Patents by Inventor Polly A. Wong

Polly A. Wong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Expression of pace in host cells and methods of use thereof
    Patent number: 5986079
    Abstract: Compositions and methods are provided for endopeptidase production and for enhanced efficiencies of processing heterologous precursor polypeptides to mature polypeptides, including proteins requiring gamma-carboxylation for biological activity. These compositions and methods utilize recombinant PACE, a mammalian endopeptidase that is specific for dibasic amino acid sites.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 16, 1999
    Assignees: Genetics Institute, Inc., Chiron Corporation
    Inventors: Philip J. Barr, Anthony J. Brake, Randal J. Kaufman, Patricia Tekamp-Olson, Louise Wasley, Polly A. Wong
  • Expression of pace in host cells and methods of use thereof
    Patent number: 5965425
    Abstract: Compositions and methods are provided for endopeptidase production and for enhanced efficiencies of processing heterologous precursor polypeptides to mature polypeptides, including proteins requiring gamma-carboxylation for biological activity. These compositions and methods utilize recombinant PACE, a mammalian endopeptidase that is specific for dibasic amino acid sites.
    Type: Grant
    Filed: November 8, 1996
    Date of Patent: October 12, 1999
    Assignees: Genetics Institute, Inc., Chiron Corporation
    Inventors: Philip J. Barr, Anthony J. Brake, Randal J. Kaufman, Patricia Tekamp-Olson, Louise Wasley, Polly A. Wong
  • Expression of PACE in host cells and methods of use thereof
    Patent number: 5460950
    Abstract: Compositions and methods are provided for endopeptidase production and for enhanced efficiencies of processing heterologous precursor polypeptides to mature polypeptides, including proteins requiring gamma-carboxylation for biological activity. These compositions and methods utilize recombinant PACE, a mammalian endopeptidase that is specific for dibasic amino acid sites.
    Type: Grant
    Filed: May 20, 1992
    Date of Patent: October 24, 1995
    Assignees: Genetics Institute, Inc., Chiron Corporation
    Inventors: Philip J. Barr, Anthony J. Brake, Randal J. Kaufman, Louise Wasley, Patricia Tekamp-Olson, Polly A. Wong