Patents by Inventor Potlapally Kumar

Potlapally Kumar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

Medical devices employing triazine compounds and compositions thereof

Publication number: 20070122444

Abstract: The present invention relates to methods, compounds, and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses, and is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention also relates to compounds that inhibit smooth muscle proliferation, for example, by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis. This invention also relates to medical devices, such as a stent, comprising a compound or composition of this invention disposed on or within the medical device.

Type: Application

Filed: August 30, 2006

Publication date: May 31, 2007

Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Sesha Alluri, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Rama Murali Krishna Reddy, Potlapally Kumar, Gaddam Reddy
Methods and compositions of novel triazine compounds

Publication number: 20070117795

Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.

Type: Application

Filed: August 28, 2006

Publication date: May 24, 2007

Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Rama Krishna Reddy, Sesha Alluri, Potlapally Kumar, Gaddam Reddy
Methods and compositions of novel triazine compounds

Publication number: 20070099874

Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.

Type: Application

Filed: March 26, 2003

Publication date: May 3, 2007

Applicant: Reddy US Therapeutics, Inc.

Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Rama Reddy, Sesha Alluri, Potlapally Kumar, Gaddam Reddy
Methods and compositions of novel triazine compounds

Publication number: 20070004729

Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.

Type: Application

Filed: June 20, 2006

Publication date: January 4, 2007

Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Rama Reddy, Sesha Alluri, Potlapally Kumar, Gaddam Reddy
Methods and compositions of novel triazine compounds

Publication number: 20060258641

Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.

Type: Application

Filed: May 25, 2006

Publication date: November 16, 2006

Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Rama Reddy, Sesha Alluri, Potlapally Kumar, Gaddam Reddy
Process for the preparation of optically pure isomers of 2-(4-hydroxy phenoxy)-2-methyl-butyric acid methyl ester

Publication number: 20060194980

Abstract: The invention provides a process for preparing R-(+)-2-(4-hydroxyphenoxy)-2-methyl-butyric acid methyl ester of the formula (1): Various embodiments and variants are provided. The invention also provides a process for preparing S-(?)-2-(4-hydroxyphenoxy)-2-methyl-butyric acid methyl ester of the formula (II) Various embodiments and variants are provided.

Type: Application

Filed: October 11, 2005

Publication date: August 31, 2006

Inventors: Potlapally Kumar, Velagala Reddy, Jangalgar Reddy, Gurram Madhaven, Sunil Singh
Methods and compositions of novel triazine compounds

Publication number: 20060172984

Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.

Type: Application

Filed: November 22, 2005

Publication date: August 3, 2006

Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Yeleswarapu Rao, Manojit Pal, Jangalgar Reddy, Velagala Venkata Rama Reddy, Sesha Alluri, Potlapally Kumar, Gaddam Reddy
Triazine compounds and their analogs, compositions, and methods

Publication number: 20050227983

Abstract: The present invention relates to triazine compounds and their analogs and derivatives, and methods and compositions comprising these compounds. The compounds and compositions of this invention are useful for, among other things, treating pathophysiological conditions arising from inflammatory responses, inhibiting or blocking glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells, inhibiting smooth muscle proliferation, treating vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis, and the like.

Type: Application

Filed: March 24, 2004

Publication date: October 13, 2005

Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Sesha Alluri, Velagala Venkata Krishna Reddy, Manojit Pal, Jangalgar Reddy, Koteswar Yeleswarapu, Gaddam Reddy, Potlapally Kumar
Medical devices employing triazine compounds and compositions thereof

Publication number: 20050137196

Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.

Type: Application

Filed: September 27, 2004

Publication date: June 23, 2005

Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Krishna Reddy, Bhatlapenumarthy Sesha Sridevi, Potlapally Kumar, Gaddam Reddy
Medical devices employing triazine compounds and compositions thereof

Publication number: 20050124619

Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.

Type: Application

Filed: September 27, 2004

Publication date: June 9, 2005

Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Krisha Reddy, Bhatlapenumarthy Sesha Sridevi, Potlapally Kumar, Gaddam Reddy
Medical devices employing triazine compounds and compositions thereof

Publication number: 20050113341

Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.

Type: Application

Filed: September 27, 2004

Publication date: May 26, 2005

Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Murali Krishna Reddy, Bhatlapenumarthy Sridevi, Potlapally Kumar, Gaddam Reddy