Patents by Inventor Ponnambalam R. Selvaganapathy

Ponnambalam R. Selvaganapathy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Single cell microinjection using flexible and compliant fluidic channels and electroosmotic dosage control
    Patent number: 8173415
    Abstract: A microinjection device for injecting a target cell with a reagent. The microinjection device includes a flexible substrate; a target supply channel formed in the flexible substrate for receiving the target cell; a reagent supply channel formed in the flexible substrate for receiving the reagent; a suction capillary mounted within a suction channel formed in the flexible substrate, the suction capillary providing suction to the target supply channel for immobilizing the target cell within the target supply channel; an injection needle mounted within a needle channel formed in the flexible substrate, the injection needle being movable between injected and un-injected positions by deforming at least a part of the flexible substrate; and a plurality of electrodes embedded in the flexible substrate, the plurality of electrodes creating a voltage potential across the injection needle to move the reagent into the target when the injection needle is in the injected position.
    Type: Grant
    Filed: October 9, 2009
    Date of Patent: May 8, 2012
    Assignee: McMaster University
    Inventors: Arash Noori, Ponnambalam R. Selvaganapathy
  • SINGLE CELL MICROINJECTION USING FLEXIBLE AND COMPLIANT FLUIDIC CHANNELS AND ELECTROOSMOTIC DOSAGE CONTROL
    Publication number: 20100093065
    Abstract: A microinjection device for injecting a target cell with a reagent. The microinjection device includes a flexible substrate; a target supply channel formed in the flexible substrate for receiving the target cell; a reagent supply channel formed in the flexible substrate for receiving the reagent; a suction capillary mounted within a suction channel formed in the flexible substrate, the suction capillary providing suction to the target supply channel for immobilizing the target cell within the target supply channel; an injection needle mounted within a needle channel formed in the flexible substrate, the injection needle being movable between injected and un-injected positions by deforming at least a part of the flexible substrate; and a plurality of electrodes embedded in the flexible substrate, the plurality of electrodes creating a voltage potential across the injection needle to move the reagent into the target when the injection needle is in the injected position.
    Type: Application
    Filed: October 9, 2009
    Publication date: April 15, 2010
    Inventors: Arash Noori, Ponnambalam R. Selvaganapathy