Abstract: A user experience repository may contain base layouts and variant metadata for applications of an enterprise. An application design platform may receive, from a designer, an indication of a selected base layout for a selected application and interact with the designer to create a user experience variant (e.g., a page layout). The designer may then define an assignment rule for the user experience variant, the assignment rule including custom logic and multiple user parameters (e.g., a user role, country, language, etc.), and the system may store information about the user experience variant and assignment rule. An enterprise application service platform may determine that a user is accessing the selected application and evaluate the custom logic of the assignment rule based on user parameters of the user accessing the selected application. In accordance with the evaluation, the system may arrange to provide the appropriate user experience variant to the user.

Abstract: The present application is directed to a therapeutically useful monomer comprising a linker element and an E3 ubiquitin ligase binding moiety. The linker and the E3 ubiquitin ligase binding moiety are covalently coupled to each other either directly or through an optional connector moiety.

Abstract: The compounds of the present invention are represented by the following compounds having Formula (I): where the substituents R, R1-R5, k, m, n, and q are as defined herein. These compounds are used in the treatment of cancer, immunologic disorders, autoimmune disorders, neurodegenerative disorders, or inflammatory disorders, infectious disease, or for providing immunosuppression for transplanted organs or tissues.

Abstract: The compounds of the present invention are represented by the following compounds having Formula I: where the substituents R1, R4, L, M, X, Y, and s are as defined herein. The compounds of the present invention are also represented by the following compounds having Formula (Ia), Formula (Ib), or Formula (Ic): where the substituents R1-R4, Rx, Ry, X, Y, and s are as defined herein. These compounds are used in the treatment of cancer, immunologic disorders, autoimmune disorders, neurodegenerative disorders, or inflammatory disorders or for providing immunosuppression for transplanted organs or tissues.

Abstract: The compounds of the present invention are represented by the following compounds having Formula I: where the substituents R1, R4, L, M, X, Y, and s are as defined herein. The compounds of the present invention are also represented by the following compounds having Formula (Ia), Formula (Ib), or Formula (Ic): where the substituents R1-R4, Rx, Ry, X, Y, and s are as defined herein. These compounds are used in the treatment of cancer, immunologic disorders, autoimmune disorders, neurodegenerative disorders, or inflammatory disorders or for providing immunosuppression for transplanted organs or tissues.

Abstract: The compounds of the present invention are represented by the following compounds having Formula (I) where the substituents R, R1-R5, k, m, n, and q are as defined herein. These compounds are used in the treatment of cancer, immunologic disorders, autoimmune disorders, neurodegenerative disorders, or inflammatory disorders, infectious disease, or for providing immunosuppression for transplanted organs or tissues.

Abstract: The compounds of the present invention are represented by the following compounds having Formula (I): where the substituents R, R1-R5, k, m, n, and q are as defined herein. These compounds are used in the treatment of cancer, immunologic disorders, autoimmune disorders, neurodegenerative disorders, or inflammatory disorders, infectious disease, or for providing immunosuppression for transplanted organs or tissues.

Abstract: The compounds of the present invention are represented by the following compounds having Formula (I) where the substituents R, R1-R5, k, m, n, and q are as defined herein. These compounds are used in the treatment of cancer, immunologic disorders, autoimmune disorders, neurodegenerative disorders, or inflammatory disorders, infectious disease, or for providing immunosuppression for transplanted organs or tissues.

Abstract: The compounds of the present invention are represented by the following compounds having Formula (I) where the substituents R, R1-R5, k, m, n, and q are as defined herein. These compounds are used in the treatment of cancer, immunologic disorders, autoimmune disorders, neurodegenerative disorders, or inflammatory disorders, infectious disease, or for providing immunosuppression for transplanted organs or tissues.

Abstract: The compounds of the present invention are represented by the following compounds having Formula I, where the substituents R1, R4, L, M, X, Y, and s are as defined herein. The compounds of the present invention are also represented by the following compounds having Formula (Ia), Formula (Ib), or Formula (Ic), where the substituents R1-R4, RX, RY, X, Y, and s are as defined herein. These compounds are used in the treatment of cancer, immunologic disorders, autoimmune disorders, neurodegenerative disorders, or inflammatory disorders or for providing immunosuppression for transplanted organs or tissues.

Abstract: The present invention provides a gallium-containing composition for coating/impregnating a device or device surface to prevent biofilm growth formation. The present invention also provides a method of preventing or inhibiting biofilm growth formation. The present invention also provides methods for killing established biofilms.

Abstract: The present system includes a system, method and device for inferring connectivity between unconnected network segments. In operation, unconnected network segments are identified. Configuration data related to the unconnected network segments may be examined to facilitate inferring configuration data for an external network connected between the unconnected network segments. The inferred configuration data may be rendered, such as exported or visualized. The inferred configuration data may be related to a communication protocol and/or may be related to network bandwidth. The examined configuration data may be captured directly from one or more of the unconnected network segments and/or may be retrieved from a configuration data file, such as a network configuration model.

Abstract: All of the transit services that each device is expected to provide are determined and contrasted with the transit configuration of each device. Because the transit configuration of each device may be state-dependent, the service items within each application service are processed in sequential order. Sequences of service items are associated with connection groups, and each of the routes associated with each connection group is determined based on the sequential order of the service items. The configuration of each device along each route is processed to determine the services that will be permitted or denied, based on its current configuration. Each desired transit service item is compared to the transit configuration provided by each device to identify any inconsistencies and/or violations.

Abstract: A security policy database identifies the intended security policies within a network, a traffic generator provides test traffic that is configured to test each defined security policy, and a simulator simulates the propagation of this traffic on a model of the network. The model of the network includes the configuration data associated with each device, and thus, if devices are properly configured to enforce the intended security policies, the success/failure of the simulated test traffic will conform to the intended permit/deny policy of each connection. Differences between the simulated message propagation and the intended security policies are reported to the user, and diagnostic tools are provided to facilitate identification of the device configuration data that accounts for the observed difference. Additionally, if a network's current security policy is unknown, test traffic is generated to reveal the actual policy in effect, to construct a baseline intended security policy.

Abstract: The present system includes a system, method and device for inferring connectivity between unconnected network segments. In operation, unconnected network segments are identified. Configuration data related to the unconnected network segments may be examined to facilitate inferring configuration data for an external network connected between the unconnected network segments. The inferred configuration data may be rendered, such as exported or visualized. The inferred configuration data may be related to a communication protocol and/or may be related to network bandwidth. The examined configuration data may be captured directly from one or more of the unconnected network segments and/or may be retrieved from a configuration data file, such as a network configuration model.

Abstract: The present system includes a system, method and device for inferring connectivity between network devices across a third party network. Configuration data related to the network devices is examined and configuration data about the network is inferred. The inferred configuration data may be related to a communication protocol, network bandwidth, and the like. A model representing the network is then created to indicate inferred interfaces and connections through the external network between network devices. The representation may be rendered in various forms, such as a display or data exported to another system. Various studies may also be performed using the model, such as traffic, routing, or planning studies.

Abstract: Network survivability is quantified in such a way that failure cases can be compared and ranked against each other in terms of the severity of their impact on the various performance measures associated with the network. The degradation in network performance caused by each failure is quantified based on user-defined sets of thresholds of degradation severity for each performance measure. Each failure is simulated using a model of the network, and a degradation vector is determined for each simulated failure. A comparison function is defined to map the degradation vectors into an ordered set, and this ordered set is used to create an ordered list of network failures, in order of the network degradation caused by each failure.

Abstract: A simulator simulates routing system protocols to build routing tables corresponding to a modeled network, and a comparator compares the routing tables in the actual network to these simulator-created routing tables. Because the modeled system represents a fault-free version of the actual system, and assuming that the modeled routing system protocols are representative of the algorithms used in the actual routers, these simulator-produced routing tables can represent steady-state routing tables that should be present in the routers of the actual network at steady state. By querying each router in the actual network for its routing table and comparing each routing table to the corresponding simulator-produced routing table, any differences from the steady state can be identified.

Abstract: The embodiments relate to modeling wireless communications in a network. In wireless communications, the nodes share one or more wireless communication channels. When a node has data to transmit, it must contend with the other nodes for access to the wireless communication channel. In the embodiments, the model is configured to simulate the throughput effects of contention including delays caused by retransmissions due to interference and collisions, listen-and-backoff, unavailability of time slots, etc. The occurrence of failed/dropped transmissions due to buffer overflows, excessive retransmission attempts, and unintended collisions are modeled as well. In addition, the embodiments may simulate the effect of mobility by the nodes and the effect of the location of the nodes relative to each other.

Abstract: A contextual and semantic analysis of network entities facilitates a mapping and comparison of the entities between network models. The system includes a plurality of refine handler and match handler pairs that use rules that are specific to the type of network entities being analyzed. The refine handler analyzes the network model to identify the entities for which its rules apply, and the match handler processes these identified entities to establish a pairing between corresponding entities in each model. A sequence of refine-match processes are applied to the network models, typically in accordance with a hierarchy of rules until each entity is identified as a matched, added, or removed entity. A difference handler processes the identified pairings to provide a difference analysis that facilitates a meaningful interpretation of the configuration changes, and a user interface provides an interactive environment to view the differences from different perspectives.