Patents by Inventor Polly Roy

Polly Roy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reoviridae vaccine
    Patent number: 10688176
    Abstract: The invention relates to an isolated African horse sickness virus (AHSV) ssRNA comprising a plurality of mutations; a complementary cell for replication of a vaccinal viral strain from said ssRNA; a vaccinal viral strain derived from said ssRNA; use of said vaccinal viral strain and/or isolated ssRNA in the vaccination of an animal against an infection by AHSV; a method of vaccination comprising same; and a pharmaceutical composition comprising said vaccinal viral strain and/or said isolated ssRNA.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: June 23, 2020
    Assignee: London School of Hygiene & Tropical Medicine
    Inventor: Polly Roy
  • REOVIRIDAE VACCINE
    Publication number: 20190060442
    Abstract: The invention relates to an isolated African horse sickness virus (AHSV) ssRNA comprising a plurality of mutations; a complementary cell for replication of a vaccinal viral strain from said ssRNA; a vaccinal viral strain derived from said ssRNA; use of said vaccinal viral strain and/or isolated ssRNA in the vaccination of an animal against an infection by AHSV; a method of vaccination comprising same; and a pharmaceutical composition comprising said vaccinal viral strain and/or said isolated ssRNA.
    Type: Application
    Filed: April 10, 2017
    Publication date: February 28, 2019
    Applicant: London School of Hygiene & Tropical Medicine
    Inventor: Polly ROY
  • PHARMACEUTICAL COMPOSITION FOR TREATING A VIRAL INFECTION
    Publication number: 20170304350
    Abstract: The invention concerns a pharmaceutical composition for treating a viral infection caused by a member of the Reoviridae family; a method of treatment involving the use of same and use of the anti-viral to treat said viral infection. The agent has use in both humans and animals.
    Type: Application
    Filed: October 7, 2015
    Publication date: October 26, 2017
    Applicant: London School of Hygiene & Tropical Medicine
    Inventor: Polly Roy
  • Vectors
    Patent number: 9777260
    Abstract: The present invention relates to a transfer vector for inserting a gene into a genetic locus of a baculovirus sequence. The transfer vector comprises an expression cassette comprising a eukaryotic promoter operably linked to the gene and a bipartite selection cassette. The present invention also relates to methods of using the transfer vector and derived bacmids and baculoviruses.
    Type: Grant
    Filed: November 30, 2015
    Date of Patent: October 3, 2017
    Assignee: London School of Hygiene and Tropical Medicine
    Inventors: Polly Roy, Robert James Noad
  • Method for producing vaccinal viral strain of a virus of the family
    Patent number: 9457076
    Abstract: The invention relates to a method for producing a modified viral strain of a virus which is a member of the Reoviridae family and, in particular, relates to vaccinal viral strains of the Orbivirus genus.
    Type: Grant
    Filed: January 28, 2014
    Date of Patent: October 4, 2016
    Assignee: London School of Hygiene and Tropical Medicine
    Inventors: Polly Roy, Mark Boyce
  • VECTORS
    Publication number: 20160090575
    Abstract: The present invention relates to a transfer vector for inserting a gene into a genetic locus of a baculovirus sequence. The transfer vector comprises an expression cassette comprising a eukaryotic promoter operably linked to the gene and a bipartite selection cassette. The present invention also relates to methods of using the transfer vector and derived bacmids and baculoviruses.
    Type: Application
    Filed: November 30, 2015
    Publication date: March 31, 2016
    Applicant: London School of Hygiene and Tropical Medicine
    Inventors: Polly Roy, Robert James Noad
  • Vectors
    Patent number: 9212374
    Abstract: The present invention relates to a transfer vector for inserting a gene into a genetic locus of a baculovirus sequence. The transfer vector comprises an expression cassette comprising a eukaryotic promoter operably linked to the gene and a bipartite selection cassette. The present invention also relates to methods of using the transfer vector and derived bacmids and baculoviruses.
    Type: Grant
    Filed: November 11, 2009
    Date of Patent: December 15, 2015
    Assignee: London School of Hygiene and Tropical Medicine
    Inventors: Polly Roy, Robert James Noad
  • METHOD FOR PRODUCING VACCINAL VIRAL STRAIN OF A VIRUS OF THE REOVIRIDAE FAMILY
    Publication number: 20140134209
    Abstract: The invention relates to a method for producing a modified viral strain of a virus which is a member of the Reoviridae family and, in particular, relates to vaccinal viral strains of the Orbivirus genus.
    Type: Application
    Filed: January 28, 2014
    Publication date: May 15, 2014
    Applicant: London School of Hygiene & Tropical Medicine
    Inventors: Polly Roy, Mark Boyce
  • Method for producing vaccinal viral strain of a virus of the reoviridae family
    Patent number: 8673315
    Abstract: The invention relates to a method for producing a modified viral strain of a virus which is a member of the Reoviridae family and, in particular, relates to vaccinal viral strains of the Orbivirus genus.
    Type: Grant
    Filed: November 26, 2008
    Date of Patent: March 18, 2014
    Assignee: London School of Hygiene & Tropical Medicine
    Inventors: Polly Roy, Mark Boyce
  • VECTORS
    Publication number: 20110281261
    Abstract: The present invention relates to a transfer vector for inserting a gene into a genetic locus of a baculovirus sequence. The transfer vector comprises an expression cassette comprising a eukaryotic promoter operably linked to the gene and a bipartite selection cassette. The present invention also relates to methods of using the transfer vector and derived bacmids and baculoviruses.
    Type: Application
    Filed: November 11, 2009
    Publication date: November 17, 2011
    Inventors: Polly Roy, Robert James Noad
  • METHOD FOR PRODUCING VACCINAL VIRAL STRAIN OF A VIRUS OF THE REOVIRIDAE FAMILY
    Publication number: 20100322971
    Abstract: The invention relates to a method for producing a modified viral strain of a virus which is a member of the Reoviridae family and, in particular, relates to vaccinal viral strains of the Orbivirus genus.
    Type: Application
    Filed: November 26, 2008
    Publication date: December 23, 2010
    Inventors: Polly Roy, Mark Boyce
  • Use of bluetongue virus proteins as vaccine components
    Patent number: 5833995
    Abstract: A protective effect against bluetongue infection in susceptible mammals which is obtained by innoculating said mammals with a polypeptide comprising at least an antigenic portion of bluetongue virus structural protein VP2 in antigenic form produced by transforming a host with a recombinant expression vector having a DNA segment coding for said polypeptide.
    Type: Grant
    Filed: August 18, 1994
    Date of Patent: November 10, 1998
    Assignees: Oravax, Inc., Natural Environmental Research Council
    Inventors: Polly Roy, Timothy J. French
  • Oral immunization with multiple particulate antigen delivery system
    Patent number: 5690938
    Abstract: Method of inducing a mucosal and or/systemic immune response in a host, comprising the step of administering to the host an effective amount of a Bluetongue antigen in the form of virus like and/or virus core like particles. Vaccines are also provided.
    Type: Grant
    Filed: October 5, 1993
    Date of Patent: November 25, 1997
    Assignees: Oravax, Inc., Natural Environment Research Council
    Inventors: Thomas H. Ermak, Jacques Pappo, Farshad Guirakhoo, Richard D. Nichols, Jr., Thomas P. Monath, Polly Roy
  • Production of antigens by self-assembly of polypeptide components
    Patent number: 5686270
    Abstract: Antigens are produced by self-assembly of polypeptide components. The production of bluetongue virus antigens (BTV) in the form of assembled particles comprising separate polypeptide components, particularly proteins VP2, VP3, VP5 and VP7 is described.
    Type: Grant
    Filed: June 21, 1995
    Date of Patent: November 11, 1997
    Assignees: Oravax, Inc., Natural Environmental Research Council
    Inventors: Polly Roy, Timothy J. French
  • Multiple particulate antigen delivery system
    Patent number: 5667782
    Abstract: Antigens in particulate form are provided wherein chimeric antigens having foreign epitopes are presented on or within virus-like particles (VLPs) or virus core-like particles (CLPs). The VLPs and CLPs are immunogenic and are useful in producing vaccine formulations.
    Type: Grant
    Filed: June 30, 1995
    Date of Patent: September 16, 1997
    Assignee: Oxford University
    Inventor: Polly Roy