Abstract: A fluidic coupling device includes a housing, and a piston, spring, and cap insertable in the housing. The spring includes a stack of spring washers and is compressible between the cap and the the piston. The cap is threadedly engageable with the housing and movable into contact with the spring. The device may be coupled to a component in a sealed manner by inserting a ferrule between the piston and the component, inserting a conduit through the housing and into the component, and threadedly engaging the housing with the component, thereby compressing the spring and translating the piston against the ferrule. The device may enable coupling to be done manually, with minimal variation in compressive loading. The piston and spring may desensitize the device to thermal cycling effects, reducing the need for retightening.

Abstract: A single-piece ferrule for a fitting for coupling a capillary to another component of a fluidic device, wherein the ferrule comprises a ferrule body, wherein the ferrule body has a lumen configured for receiving at least a part of the capillary, wherein the ferrule body has a tapering front part configured for forming a sealed connection with a housing of the fitting, wherein a back side of the tapering front part has an annular undercut.

Abstract: A fluidic coupling device includes a housing, and a piston, spring, and cap insertable in the housing. The spring includes a stack of spring washers and is compressible between the cap and the the piston. The cap is threadedly engageable with the housing and movable into contact with the spring. The device may be coupled to a component in a sealed manner by inserting a ferrule between the piston and the component, inserting a conduit through the housing and into the component, and threadedly engaging the housing with the component, thereby compressing the spring and translating the piston against the ferrule. The device may enable coupling to be done manually, with minimal variation in compressive loading. The piston and spring may desensitize the device to thermal cycling effects, reducing the need for retightening.

Abstract: A ferrule package includes a plurality of ferrules and a packaging device configured for containing the ferrules in a uniform orientation. A selected ferrule may be removed by moving an aperture into alignment with a receptacle containing the ferrule inserting an insert such as a tube into a bore of the ferrule, and removing the selected ferrule from the receptacle while the ferrule is on the insert. The ferrule may be removed without making contact with the ferrule.

Abstract: A single-piece ferrule for a fitting for coupling a capillary to another component of a fluidic device, wherein the ferrule comprises a ferrule body, wherein the ferrule body has a lumen configured for receiving at least a part of the capillary, wherein the ferrule body has a tapering front part configured for forming a sealed connection with a housing of the fitting, wherein a back side of the tapering front part has an annular undercut.

Abstract: An inlet liner is provided for use in an inlet assembly of a chromatograph system. The inlet liner has an elongate tube that extends along a longitudinal axis and defines a bore that extends along the longitudinal axis and has an inner bore surface. At least one projection extends from the inner bore surface into the bore. Chromatograph systems are provided including the exemplary inlet liner(s). Methods are also provided for analyzing a sample containing a matrix in a chromatograph system having an inlet assembly connected to a chromatograph column. The method includes positioning an exemplary inlet liner in the inlet assembly, flowing the sample through the inlet liner, and adhering a portion of the matrix to a projection surface of at least one projection of the inlet liner.

Abstract: An inlet liner is provided for use in an inlet assembly of a chromatograph system. The inlet liner has an elongate tube that extends along a longitudinal axis and defines a bore that extends along the longitudinal axis and has an inner bore surface. At least one projection extends from the inner bore surface into the bore. Chromatograph systems are provided including the exemplary inlet liner(s). Methods are also provided for analyzing a sample containing a matrix in a chromatograph system having an inlet assembly connected to a chromatograph column. The method includes positioning an exemplary inlet liner in the inlet assembly, flowing the sample through the inlet liner, and adhering a portion of the matrix to a projection surface of at least one projection of the inlet liner.