Abstract: The present invention relates inter alia to an apparatus for providing a coiled collagen carrier. An apparatus according to the invention preferably comprises a device for applying moisture to a collagen carrier prior to coiling of the collagen carrier and a coiling device. The coiling device preferably comprises rotatable gripping means for gripping the collagen carrier along an edge and coiling the collagen carrier, and a support device supporting the collagen carrier while being coiled. In another aspect, the invention relates to a production facility wherein an apparatus according to invention is arranged.

Abstract: The invention relates to a process for the preparation of a rolled compressed collagen carrier and a process for un-rolling said rolled compressed collagen carrier. Said rolled compressed collagen carrier is ready for use in minimally invasive surgery. The invention also relates to a rolled compressed collagen carrier for use in the prevention or treatment of injury associated with performing minimally invasive surgery.

Abstract: The present invention relates to a packaging for storing a form-stable coiled collagen carrier. The form-stable coiled collagen carrier comprises a collagen layer and a coating layer comprising thrombin and fibrinogen and having the shape of an elongated element with a number of windings of the collagen carrier about the longitudinal axis of the elongated element with at least one outer winding(s) being orientated so that the coating layer constitutes the outer surface of each of said outer winding(s). The packaging preferably comprises a container part having a compartment in which at least a part of the coiled collagen carrier is contained.

Abstract: For allowing an access to an eye during a rinsing process it is suggested to configure an eye opening device in such a way that the eye opening device comprises two wing-like spreading elements for pulling the upper eyelid and the lower eyelid of the eye apart so as to support the opening of the eye during a rinsing process, wherein two access gaps are formed laterally between the two wing-like spreading elements of the eye opening device.

Abstract: The present invention relates inter alia to an apparatus for providing a coiled collagen carrier. An apparatus according to the invention preferably comprises a device for applying moisture to a collagen carrier prior to coiling of the collagen carrier and a coiling device. The coiling device preferably comprises rotatable gripping means for gripping the collagen carrier along an edge and coiling the collagen carrier, and a support device supporting the collagen carrier while being coiled. In another aspect, the invention relates to a production facility wherein an apparatus according to invention is arranged.

Abstract: The present invention relates inter alia to an apparatus for providing a coiled collagen carrier. An apparatus according to the invention preferably comprises a device for applying moisture to a collagen carrier prior to coiling of the collagen carrier and a coiling device. The coiling device preferably comprises rotatable gripping means for gripping the collagen carrier along an edge and coiling the collagen carrier, and a support device supporting the collagen carrier while being coiled. In another aspect, the invention relates to a production facility wherein an apparatus according to invention is arranged.

Abstract: The invention relates to a process for the preparation of a rolled compressed collagen carrier and a process for un-rolling said rolled compressed collagen carrier. Said rolled compressed collagen carrier is ready for use in minimally invasive surgery. The invention also relates to a rolled compressed collagen carrier for use in the prevention or treatment of injury associated with performing minimally invasive surgery.

Abstract: The invention relates to a process for the preparation of a rolled compressed collagen carrier and a process for un-rolling said rolled compressed collagen carrier. Said rolled compressed collagen carrier is ready for use in minimally invasive surgery. The invention also relates to a rolled compressed collagen carrier for use in the prevention or treatment of injury associated with performing minimally invasive surgery.

Abstract: For allowing an access to an eye during a rinsing process it is suggested to configure an eye opening device in such a way that the eye opening device comprises two wing-like spreading elements for pulling the upper eyelid and the lower eyelid of the eye apart so as to support the opening of the eye during a rinsing process, wherein two access gaps are formed laterally between the two wing-like spreading elements of the eye opening device.

Abstract: An eye rinsing device for rinsing at least one eye is embodied as an attachable attachment, which can be connected to a container, wherein the attachment can be placed onto the eye of a person. The eye rinsing device is provided with at least one rinsing opening, which is directed towards the eye by means of which the washing of an eye is carried out in an improved manner. The attachment encompasses a device having wing-like spreading elements which pull the upper eyelid and the lower eyelid apart so as to support the opening of the eye during the rinsing process.

Abstract: A packaging unit for holding a plurality of articles, preferably disposable articles, such, as plasters, tissues, gauze, etc. The packaging unit comprises a holding member (2) comprising a first part (5) with at most fifteen spaced apart flaps (6), and a second part (7), the first and second parts being arranged oppositely each other. A plurality of articles are arranged and retained between the first and second parts in such a manner that an individual article can be removed from the packaging unit. The packaging unit is insertable in a dispenser (13) and may serve as a refill package. Furthermore, a dispenser for delivering disposable articles, the dispenser comprising a retaining part (14) for retaining a packaging unit and an opening (15) allowing a packaging unit to be inserted and allowing an individual article to be delivered. The opening is arranged in such a manner that an individual article may be delivered from the dispenser by pulling it in a substantially downwards direction.

Abstract: The present invention relates to a packaging for storing a form-stable coiled collagen carrier. The form-stable coiled collagen carrier comprises a collagen layer and a coating layer comprising thrombin and fibrinogen and having the shape of an elongated element with a number of windings of the collagen carrier about the longitudinal axis of the elongated element with at least one outer winding(s) being orientated so that the coating layer constitutes the outer surface of each of said outer winding(s). The packaging preferably comprises a container part having a compartment in which at least a part of the coiled collagen carrier is contained.

Abstract: The present invention relates inter alia to an apparatus for providing a coiled collagen carrier. An apparatus according to the invention preferably comprises a device for applying moisture to a collagen carrier prior to coiling of the collagen carrier and a coiling device. The coiling device preferably comprises rotatable gripping means for gripping the collagen carrier along an edge and coiling the collagen carrier, and a support device supporting the collagen carrier while being coiled. In another aspect, the invention relates to a production facility wherein an apparatus according to invention is arranged.

Abstract: The invention relates to a process for the preparation of a rolled compressed collagen carrier and a process for un-rolling said rolled compressed collagen carrier. Said rolled compressed collagen carrier is ready for use in minimally invasive surgery. The invention also relates to a rolled compressed collagen carrier for use in the prevention or treatment of injury associated with performing minimally invasive surgery.

Abstract: To create an eye rinsing device (100) for rinsing at least one eye (12), which is embodied as an attachable attachment (11), which can be connected to a container (10), wherein the attachment (11) can be placed onto the eye (12) of a person, and is provided with at least one rinsing opening (15), which is directed towards the eye (12), by means of which the washing of an eye is carried out in an improved manner, it is proposed for the attachment (11) to encompass a device comprising wing-like spreading elements (16, 17), which pull the upper eyelid (13) and the lower eyelid (14) apart, so as to support the opening of the eye (12) during the rinsing process.

Abstract: A packaging unit for holding a plurality of articles, preferably disposable articles, such, as plasters, tissues, gauze, etc. The packaging unit comprises a holding member (2) comprising a first part (5) with at most fifteen spaced apart flaps (6), and a second part (7), the first and second parts being arranged oppositely each other. A plurality of articles are arranged and retained between the first and second parts in such a manner that an individual article can be removed from the packaging unit. The packaging unit is insertable in a dispenser (13) and may serve as a refill package. Furthermore, a dispenser for delivering disposable articles, the dispenser comprising a retaining part (14) for retaining a packaging unit and an opening (15) allowing a packaging unit to be inserted and allowing an individual article to be delivered. The opening is arranged in such a manner that an individual article may be delivered from the dispenser by pulling it in a substantially downwards direction.

Abstract: It has been found that pharmaceutical compositions comprising water insoluble drugs can be manufactured and formulated in a manner ensuring fast dissolution in gastric fluid. Advantageously, the manufacturing process provides a significantly improved stability, thus resulting in compositions that may have a longer shelf life than conventionally formulated and processed drugs.

Abstract: A dry manufacturing process for the production of a pharmaceutical formulation of a benzimidazole and an alkaline substance is described. A tablet is compressed directly from a dry powder or a dry particulate matter avoiding any liquid or excipient conventionally used as a wet binder. The manufacturing process has the advantage of being simple and cost efficient. At the same time an expensive drying step is superfluous. The resulting pharmaceutical formulation has a good stability and a good dissolution profile.

Abstract: Novel controlled release pharmaceutical compositions for oral use containing midodrine and/or its active metabolite desglymidodrine. The novel compositions are designed to release midodrine and/or desglymidodrine after oral intake in a manner which enables absorption to take place in the gastrointestinal tract so that a relatively fast peak plasma concentration of the active metabolite desglymidodrine is obtained followed by a prolonged and relatively constant plasma concentration of desglymidodrine. The novel compositions may be designed for administration once or twice daily, i.e. a therapeutically effective concentration of desglymidodrine is maintained for a period of at least 10-16 hours followed by a wash out period of about 8-12 hours in order to avoid the well-known midodrine related side effect with respect to supine hypertension. The therapeutically effective concentration of desglymidodrine is regarded as a plasma concentration of desglymidodrine of at least about 3 ng/ml.