Abstract: A caliper pig for detecting geometrical deformation of a pipeline is disclosed. The caliper pig includes a body and a first sensor arm assembly. The first sensor arm assembly includes a primary caliper sensor ring adapted to be mounted on the body. Further, the first sensor arm assembly includes a plurality of sensor arms adapted circumferentially distributed on the primary caliper sensor ring. Each of the plurality of sensor arms includes a sensing arm adapted to be in contact with an internal surface of the pipeline and a pair of magnets adapted to rotate along the sensing arm. Each of the plurality of sensor arms includes a sensing unit configured to detect a change in magnetic field based on the movement of the sensing arm. The sensing unit is configured to generate an output indicative of an angle of deflection of the sensing arm while traversing on the internal surface of the pipeline.

Abstract: A caliper pig for detecting geometrical deformation of a pipeline is disclosed. The caliper pig includes a body and a first sensor arm assembly. The first sensor arm assembly includes a primary caliper sensor ring adapted to be mounted on the body. Further, the first sensor arm assembly includes a plurality of sensor arms adapted circumferentially distributed on the primary caliper sensor ring. Each of the plurality of sensor arms includes a sensing arm adapted to be in contact with an internal surface of the pipeline and a pair of magnets adapted to rotate along the sensing arm. Each of the plurality of sensor arms includes a sensing unit configured to detect a change in magnetic field based on the movement of the sensing arm. The sensing unit is configured to generate an output indicative of an angle of deflection of the sensing arm while traversing on the internal surface of the pipeline.

Abstract: The present disclosure relates to pharmaceutical salts and polymorphic forms of forms of pyrimidine derivatives that have inhibitory activities against mutant epidermal growth factor receptor (EGFR). The present disclosure further relates to the processes for the preparation of the pyrimidine derivatives and to the pharmaceutical salts and the polymorphic forms of the pyrimidine derivatives.

Abstract: In one embodiment, a method includes accessing a notification to be sent to a user, where the notification has a context. The method also includes sending a request to a history service for historical notification data associated with the user with respect to the context of the notification and a ranking of the notification where the ranking indicates a probability of the user interacting with the notification. The method also includes receiving the historical notification data and the ranking from the history service. Moreover, the method also includes determining a delivery policy to apply to the notification based at least in part on the context of the notification, the historical notification data, and the ranking. Furthermore, the method also includes applying the delivery policy to the notification to be sent to the user.

Abstract: In one embodiment, a method includes accessing a notification to be sent to a user, where the notification has a context. The method also includes sending a request to a history service for historical notification data associated with the user with respect to the context of the notification and a ranking of the notification where the ranking indicates a probability of the user interacting with the notification. The method also includes receiving the historical notification data and the ranking from the history service. Moreover, the method also includes determining a delivery policy to apply to the notification based at least in part on the context of the notification, the historical notification data, and the ranking. Furthermore, the method also includes applying the delivery policy to the notification to be sent to the user.

Abstract: In one embodiment, a method includes one or more computing devices accessing a notification to be sent to a user, where the notification has a context. The method also includes one or more computing devices sending a request to a history service for historical notification data associated with the user with respect to the context of the notification and a ranking of the notification where the ranking indicates a probability of the user interacting with the notification. The method also includes one or more computing devices receiving the historical notification data and the ranking from the history service. Moreover, the method also includes one or more computing devices determining a notification policy to apply to the notification based at least in part on the context of the notification, the historical notification data, and the ranking. Furthermore, the method also includes one or more computing devices applying the notification policy to the notification to be sent to the user.

Abstract: In one embodiment, a method includes one or more computing devices accessing a notification to be sent to a user, where the notification has a context. The method also includes one or more computing devices sending a request to a history service for historical notification data associated with the user with respect to the context of the notification and a ranking of the notification where the ranking indicates a probability of the user interacting with the notification. The method also includes one or more computing devices receiving the historical notification data and the ranking from the history service. Moreover, the method also includes one or more computing devices determining a delivery policy to apply to the notification based at least in part on the context of the notification, the historical notification data, and the ranking. Furthermore, the method also includes one or more computing devices applying the delivery policy to the notification to be sent to the user.

Abstract: In one embodiment, a method includes one or more computing devices accessing a notification to be sent to a user, where the notification has a context. The method also includes one or more computing devices sending a request to a history service for historical notification data associated with the user with respect to the context of the notification and a ranking of the notification where the ranking indicates a probability of the user interacting with the notification. The method also includes one or more computing devices receiving the historical notification data and the ranking from the history service. Moreover, the method also includes one or more computing devices determining a delivery policy to apply to the notification based at least in part on the context of the notification, the historical notification data, and the ranking Furthermore, the method also includes one or more computing devices applying the delivery policy to the notification to be sent to the user.

Abstract: In one embodiment, a method includes one or more computing devices accessing a notification to be sent to a user, where the notification has a context. The method also includes one or more computing devices sending a request to a history service for historical notification data associated with the user with respect to the context of the notification and a ranking of the notification where the ranking indicates a probability of the user interacting with the notification. The method also includes one or more computing devices receiving the historical notification data and the ranking from the history service. Moreover, the method also includes one or more computing devices determining a notification policy to apply to the notification based at least in part on the context of the notification, the historical notification data, and the ranking. Furthermore, the method also includes one or more computing devices applying the notification policy to the notification to be sent to the user.

Abstract: A process for the preparation of prostaglandin compounds having the formula (I): wherein A is selected from the group consisting of C1–C6 alkyl groups; C7–C16 aralkyl groups wherein an aryl portion thereof is unsubstituted or substituted with one to three substituents selected from the group consisting of C1–C6 alkyl groups, halo and CF3; and (CH2)nOR? wherein n is an integer from 1 to 3 and R? represents a C6–C10 aryl group which is unsubstituted or substituted with one to three substituents selected from the group consisting of C1–C6 alkyl groups, halo and CF3; B is selected from OR? and NHR? wherein R? is C1–C6 alkyl groups; and represents a double bond or a single bond, is disclosed. Novel intermediates are also disclosed.

Abstract: A process for the preparation of prostaglandin compounds having the formula (I): wherein A is selected from the group consisting of C1–C6 alkyl groups; C7–C16 aralkyl groups wherein an aryl portion thereof is unsubstituted or substituted with one to three substituents selected from the group consisting of C1–C6 alkyl groups, halo and CF3; and (CH2)nOR? wherein n is an integer from 1 to 3 and R? represents a C6–C10 aryl group which is unsubstituted or substituted with one to three substituents selected from the group consisting of C1–C6 alkyl groups, halo and CF3; B is selected from OR? and NHR? wherein R? is C1–C6 alkyl groups; and represents a double bond or a single bond, is disclosed. Novel intermediates are also disclosed.

Abstract: A process for the preparation of prostaglandin compounds having the formula (I): wherein A is selected from the group consisting of C1–C6 alkyl groups; C7–C16 aralkyl groups wherein an aryl portion thereof is unsubstituted or substituted with one to three substituents selected from the group consisting of C1–C6 alkyl groups, halo and CF3; and (CH2)nOR? wherein n is an integer from 1 to 3 and R? represents a C6–C10 aryl group which is unsubstituted or substituted with one to three substituents selected from the group consisting of C1–C6 alkyl groups, halo and CF3; B is selected from OR? and NHR? wherein R? is C1–C6 alkyl groups; and represents a double bond or a single bond, is disclosed. Novel intermediates are also disclosed.