Patents by Inventor Pradman Qasba

Pradman Qasba has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Catalytic domains of beta(1,4)-galactosyltransferase I having altered metal ion specificity
    Patent number: 8703459
    Abstract: Disclosed are mutants of galactosyltransferases that can catalyze formation of oligosaccharides in the presence of magnesium; mutants of galactosyltransferases having altered donor and acceptor specificity which can catalyze formation of oligosaccharides in the presence of magnesium; methods and compositions that can be used to synthesize oligosaccharides; methods for increasing the immunogenicity of an antigen; and methods to stabilize platelets.
    Type: Grant
    Filed: December 6, 2004
    Date of Patent: April 22, 2014
    Assignee: The United States of America, as represented by the Secretary, Department of Health & Human Services
    Inventors: Pradman Qasba, Elizabeth Boeggeman, Boopathy Ramakrishnan
  • Catalytic domains of beta(1,4)-galactosyl transferase i having altered donor and acceptor specificities, domains that promote in vitro protein folding, and methods for their use
    Publication number: 20090233345
    Abstract: Disclosed are methods and compositions that can be used to synthesize oligosaccharides; mutants of galactosyltransferases having altered donor and acceptor specificity; methods for increasing the immunogenicity of an antigen; and polypeptide stem regions that can be used to promote in vitro folding of polypeptides, such as the catalytic domain from a galactosyltransferase.
    Type: Application
    Filed: January 13, 2009
    Publication date: September 17, 2009
    Applicant: Govt. of the US, as represented by the secretary, Dept. of Health and Human Services
    Inventors: Pradman Qasba, Boopathy Ramakrishnan
  • Catalytic domains of ?(1,4)-galactosyltransferase I having altered donor and acceptor specificities, domains that promote in vitro protein folding, and methods for their use
    Patent number: 7482133
    Abstract: Disclosed are methods and compositions that can be used to synthesize oligosaccharides; mutants of galactosyltransferases having altered donor and acceptor specificity; methods for increasing the immunogenicity of an antigen; and polypeptide stem regions that can be used to promote in vitro folding of polypeptides, such as the catalytic domain from a galactosyltransferase.
    Type: Grant
    Filed: July 8, 2005
    Date of Patent: January 27, 2009
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Pradman Qasba, Boopathy Ramakrishnan
  • Catalytic Domains Of Beta(1,4)-Galactosyltransferase I Having Altered Metal Ion Specificity
    Publication number: 20080199905
    Abstract: Disclosed are mutants of galactosyltransferases that can catalyze formation of oligosaccharides in the presence of magnesium; mutants of galactosyltransferases having altered donor and acceptor specificity which can catalyze formation of oligosaccharides in the presence of magnesium; methods and compositions that can be used to synthesize oligosaccharides; methods for increasing the immunogenicity of an antigen; and methods to stabilize platelets.
    Type: Application
    Filed: December 6, 2004
    Publication date: August 21, 2008
    Applicant: Goverment of the US, as represented by the Secretary, Department of Health and Human Services
    Inventors: Pradman Qasba, Elizabeth Boeggeman, Boopathy Ramakrishnan
  • Targeted Delivery System for Bioactive Agents
    Publication number: 20070258986
    Abstract: In accordance with the present invention, compounds, compositions and methods are provided that allow for the administration of a bioactive agent to an organism, including a human or an animal. The present invention can be used to treat or prevent a disease and/or disorder with a bioactive agent, or can be used to safely vaccinate a human or animal against a bioactive agent. The invention can also be used as a method for the delivery of bioactive agents for the treatment or prevention of a disease and/or a disorder, particularly targeted delivery of bioactive agents through the administration of glycoconjugates containing a bioactive agent bound to a targeting compound through a modified saccharide residue.
    Type: Application
    Filed: November 18, 2004
    Publication date: November 8, 2007
    Applicants: Govt of the US, as respresented by the secretary, Department of Health and Human Services
    Inventors: Pradman Qasba, Boopathy Ramakrishnan
  • Catalytic domains of beta(1,4)-galactosyltransferase I having altered donor and acceptor specificities, domains that promote in vitro protein folding, and methods for their use
    Publication number: 20060084162
    Abstract: Disclosed are methods and compositions that can be used to synthesize oligosaccharides; mutants of galactosyltransferases having altered donor and acceptor specificity; methods for increasing the immunogenicity of an antigen; and polypeptide stem regions that can be used to promote in vitro folding of polypeptides, such as the catalytic domain from a galactosyltransferase.
    Type: Application
    Filed: July 8, 2005
    Publication date: April 20, 2006
    Inventors: Pradman Qasba, Boopathy Ramakrishnan