Patents by Inventor Pradip M. Pathare

Pradip M. Pathare has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Water soluble vitamin B.sub.12 receptor modulating agents and methods related thereto
    Patent number: 6083926
    Abstract: Vitamin B.sub.12 receptor modulating agents capable of modulating cell surface receptors by affecting the cell surface receptor trafficking pathway are disclosed. The vitamin B.sub.12 receptor modulating agents are comprised of a covalently bound rerouting moiety and targeting moiety linked by a water-solublizing linker.
    Type: Grant
    Filed: November 23, 1998
    Date of Patent: July 4, 2000
    Assignees: The University of Washington, Receptagen Corporation
    Inventors: A. Charles Morgan, Jr., D. Scott Wilbur, Pradip M. Pathare
  • Water soluble vitamin B.sub.12 receptor modulating agents and methods related thereto
    Patent number: 5840712
    Abstract: Vitamin B.sub.12 receptor modulating agents capable of modulating cell surface receptors by affecting the cell surface receptor trafficking pathway are disclosed. The vitamin B.sub.12 receptor modulating agents are comprised of a covalently bound rerouting moiety and targeting moiety linked by a water-solublizing linker.
    Type: Grant
    Filed: October 19, 1995
    Date of Patent: November 24, 1998
    Assignees: Receptagen Corporation, University of WA
    Inventors: A. Charles Morgan, Jr., D. Scott Wilbur, Pradip M. Pathare
  • Biotinylated cobalamins
    Patent number: 5739287
    Abstract: A biotinylated cobalamin, formed from a vitamin B.sub.12 molecule coupled to a biotin molecule, is disclosed. In a preferred embodiment, the vitamin B.sub.12 molecule is cyanocobalamin. The biotin molecule can also be coupled to a rerouting moiety, optionally through a biotin binding protein such as avidin or streptavidin. The biotinylated cobalamin binds to a cell surface receptor, is invaginated, and once internalized affects the receptor trafficking pathway.
    Type: Grant
    Filed: March 16, 1995
    Date of Patent: April 14, 1998
    Assignees: University of Washington, Receptagen Corp.
    Inventors: D. Scott Wilbur, Pradip M. Pathare, A. Charles Morgan, Jr.