Patents by Inventor Prabhakaran Ramkishen

Prabhakaran Ramkishen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cholesterol biosynthesis pathway modulators and uses thereof
    Publication number: 20060222638
    Abstract: An isolated peptide comprising the amino acid sequence of SEQ ID NO: 2, or a variant, derivative and/or fragment thereof having the function of HMGCoA reductase inhibitor, phosphomevalonate inhibitor, reducing the accumulation of cholesterol in the cholesterol biosynthesis pathway and/or reducing the level of serum cholesterol. Also disclosed is a pharmaceutical composition comprising the peptide having sequence SEQ ID NO:2 or a variant, derivative and/or fragment thereof. Also disclosed is a method for treatment or prophylaxis of disorders characterised by the accumulation of cholesterol, its by-products and/or related lipid derived products, comprising administering to a subject in need at least one peptide comprising the amino acid sequence of SEQ ID NO: 2, or a variant, derivative and/or fragment thereof.
    Type: Application
    Filed: June 4, 2004
    Publication date: October 5, 2006
    Applicant: National University of Singapore
    Inventors: Kandiah Jeyaseelan, Arunmozhiarasi Armugam, Siaw Chai, Prabhakaran Ramkishen, Ponnampalam Gopalakrishnakone, Kwon Huat Tan