Patents by Inventor Prabhakar Macharla

Prabhakar Macharla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR THE PREPARATION OF 5-[[[(2S)-2-AMINO-3-[4-(AMINOCARBONYL)-2,6-DIMETHYLPHENYL]-1-OXOPROPYL] [(1S)-1-(4-PHENYL-1H-IMIDAZOL-2-YL)ETHYL]AMINO] METHYL-2-METHOXYBENZOIC ACID AND ITS POLYMORPHS THEREOF
    Publication number: 20190177281
    Abstract: The present invention relates to an improved process for the preparation of 5-[[[(2S)-2-amino-3-[4-(aminocarbonyl)-2,6-dimethylphenyl]-1-oxopropyl][(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino]methyl]-2-methoxybenzoic acid compound of formula-1, and polymorphs thereof, the compound of formula-1 is further represented by the following structural formula:
    Type: Application
    Filed: May 2, 2017
    Publication date: June 13, 2019
    Inventors: Srinivasan Thirumalai RAJAN, Eswaraiah SAJJA, Rajeshwar Reddy SAGYAM, Prabhakar MACHARLA, Rajesham BOGE
  • Aprepitant polymorph mixtures
    Patent number: 8217039
    Abstract: Intimate mixtures of aprepitant crystalline Form I and crystalline Form II, having specific weight ratios of the forms.
    Type: Grant
    Filed: March 29, 2007
    Date of Patent: July 10, 2012
    Assignees: Dr. Reddy's Laboratories Ltd., Dr. Reddy's Laboratories, Inc.
    Inventors: Vijayavitthal Thippannachar Mathad, Pravinchandra Jayantilal Vankawala, Raviram Chandrasekhar Elati, Prabhakar Macharla, Srinivas Gangula, Naveen Kumar Kolla, Ravi Kumar Komareddy, Surya Narayana Devarkonda, Subbareddy Peddireddy
  • APREPITANT POLYMORPH MIXTURES
    Publication number: 20100298327
    Abstract: Intimate mixtures of aprepitant crystalline Form I and crystalline Form II, having specific Hweight ratios of the forms.
    Type: Application
    Filed: March 29, 2007
    Publication date: November 25, 2010
    Applicants: DR. REDDY'S LABORATORIES LTD., DR. REDDY'S LABORATORIES, INC.
    Inventors: Vijayavitthal Thippannachar Mathad, Pravinchandra Jayantilal Vankawala, Raviram Chandrasekhar Elati, Prabhakar Macharla, Srinivas Gangula, Naveen Kumar Kolla, Ravi Kumar Komareddy, Surya Narayana Devarkonda, Subbareddy Peddireddy
  • PROCESSES FOR PREPARING PIOGLITAZONE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS
    Publication number: 20090118514
    Abstract: An improved process for the preparation of pioglitazone and its pharmaceutically acceptable salts by reducing 5-[4-[2-(5-ethyl-2-pyridyl)ethoxy]benzilidene]-2,4-thiazolidinedione with sodium borohydride in presence of a cobalt ion and dimethyl glyoxime. More particularly the cobalt ion used is cobalt chloride hexahydrate, or, cobalt (II) nitrate hexahydrate in presence of mixture of DMF and water as solvents.
    Type: Application
    Filed: November 5, 2008
    Publication date: May 7, 2009
    Inventors: Raghupathi Reddy Anumula, Goverdhan Gilla, Lokeswara Rao Madivada, Prabhakar Macharla, Kavitha Charagondla
  • Synthesis of Atomoxetine Hydrochloride
    Publication number: 20080004470
    Abstract: (±)-Atomoxetine oxalate having crystalline Form II and a solid (±)-atomoxetine free base are useful in preparing atomoxetine hydrochloride.
    Type: Application
    Filed: September 27, 2005
    Publication date: January 3, 2008
    Inventors: Vijayavitthal Mathad, Mahesh Ghanta, Shanmugam Govindan, Prabhakar Macharla, Venu Nalivela