Patents by Inventor Polly Hofmann

Polly Hofmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of PKC-activating compounds as cardioprotectants and as apoptosis-inducing anti-tumor agents
    Patent number: 7541342
    Abstract: Compounds for the inducing apoptosis in cancer cells are described. The described compounds induce the translocation of protein kinase C-? to the mitochondria and the phosphorylation of mitochondrial phospholipid scramblase 3. The compounds also provide cardioprotection through the translocation and activation of protein kinase C-? in cardiomyocytes, thereby inhibiting apoptosis in carciomyocytes.
    Type: Grant
    Filed: March 6, 2006
    Date of Patent: June 2, 2009
    Assignee: University of Tennessee Research Foundation
    Inventors: Leonard Lothstein, Mervyn Israel, Trevor Sweatman, Polly A. Hofmann
  • Use of PKC-activating compounds as cardioprotectants and as apoptosis-inducing anti-tumor agents
    Publication number: 20060199775
    Abstract: Compounds for the inducing apoptosis in cancer cells are described. The described compounds induce the translocation of protein kinase C-? to the mitochondria and the phosphorylation of mitochondrial phospholipid scramblase 3. The compounds also provide cardioprotection through the translocation and activation of protein kinase C-? in cardiomyocytes, thereby inhibiting apoptosis in carciomyocytes.
    Type: Application
    Filed: March 6, 2006
    Publication date: September 7, 2006
    Inventors: Leonard Lothstein, Mervyn Israel, Trevor Sweatman, Polly Hofmann