Patents by Inventor Prabhakar R. Sheth

Prabhakar R. Sheth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of manufacturing an antihypertensive, diuretic and antihypokalemic pharmaceutical composition with polyethylene glycol
    Patent number: 4793999
    Abstract: A novel method of manufacturing a novel effective antihypertensive, diuretic and antihypokalemic pharmaceutical composition in which a triamterene active pteridine, a hydrochlorothiazide active benzothiadiazide, and a filler are thoroughly mixed with a polyethylene glycol, applying heat to the melting point thereof when the mixture instantaneously fuses to form granules, while cooled, then the granules are formulated into effective dosage units.
    Type: Grant
    Filed: March 27, 1987
    Date of Patent: December 27, 1988
    Inventor: Prabhakar R. Sheth
  • Prevention of N-nitroso compound formation in vivo
    Patent number: 4681756
    Abstract: The effect of a controlled release, hydrodynamically balanced dosage formulation containing both an aqueous phase N-nitroso compound blocking agent and a lipid phase N-nitroso compound blocking agent in preventing the formation of nitrosamines and nitrosamides in the stomach is disclosed.
    Type: Grant
    Filed: June 26, 1986
    Date of Patent: July 21, 1987
    Assignee: Hoffman-La Roche Inc.
    Inventors: William J. Mergens, Harold L. Newmark, Prabhakar R. Sheth, Jacques L. Tossounian
  • Hydrodynamically balanced controlled release compositions containing L-dopa and a decarboxylase inhibitor
    Patent number: 4424235
    Abstract: Hydrodynamically balanced controlled release compositions for the preparation of pharmaceutical capsules or tablets which contain L-Dopa and a decarboxylase inhibitor and which provide superior blood levels of L-Dopa are disclosed.
    Type: Grant
    Filed: November 1, 1982
    Date of Patent: January 3, 1984
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Prabhakar R. Sheth, Jacques L. Tossounian
  • Novel sustained release tablet formulations
    Patent number: 4167558
    Abstract: A novel sustained release formulation for the preparation of tablets for oral administration is disclosed. The formulation is hydrodynamically balanced to be buoyant in gastric juice thereby remaining in the stomach for an extended period of time.
    Type: Grant
    Filed: November 6, 1978
    Date of Patent: September 11, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Prabhakar R. Sheth, Jacques L. Tossounian
  • Sustained release tablet formulations
    Patent number: 4140755
    Abstract: A novel sustained release formulation for the preparation of tablets for oral administration is disclosed. The formulation is hydrodynamically balanced to be buoyant in gastric juice thereby remaining in the stomach for an extended period of time.
    Type: Grant
    Filed: January 25, 1978
    Date of Patent: February 20, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Prabhakar R. Sheth, Jacques L. Tossounian
  • Sustained release pharmaceutical capsules
    Patent number: 4126672
    Abstract: Sustained release pharmaceutical capsules suitable for oral administration and particularly suitable for sustained release therapy with certain benzodiazepines, e.g. chlordiazepoxide and diazepam, are disclosed. The formulation contained in the disclosed capsules is hydrodynamically balanced to be buoyant in gastric fluid thereby remaining buoyant in the gastric fluid until substantially all of the medicament therein has been released.
    Type: Grant
    Filed: September 19, 1977
    Date of Patent: November 21, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Prabhakar R. Sheth, Jacques L. Tossounian