Abstract: Described herein are synthetic cyclic peptide mimetics comprising alternating D-amino acids and L-amino acids and amino acid derivatives, such as aza-amino acids and azasulfuryl-amino acids. Optionally, the cyclic peptide mimetics may be conjugated to another agent via a linker to form cyclic peptide mimetic conjugates. The cyclic peptide mimetics described herein may be used as diagnostic or therapeutic agents for diagnosis or treatment of amyloidogenic diseases.

Abstract: Among the various aspects of the present disclosure is the provision of treatments, monitoring treatment or progression, or methods for detecting utDNA in a subject having or suspected of having a urinary tract-associated cancer.

Abstract: Low-pass whole genome sequencing, as well as targeted hybrid-capture next-generation sequencing, were performed to detect both small mutations and genome-wide copy number alterations to more precisely detect MRD after physician's-choice neoadjuvant chemotherapy. A machine learning model using both cell-free DNA and pre-treatment clinical characteristics is disclosed. With this method, it was possible to significantly predict both progression-free and overall survival.

Abstract: A movable operator station is disclosed. The movable operator station includes a first base plate, a second base plate, and a first support unit. A multi-tier structure is slidably coupled to the first base plate and is slidable in “X” axis between first and second positions. The second base plate is slidably coupled to the first base plate and is slidable between third and fourth positions. The first support unit is slidably coupled to the second base plate and is slidable along the “X” axis. A set of linking members links the first multi-tier structure to the first support unit. The set of linking members extends or collapses based on a movement of the second base plate along the “Y” axis. The first support unit and the set of linking members form a second multi-tier structure when the second base plate is at the fourth position.

Abstract: A security system that provides an easy to read and understand alarm notification. In one example, if an alarm condition is detected by a particular sensor of a security system, the security system may be configured to display on a display of the security system and/or a mobile device a user-defined image object. Each image object may correspond to a user-defined region of a building space image, such as a floorplan.

Abstract: A security system that provides an easy to read and understand alarm notification. In one example, if an alarm condition is detected by a particular sensor of a security system, the security system may be configured to display on a display of the security system and/or a mobile device a user-defined image object. Each image object may correspond to a user-defined region of a building space image, such as a floorplan.

Abstract: Disclosed is, among other things, techniques to obtain information about client companies, staffing firms, and jobs, which may allow contractors to find the work they desire more efficiently.