Patents by Inventor Poul Borrevang

Poul Borrevang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 2-imidazolines and use thereof
    Patent number: 5262430
    Abstract: The invention relates to novel substituted 2-imidazolines (I) having a lowering effect on blood glucose in mammals, to their preparation, to pharmaceutical compostions containing them and to their use.
    Type: Grant
    Filed: December 16, 1991
    Date of Patent: November 16, 1993
    Assignee: Novo Nordisk A/S
    Inventors: Poul Borrevang, Henrik S. Andersen
  • 2,3,4,5-tetrahydro-1H-3-benzazepines and CNS affecting use thereof
    Patent number: 4751222
    Abstract: Novel 2,3,4,5-tetrahydro-1H-3-benzazepines which in the 5-position have furyl, thienyl, pyridyl, or ring systems consisting of phenyl ortho condensed with a benzen, cyclohexan, cyclohexen, cyclopentan or cyclopenten ring wherein one of the carbon atoms may be exchanged with oxygen, sulphur or nitrogen, have interesting central nervous system and cardiovascular effects.
    Type: Grant
    Filed: April 21, 1986
    Date of Patent: June 14, 1988
    Assignee: Novo Industri A/S
    Inventors: Claus Braestrup, Peter H. Andersen, Poul Borrevang, Frederik C. Gr nvald, Louis B. Hansen, Rolf Hohlweg
  • Process for the production of penam and cephem derivatives
    Patent number: 4202817
    Abstract: A process for the preparation of penam and cephem derivatives by reacting a phosphite amide of a 6-aminopenicillanic acid or 7-aminocephalosporanic acid with an acyl halide in an aprotic solvent in the presence of a phosphite halide scavenger.
    Type: Grant
    Filed: September 18, 1978
    Date of Patent: May 13, 1980
    Assignee: Novo Industri A/S
    Inventors: Erling Guddal, Poul Borrevang
  • Process for the preparation of phosphorus derivatives of secondary ammonium salts of penam and cephem compounds
    Patent number: 4082745
    Abstract: An improvement in the conversion of penam and cephem compounds to secondary ammonium salts of phosphite amides thereof by reacting as follows: ##STR1## wherein --R, is the non-reacting balance of the penam or cephem compound and ##STR2## ARE NON-REACTING SUBSTITUENTS. Catalytic amounts of H--N< or the hydrogenhalide thereof may be present in the reaction medium.
    Type: Grant
    Filed: March 22, 1976
    Date of Patent: April 4, 1978
    Assignee: Novo Industri A/S
    Inventors: Poul Borrevang, Erling Guddal, Henning Borge Petersen, Peter Faarup, Jorgen Ilum Nielsen
  • Process for converting penicillin sulfoxides to the corresponding 3-desacetoxycephalosporins
    Patent number: 4051133
    Abstract: Conversion of penicillin sulfoxides to the corresponding 3-desacetoxycelphalosporins are carried out in high yield by heating, e.g. 80.degree.-130.degree. C, a solvent solution of the penicillin in the presence of a complex formed by a phosphite or phosphine amide with the salt of a strong acid and a nitrogenous base, e.g. alpha-picoline hydrobromide.One preferred amide is 2-piperidino-1,3,2-dioxaphospolane.
    Type: Grant
    Filed: January 2, 1976
    Date of Patent: September 27, 1977
    Assignee: Novo Industri A/S
    Inventors: Poul Borrevang, Henning Borge Petersen
  • Penicillin and cephalosporin intermediates
    Patent number: 3994883
    Abstract: Novel penicillin and cephalosporin intermediates for the synthesis of 6-APA or 7-aminocephem compounds involving formation of a 6 or 7 phosphite amido compound and the conversion of such compound to a desired 6-APA or 7-aminocephem compound.
    Type: Grant
    Filed: December 21, 1973
    Date of Patent: November 30, 1976
    Assignee: Novo Industri A/S
    Inventors: Poul Borrevang, Erling Guddal, Henning Borge Petersen, Peter Faarup, Jorgen Ilum Nielsen