Patents by Inventor Polina Lapido

Polina Lapido has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12157729
    Abstract: The present disclosure encompasses solid state forms of Belumosudil, in embodiments crystalline polymorphs of Belumosudil or salts thereof, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: December 22, 2023
    Date of Patent: December 3, 2024
    Assignee: TEVA PHARMACEUTICALS INTERNATIONAL GMBH
    Inventors: Polina Lapido, Inbal Shumacher, Ofir Shaul
  • Publication number: 20240208889
    Abstract: The present disclosure encompasses solid state forms of Tapinarof, in embodiments crystalline polymorphs or co-crystals of Tapinarof, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: May 19, 2021
    Publication date: June 27, 2024
    Applicant: TEVA PHARMACEUTICALS INTERNATIONAL GMBH
    Inventors: Polina Lapido, Doron Rudik
  • Publication number: 20240124425
    Abstract: The present disclosure encompasses solid state forms of Belumosudil, in embodiments crystalline polymorphs of Belumosudil or salts thereof, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: December 22, 2023
    Publication date: April 18, 2024
    Inventors: Polina Lapido, Inbal Shumacher, Ofir Shaul
  • Patent number: 11932627
    Abstract: The present disclosure encompasses solid state forms of Belumosudil, in embodiments crystalline polymorphs of Belumosudil or salts thereof, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: August 22, 2023
    Date of Patent: March 19, 2024
    Assignee: TEVA PHARMACEUTICALS INTERNATIONAL GMBH
    Inventors: Polina Lapido, Inbal Shumacher, Ofir Shaul
  • Patent number: 11891380
    Abstract: The present disclosure encompasses solid state forms of Belumosudil, in embodiments crystalline polymorphs of Belumosudil or salts thereof, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: August 22, 2023
    Date of Patent: February 6, 2024
    Assignee: TEVA PHARMACEUTICALS INTERNATIONAL GMBH
    Inventors: Polina Lapido, Inbal Shumacher, Ofir Shaul
  • Publication number: 20230391755
    Abstract: The present disclosure encompasses solid state forms of Belumosudil, in embodiments crystalline polymorphs of Belumosudil or salts thereof, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: August 22, 2023
    Publication date: December 7, 2023
    Inventors: Polina Lapido, Inbal Shumacher, Ofir Shaul
  • Publication number: 20230364099
    Abstract: The present disclosure encompasses solid state forms of Resmetirom, in embodiments crystalline polymorphs of Resmetirom, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: October 19, 2021
    Publication date: November 16, 2023
    Inventors: Polina Lapido, Jenny Goldshtein, Vitaly Krimer, Doron Rudik
  • Publication number: 20230339962
    Abstract: Solid state forms of SEP-363856 HBr, SEP-363856 Fumarate, SEP-363856 R-camsylate and SEP-363856 S-camsylate and processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: September 15, 2021
    Publication date: October 26, 2023
    Inventors: Polina Lapido, Limor Adani
  • Patent number: 11773083
    Abstract: The present disclosure encompasses solid state forms of Belumosudil, in embodiments crystalline polymorphs of Belumosudil or salts thereof, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: December 6, 2022
    Date of Patent: October 3, 2023
    Assignee: TEVA PHARMACEUTICALS INTERNATIONAL GMBH
    Inventors: Polina Lapido, Inbal Shumacher, Ofir Shaul
  • Publication number: 20230117059
    Abstract: The present disclosure encompasses solid state forms of Belumosudil, in embodiments crystalline polymorphs of Belumosudil or salts thereof, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: December 6, 2022
    Publication date: April 20, 2023
    Inventors: Polina Lapido, Inbal Shumacher, Ofir Shaul
  • Publication number: 20230098234
    Abstract: Solid state forms of Mitapivat, Mitapivat hemisulfate, Mitapivat HCl, Mitapivat phosphate, Mitapivat hemisulfate:ascorbic acid and Mitapivat hemisulfate:adipic acid, processes for preparation thereof, pharmaceutical compositions there-of, and uses thereof are disclosed.
    Type: Application
    Filed: January 28, 2021
    Publication date: March 30, 2023
    Inventors: Polina Lapido, Doron Rudik, Ofir Shaul
  • Publication number: 20230058102
    Abstract: The present disclosure encompasses a novel solid state form of Blarcamesine and salts thereof, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: February 3, 2021
    Publication date: February 23, 2023
    Inventors: Polina Lapido, Jenny Goldshtein
  • Publication number: 20220220149
    Abstract: The present disclosure encompasses solid state forms of SAGE-217, in embodiments SAGE-217:Oxalic acid Co-crystal, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: May 14, 2020
    Publication date: July 14, 2022
    Inventors: Polina Lapido, Ofir Shaul, Firas Masri
  • Publication number: 20210179586
    Abstract: The present disclosure relates to Branaplam solid state forms, Branaplam salts and solid states thereof, processes for preparation thereof, pharmaceutical compositions and methods of use thereof.
    Type: Application
    Filed: September 5, 2019
    Publication date: June 17, 2021
    Inventors: Luna Ben-Sahel Katsav, Doron Rudik, Firas Masri, Motti Erlich, Polina Lapido, Ofir Shaul, Sigalit Patael
  • Patent number: 10335745
    Abstract: The present invention provides a semipermeable membrane having enhanced alkaline stability and a method of forming a semipermeable membrane having enhanced alkaline stability, comprising steps of: providing an ultrafiltration (UF) base membrane, immersing said UF membrane in a solution comprising at least one substance selected from the group consisting of a polymer preferably polyethylenimine (PEI), a condensate solution and a mixture thereof, thereby forming reactive moieties upon said UF membrane, and forming at least one first layer upon at least portion of said UF base support membrane by immersing said UF base support membrane of step (b) in a solution comprising at least one ingredient selected from the group consisting of polymer preferably polyethylenimine (PEI), condensate solution and a mixture thereof thereby forming a cross-linked skin on the surface of said base membrane.
    Type: Grant
    Filed: September 18, 2014
    Date of Patent: July 2, 2019
    Assignee: AMS TECHNOLOGIES INT. (2012) LTD
    Inventors: Polina Lapido, Vera Ginzburg, Hagit Shalev, Boris Ginzburg
  • Publication number: 20180273499
    Abstract: The present disclosure relates to new salts of Vortioxetine, including butyrate, iso-butyrate, benzoate and propionate, solid state forms of the Vortioxetine salts, processes for the preparation thereof, pharmaceutical formulations/compositions thereof, and methods of use thereof.
    Type: Application
    Filed: March 19, 2018
    Publication date: September 27, 2018
    Applicant: Teva Pharmaceuticals International GmbH
    Inventors: Sharona SHACHANTOV, Doron RUDIK, Ariel MITTELMAN, Rotem SELLA-EREZ, Yuval COHEN, Jonathan ENAV, Vera KESELMAN, Gustavo FRENKEL, Moshe BAR, Polina LAPIDO
  • Patent number: 9943811
    Abstract: Solvent and acid stable ultrafiltration and nanofiltration membranes including a non-cross-linked base polymer having reactive pendant moieties, the base polymer being modified by forming a cross-linked skin onto a surface thereof, the skin being formed by a cross-linking reaction of reactive pendant moieties on the surface with an oligomer or another polymer as well as methods of manufacture and use thereof, including, inter alia separating metal ions from liquid process streams.
    Type: Grant
    Filed: November 2, 2015
    Date of Patent: April 17, 2018
    Assignee: AMS TECHNOLOGIES IN. (2012) LTD
    Inventors: Mordechai Perry, Vera Ginzburg, Boris Ginzburg, Polina Lapido
  • Publication number: 20160207010
    Abstract: The present invention provides a semipermeable membrane having enhanced alkaline stability and a method of forming a semipermeable membrane having enhanced alkaline stability, comprising steps of: providing an ultrafiltration (UF) base membrane, immersing said UF membrane in a solution comprising at least one substance selected from the group consisting of a polymer preferably polyethylenimine (PEI), a condensate solution and a mixture thereof, thereby forming reactive moieties upon said UF membrane, and forming at least one first layer upon at least portion of said UF base support membrane by immersing said UF base support membrane of step (b) in a solution comprising at least one ingredient selected from the group consisting of polymer preferably polyethylenimine (PEI), condensate solution and a mixture thereof thereby forming a cross-linked skin on the surface of said base membrane.
    Type: Application
    Filed: September 18, 2014
    Publication date: July 21, 2016
    Applicant: AMS TECHNOLOGIES INT. (2012) LTD
    Inventors: Polina LAPIDO, Vera GINZBURG, Hagit SHALEV, Boris GINZBURG
  • Publication number: 20160051944
    Abstract: Solvent and acid stable ultrafiltration and nanofiltration membranes including a non-cross-linked base polymer having reactive pendant moieties, the base polymer being modified by forming a cross-linked skin onto a surface thereof, the skin being formed by a cross-linking reaction of reactive pendant moieties on the surface with an oligomer or another polymer as well as methods of manufacture and use thereof, including, inter alia separating metal ions from liquid process streams.
    Type: Application
    Filed: November 2, 2015
    Publication date: February 25, 2016
    Applicant: AMS TECHNOLOGIES INT. (2012) LTD
    Inventors: Mordechai PERRY, Vera GINZBURG, Boris GINZBURG, Polina LAPIDO
  • Patent number: 9205383
    Abstract: Solvent and acid stable ultrafiltration and nanofiltration membranes including a non-cross-linked base polymer having reactive pendant moieties, the base polymer being modified by forming a cross-linked skin onto a surface thereof, the skin being formed by a cross-linking reaction of reactive pendant moieties on the surface with an oligomer or another polymer as well as methods of manufacture and use thereof, including, inter alia separating metal ions from liquid process streams.
    Type: Grant
    Filed: January 13, 2010
    Date of Patent: December 8, 2015
    Assignee: AMS TECHNOLOGIES INT. (2012) LTD
    Inventors: Mordechai Perry, Vera Ginzburg, Boris Ginzburg, Polina Lapido