Patents by Inventor Pouria Jandaghi

Pouria Jandaghi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pancreatic cancer therapy and diagnosis
    Patent number: 10874685
    Abstract: The present disclosure provides a novel method for treating pancreatic cancer and pancreatitis in which a combination of a dopamine receptor antagonist (pimozide, haloperidol, and/or L-741,626), 2-deoxy-D-glucose and atorvastatin are used, optionally in combination with gemcitabine.
    Type: Grant
    Filed: August 12, 2019
    Date of Patent: December 29, 2020
    Assignees: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY, DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTS
    Inventors: Pouria Jandaghi, Yasser Riaz Alhosseini, Daniel Scott Auld, Veena Sangwan
  • PANCREATIC CANCER THERAPY AND DIAGNOSIS
    Publication number: 20200030356
    Abstract: The present disclosure provides a novel method for treating pancreatic cancer and pancreatitis. The disclosure pertains to antagonists of dopamine receptors, that when combined with a glycolysis inhibitor, and a cholesterol lowering agent inhibit the growth of pancreatic cells.
    Type: Application
    Filed: August 12, 2019
    Publication date: January 30, 2020
    Inventors: Pouria JANDAGHI, Yasser RIAZ ALHOSSEINI, Daniel Scott AULD, Veena SANGWAN
  • Pancreatic cancer therapy and diagnosis
    Patent number: 10420757
    Abstract: The current disclosure relates to methods for treating pancreatic cancer or chronic pancreatitis in a subject comprising administering an antagonist of a dopamine receptor to the subject wherein the dopamine receptor is, in some specific cases dopamine receptor D2 (DRD2). The antagonist in some specific cases is an RNAi construct, an antibody, or a small molecule and in more specific cases pimozide or L-741,626. The disclosure also relates to diagnostic methods comprising the detection of the expression of DRD2 in pancreatic tissue and kits for doing the same.
    Type: Grant
    Filed: April 17, 2015
    Date of Patent: September 24, 2019
    Assignees: Deutsches Krebsforschungszentrum Stiftung des Öffentlichenrechts, The Royal Institution for the Advancement of Learning/McGill University
    Inventors: Pouria Jandaghi, Jörg Hoheisel, Yasser Riazalhosseini