Patents by Inventor Pradeep Kumar Yadav

Pradeep Kumar Yadav has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MICRORNA-541-3P AS A THERAPEUTIC AGENT AS WELL AS ZNF101 AND CASZ1 AS THERAPEUTIC TARGETS TO LOWER PLASMA LDL-C, INCREASE PLASMA HDL-C, AND REDUCE ATHEROSCLEROSIS
    Publication number: 20240401048
    Abstract: Provided are compositions and methods for lowering plasma LDL-C, increasing plasma HDL-C, and reducing atherosclerosis. The methods include administering to an individual in need miRNA-541-3P or a modified version thereof, or an agent other than the miRNA-541-3P or the modified version thereof that inhibits the function or expression of ZNF101 or CASZ1, or a combination thereof. Performing a method also decreases expression of apoB increases expression of apoA1 is increased.
    Type: Application
    Filed: June 5, 2024
    Publication date: December 5, 2024
    Inventors: Abulaish Ansari, Pradeep Kumar Yadav, M. Mahmood Hussain
  • NOVEL EFFICACIOUS MICRORNA-30C ANALOGS REDUCE APOLIPOPROTEIN B SECRETION IN HUMAN LIVER CELLS
    Publication number: 20230407302
    Abstract: Provided are potent miR-30c analogs that can be delivered to hepatoma cells without the aid of viral vectors and lipid emulsions. The miR-30c analogs contain an unmodified active sense strand and a modified passenger strand to enhance the stability and uptake of miR-30c by hepatoma cells. The miR-30c analogs are for use in treatment of hyperlipidemias and cardiovascular diseases.
    Type: Application
    Filed: February 6, 2023
    Publication date: December 21, 2023
    Inventors: Mahmood Hussain, Jia Sheng, Pradeep Kumar Yadav, Phensinee Haruehanroengra