratus are released and then scatter on the receptors to destroy the cancer cell.
    Type: Application
    Filed: August 11, 2015
    Publication date: December 29, 2016
    Inventor: PO-LIANG CHEN
  • Patent number: 8305583
    Abstract: A sensing system comprises a light source, an optical fiber, a plurality of noble metal nano-particles, a micro-fluidic module and a photo detector. The optical fiber couples an incident light. The plurality of noble metal nano-particles are disposed on a surface of the optical fiber to form a noble metal nano-particle submonolayer, the noble metal nano-particles are substantially separated from each adjacent noble metal nano-particles such that the conductivity of the noble metal nano-particle submonolayer is smaller than that of a metal film. The micro-fluidic module accommodates the optical fiber and a sample, and the sample is driven to contact with the noble metal nano-particles. The photo detector detects an emergent light from the optical fiber. When the incident light interacts with the noble metal nano-particles, a signal derived from localized surface plasmon resonance in form of attenuated light or elastic scattered light is outputted through the photo detector.
    Type: Grant
    Filed: December 24, 2009
    Date of Patent: November 6, 2012
    Assignee: National Chung Cheng University
    Inventors: Lai-Kwan Chau, Wen-Hsin Hsieh, Wei-Ting Hsu, Po-Liang Chen
  • Publication number: 20100128275
    Abstract: A sensing system comprises a light source, an optical fiber, a plurality of noble metal nano-particles, a micro-fluidic module and a photo detector. The optical fiber couples an incident light. The plurality of noble metal nano-particles are disposed on a surface of the optical fiber to form a noble metal nano-particle submonolayer, the noble metal nano-particles are substantially separated from each adjacent noble metal nano-particles such that the conductivity of the noble metal nano-particle submonolayer is smaller than that of a metal film. The micro-fluidic module accommodates the optical fiber and a sample, and the sample is driven to contact with the noble metal nano-particles. The photo detector detects an emergent light from the optical fiber. When the incident light interacts with the noble metal nano-particles, a signal derived from localized surface plasmon resonance in form of attenuated light or elastic scattered light is outputted through the photo detector.
    Type: Application
    Filed: December 24, 2009
    Publication date: May 27, 2010
    Applicant: NATIONAL CHUNG CHENG UNIVERSITY
    Inventors: Lai-Kwan Chau, Wen-Hsin Hsieh, Wei-Ting Hsu, Po-Liang Chen
  • Publication number: 20080019876
    Abstract: This invention discloses a sensing apparatus with noble metal and sensing system and its method. The sensing apparatus with noble metal comprises a planar waveguide, a noble metal nano-particle layer, and a cover. The planar waveguide has a top plane. The noble metal nano-particle layer is uniformly distributed on the top plane of the planar waveguide. The cover has a notch, and is covered on the top plane of the planar waveguide to form a space between the notch and the top plane. Accordingly, a plurality of incident lights are led into the sensing apparatus with noble metal nano-particle to detect a testing substance contained in the aforesaid space.
    Type: Application
    Filed: December 19, 2006
    Publication date: January 24, 2008
    Inventors: Lai-Kwan Chau, Wen-Hsin Hsieh, Po-Liang Chen, Kaua-Ciih Chiu, Wei-Ting Hsu
  • Publication number: 20070257778
    Abstract: A projection apparatus includes a first wireless unit receiving signals from a first external wireless remote controller, a second external wireless unit receiving signals from a second wireless remote controller, a signal-processing unit respectively coupled with the first wireless unit and the second wireless unit to receive signals, a CPU coupled with the signal-processing unit to receive processed signals from the signal-processing unit, and a projecting unit coupled with the CPU to perform a projecting function in accordance with the signal transmitted from the CPU.
    Type: Application
    Filed: January 11, 2007
    Publication date: November 8, 2007
    Inventors: Chih-Neng Tseng, Chih-Nan Wu, Po-Liang Chen
  • Publication number: 20070109544
    Abstract: A surface plasmon resonance sensing system comprised of an incidence illuminant, a modified optical fiber, a layer of gold nanoparticles, a micro-fluidic module, and an illuminant detector; the modified optical fiber related to an optical fiber stripped off a portion of its protection layer and a cladding layer; the layer of noble metal nanoparticles covering over the modified optical fiber; the micro-fluidic module related to a micro-fluidic chip for containing the modified optical fiber and a sample; and the illuminant detector operating to detect the light emitted from the modified optical fiber.
    Type: Application
    Filed: November 10, 2006
    Publication date: May 17, 2007
    Inventors: Lai-Kwan Chau, Wen-Hsin Hsieh, Wei-Ting Hsu, Po-Liang Chen