Patents by Inventor Pon Samuel
Pon Samuel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240041050Abstract: A method of introducing a molecule of interest into an insect or an insect cell includes interacting a cell-penetrating peptide with a molecule of interest to form a complex. The structure is then placed in contact with an insect or an insect cell and allowing uptake of the complex into the insect or insect cell. Alternatively, an RNA polynucleotide (mRNA, or an RNAi-mediating molecule) can be introduced in an insect or an insect cell by interacting a peptide with the polynucleotide of interest to form a complex, allowing uptake of the RNA complex into the insect or insect cell, and expressing the polynucleotide in the insect or an insect cell.Type: ApplicationFiled: December 8, 2021Publication date: February 8, 2024Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: COURTNEY ANNE DAVIS-VOGEL, EDWIN J. MENDEZ, JAYAKUMAR PON SAMUEL, KATHERINE A. THILGES
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Publication number: 20230191427Abstract: A microfluidic sorting device and method employing dielectrophoresis (DEP) induced field flow separations are described herein. The microfluidic sorting device has a microchannel and an array of electrodes disposed along the microchannel. The electrodes may be oriented at an angle relative to the microchannel. Non-mammalian samples such as plant samples flow in the microchannel and through the electrode array. Current is passed through the electrodes causing a DEP force to be exerted on the samples. This force may generate a torque that causes one type of sample to rotate and slide along the electrodes, thus separating the samples by type.Type: ApplicationFiled: April 19, 2021Publication date: June 22, 2023Inventors: Mohammad Aghaamoo, Ronald L. Biro, Kevin Day, Abraham P. Lee, Edwin Mendez, Pon Samuel, Justin Schares, Yue Yun, Braulio Cardenas Benitez
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Publication number: 20220290175Abstract: The subject invention provides novel plants that are not only resistant to 2,4-D, but also to pyridyloxyacetate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention “stacked” together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-12 (AryloxyAlkanoate Dioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.Type: ApplicationFiled: May 23, 2022Publication date: September 15, 2022Inventors: Terry R. WRIGHT, Justin M. LIRA, Terence Anthony WALSH, Donald MERLO, Jayakumar Pon SAMUEL, Gaofeng LIN
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Patent number: 11371055Abstract: The subject invention provides novel plants that are not only resistant to 2,4-D, but also to pyridyloxyacetate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention “stacked” together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-12 (AryloxyAlkanoate Dioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.Type: GrantFiled: March 24, 2017Date of Patent: June 28, 2022Assignee: Corteva Agriscience LLCInventors: Terry R. Wright, Justin M. Lira, Terence Anthony Walsh, Donald Merlo, Jayakumar Pon Samuel, Gaofeng Lin
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Patent number: 10214746Abstract: The present disclosure relates in part to a method for identifying a soybean germline transformant from a population of soybean transformants by incorporating a selection agent within rooting medium used in tissue culture during the soybean transformation process. The soybean germline transformants are selected from a population of soybean transformants which are comprised of a combination of non-germline and germline soybean transformants. The soybean non-germline transformants are identified and eliminated early in the transformation process. The soybean germline transformants are identified and selected for culturing into mature soybean plants. The method is readily applicable for screening and obtaining a soybean germline transformant at an early stage in the soybean transformation process.Type: GrantFiled: October 2, 2014Date of Patent: February 26, 2019Assignee: Dow AgroSciences LLCInventors: Sivarama Reddy Chennareddy, Dayakar Pareddy, Jayakumar Pon Samuel, Rodrigo Sarria-Milan, Toby Cicak
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Patent number: 10174331Abstract: Disclosed herein are methods and compositions for homology-independent targeted insertion of donor molecules into the genome of a cell.Type: GrantFiled: May 7, 2013Date of Patent: January 8, 2019Assignees: Sangamo Therapeutics, Inc., Dow AgroSciences LLCInventors: Gregory J. Cost, Fyodor Urnov, W. Michael Ainley, Joseph F. Petolino, Jayakumar Pon Samuel, Steven R. Webb, Lakshmi Sastry-Dent
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Patent number: 10167483Abstract: The subject invention provides novel plants that are not only resistant to 2,4-D, but also to pyridyloxyacetate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention “stacked” together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-12 (AryloxyAlkanoate Dioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.Type: GrantFiled: September 19, 2014Date of Patent: January 1, 2019Assignee: Dow AgroSciences LLCInventors: Terry R. Wright, Justin M. Lira, Terence Anthony Walsh, Donald Merlo, Jayakumar Pon Samuel, Gaofeng Lin
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Publication number: 20170306339Abstract: Provided are methods for introducing a molecule of interest into a plant cell comprising a cell wall. Methods are provided for genetically or otherwise modifying plants and for treating or preventing disease in plant cells comprising a cell wall.Type: ApplicationFiled: June 22, 2017Publication date: October 26, 2017Inventors: Jayakumar Pon Samuel, Frank G. Burroughs, Suraj K. Dixit, Mark W. Zettler
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Patent number: 9719108Abstract: Provided are methods for introducing a sequence-specific nuclease into a plant cell comprising a cell wall. Methods are provided for genetically or otherwise modifying plants and for treating or preventing disease in plant cells comprising a cell wall.Type: GrantFiled: September 22, 2015Date of Patent: August 1, 2017Assignee: Dow AgroSciences LLCInventors: Jayakumar Pon Samuel, Joseph F. Petolino, Narasimha Chary Samboju, Steven R. Webb, Kerrm Y. Yau
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Publication number: 20170211087Abstract: The subject invention provides novel plants that are not only resistant to 2,4-D, but also to pyridyloxyacetate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention “stacked” together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-12 (AryloxyAlkanoate Dioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.Type: ApplicationFiled: March 24, 2017Publication date: July 27, 2017Inventors: Terry R. WRIGHT, Justin M. LIRA, Terence Anthony WALSH, Donald MERLO, Jayakumar Pon SAMUEL, Gaofeng LIN
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Publication number: 20170022521Abstract: Provided are methods for introducing a sequence-specific nuclease into a plant cell comprising a cell wall. Methods are provided for genetically or otherwise modifying plants and for treating or preventing disease in plant cells comprising a cell wall.Type: ApplicationFiled: September 22, 2015Publication date: January 26, 2017Inventors: Jayakumar Pon Samuel, Joseph F. Petolino, Narasimha Chary Samboju, Steven R. Webb, Kerrm Y. Yau
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Publication number: 20170009214Abstract: The subject invention provides novel plants that are not only resistant to 2,4-D, but also to pyridyloxyacetate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention “stacked” together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-12 (AryloxyAlkanoate Dioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.Type: ApplicationFiled: September 19, 2014Publication date: January 12, 2017Inventors: Terry R. Wright, Justin M. Lira, Terence Anthony Walsh, Donald Merlo, Jayakumar Pon Samuel, Gaofeng Lin
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Publication number: 20170002369Abstract: Provided are methods for introducing a molecule of interest into a plant cell comprising a cell wall. Methods are provided for genetically or otherwise modifying plants and for treating or preventing disease in plant cells comprising a cell wall.Type: ApplicationFiled: September 21, 2016Publication date: January 5, 2017Inventors: Jayakumar Pon Samuel, Frank G. Burroughs, Suraj K. Dixit, Mark W. Zettler
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Patent number: 9493779Abstract: Methods and compositions for gene disruption, gene editing or gene stacking within a FAD2 loci by cleaving, in a site directed manner, a location in a FAD2 gene in a soybean cell, to generate a break in the FAD2 gene and then optionally integrating into the break a nucleic acid molecule of interest is disclosed.Type: GrantFiled: September 5, 2013Date of Patent: November 15, 2016Assignees: Dow AgroSciences LLC, Sangamo BioSciences, Inc.Inventors: William Michael Ainley, Steven R. Webb, Pon Samuel, Dmitry Y. Guschin, Jeffrey C. Miller, Lei Zhang
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Patent number: 9476057Abstract: Provided are methods for introducing a molecule of interest into a plant cell comprising a cell wall. Methods are provided for genetically or otherwise modifying plants and for treating or preventing disease in plant cells comprising a cell wall.Type: GrantFiled: May 12, 2014Date of Patent: October 25, 2016Assignee: Dow AgroSciences LLCInventors: Jayakumar Pon Samuel, Frank G. Burroughs, Suraj K. Dixit, Mark W. Zettler
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Publication number: 20150307889Abstract: Disclosed are methods for transformation of an androgenic-derived, haploid cell line with a site-specific nuclease. In some embodiments, the androgenic-derived, haploid cell line is a maize microspore-derived plant tissue culture. In addition, the disclosure provides a method for modifying, e.g., by mutating or targeting and integrating donor DNA into, a specific locus of a haploid or dihaploid tissue genome. The disclosure further provides methods for regenerating a whole plant from the haploid or dihaploid tissue that contains either the mutation at a specific genomic locus or a donor DNA integrated within a specific genomic locus may be obtained from the subject disclosure.Type: ApplicationFiled: April 24, 2015Publication date: October 29, 2015Inventors: Joseph F. Petolino, Tonya L. Strange, Jayakumar Pon Samuel, Ryan C. Blue, Matthew A. Simpson
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Publication number: 20150099648Abstract: The present disclosure relates in part to a method for identifying a soybean germline transformant from a population of soybean transformants by incorporating a selection agent within rooting medium used in tissue culture during the soybean transformation process. The soybean germline transformants are selected from a population of soybean transformants which are comprised of a combination of non-germline and germline soybean transformants. The soybean non-germline transformants are identified and eliminated early in the transformation process. The soybean germline transformants are identified and selected for culturing into mature soybean plants. The method is readily applicable for screening and obtaining a soybean germline transformant at an early stage in the soybean transformation process.Type: ApplicationFiled: October 2, 2014Publication date: April 9, 2015Inventors: Sivarama Reddy CHENNAREDDY, Dayakar PAREDDY, Jayakumar Pon SAMUEL, Rodrigo SARRIA-MILAN, Toby CICAK
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Publication number: 20150080218Abstract: The subject invention provides novel plants that are not only resistant to 2,4-D, but also to pyridyloxyacetate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention “stacked” together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-12 (AryloxyAlkanoate Dioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.Type: ApplicationFiled: September 19, 2014Publication date: March 19, 2015Inventors: Terry R. Wright, Justin M. Lira, Terence Anthony Walsh, Donald Merlo, Pon Samuel Jayakumar, Gaofeng Lin
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Publication number: 20140283225Abstract: The present disclosure relates in part to a method for identifying a soybean germline transformant from a population of soybean transformants which are comprised of a combination of soybean non-germline transformants and soybean germline transformants. The soybean non-germline transformants are identified and eliminated early in the transformation process. The soybean germline transformants are detected and selected for culturing into mature soybean plants. The method is readily applicable for screening and obtaining a soybean germline transformant at an early stage in the transformation process.Type: ApplicationFiled: March 14, 2014Publication date: September 18, 2014Applicant: Dow Agrosciences LLCInventors: Jayakumar Pon Samuel, Sivarama Reddy Chennareddy, Andy Bowling, John Whitteck, Tatyana Minnicks, Dayakar Pareddy, Kerrm Y. Yau, Kelley A. Smith
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Publication number: 20140242703Abstract: Provided are methods for introducing a molecule of interest into a plant cell comprising a cell wall. Methods are provided for genetically or otherwise modifying plants and for treating or preventing disease in plant cells comprising a cell wall.Type: ApplicationFiled: May 12, 2014Publication date: August 28, 2014Applicant: DOW AGROSCIENCES LLCInventors: Jayakumar Pon Samuel, Frank G. Burroughs, Suraj K. Dixit, Mark W. Zettler