Patents by Inventor Polona Jurkovic

Polona Jurkovic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of a pharmaceutical composition comprising ezetimibe
    Patent number: 9089486
    Abstract: The present invention belongs to the field of pharmaceutical industry and relates to a process for preparing dosage forms containing ezetimibe, comprising the steps of: a) providing a composition comprising ezetimibe, b) sieving a composition comprising a composition of step (a), c) shear mixing of the composition after step (b), preferably the mixing of the composition is carried out by high shear mixing, d) formulation into a dosage form. The present invention also relates to dosage forms containing ezetimibe and ezetimibe and simvastatin, which have been prepared according to the process according to the invention.
    Type: Grant
    Filed: February 5, 2010
    Date of Patent: July 28, 2015
    Assignee: LEK PHARMACEUTICALS D.D.
    Inventors: Janez Kerc, Miha Homar, Polona Jurkovic
  • Self-microemulsifying drug delivery systems
    Patent number: 8592490
    Abstract: Self-microemulsifying drug delivery systems and microemulsions used to enhance the solubility of pharmaceutical ingredients comprising a polyoxyethylene sorbitan fatty acid ester emulsifier; a fatty acid ester co-emulsifier and an oil.
    Type: Grant
    Filed: December 14, 2007
    Date of Patent: November 26, 2013
    Assignee: LEK Pharmaceuticals D.D.
    Inventors: Igor Legen, Janez Kerc, Polona Jurkovic
  • PROCESS FOR THE PREPARATION OF A PHARMACEUTICAL COMPOSITION COMPRISING EZETIMIBE
    Publication number: 20120135976
    Abstract: The present invention belongs to the field of pharmaceutical industry and relates to a process for preparing dosage forms containing ezetimibe, comprising the steps of: a) providing a composition comprising ezetimibe, b) sieving a composition comprising a composition of step (a), c) shear mixing of the composition after step (b), preferably the mixing of the composition is carried out by high shear mixing, d) formulation into a dosage form. The present invention also relates to dosage forms containing ezetimibe and ezetimibe and simvastatin, which have been prepared according to the process according to the invention.
    Type: Application
    Filed: February 5, 2010
    Publication date: May 31, 2012
    Applicant: LEK PHARMACEUTICALS D.D.
    Inventors: Janez Kerc, Miha Homar, Polona Jurkovic
  • PREPARATION OF NANOPARTICLES BY USING A VIBRATING NOZZLE DEVICE
    Publication number: 20110068497
    Abstract: A method for preparing nanoparticles is provided, which comprises the steps of dissolving a polymer and, optionally, at least one additional ingredient, in an organic solvent, passing the solution through a vibrating nozzle and dropping the solution through the electrical field into an aqueous solution, which is stirred, such that nanoparticles are formed by the rapid diffusion of the solvent.
    Type: Application
    Filed: January 29, 2009
    Publication date: March 24, 2011
    Applicant: LEK PHARMACEUTICALS D.D.
    Inventors: Pegi Ahlin Grabnar, Alenka Zvonar, Julijana Kristl, Polona Jurkovic, Janez Kerc
  • CONTROLLED RELEASE TAMSULOSIN HYDROCHLORIDE TABLETS AND A PROCESS OF MAKING THEM
    Publication number: 20110033534
    Abstract: The present invention relates to a controlled release preparation of tamsulosin hydrochloride comprising hydroxypropylcellulose and polyethylene oxide, and the process for making such pharmaceutical composition.
    Type: Application
    Filed: September 25, 2008
    Publication date: February 10, 2011
    Applicant: LEK PHARMACEUTICALS D.D.
    Inventors: Janez Kerc, Miha Homar, Polona Jurkovic
  • SELF-MICROEMULSIFYING DRUG DELIVERY SYSTEMS
    Publication number: 20100331356
    Abstract: Self-microemulsifying drug delivery systems and microemulsions used to enhance the solubility of pharmaceutical ingredients comprising a polyoxyethylene sorbitan fatty acid ester emulsifier; a fatty acid ester co-emulsifier and an oil.
    Type: Application
    Filed: December 14, 2007
    Publication date: December 30, 2010
    Applicant: LEK Pharmaceuticals d.d.
    Inventors: Igor Legen, Janez Kerc, Polona Jurkovic