Abstract: Systems and assemblies for performing point-of-care, fluidic assays having self-contained, portable fluidic assay systems or assemblies. A housing comprises an assaying assembly, an inspiration actuator, and an expulsion actuator. The inspiration and expulsion actuators may include one-way valves. The assaying assembly is configured to provide a visual indicator in response to being contacted by one or more target analytes within a fluid-assay sample mixture. The fluidic assay assembly has a reciprocal plunger disposed therewithin and, in some embodiments, the plunger has a resilient member to bias the plunger in one direction. Movement of the plunger in a first direction implements an inspiration stroke for drawing the assay sample such that it contacts the fluid from the fluid chamber and continued movement of the plunger implements an expulsion stroke for expelling the fluid-assay sample mixture through the outlet opening to the receptacle of the assaying assembly.

Abstract: Devices, systems, and methods for species and/or strain specific identification and assessment of susceptibility of microorganisms based on the response of sensors in a colorimetric sensor array to metabolic products of the microorganism. An exemplary method according to an embodiment of the present disclosure can include culturing a sample that contains microorganisms. The sample can be in a medium which is exposed to a colorimetric sensor array. A test substance can be introduced to the sample. The method can assess a susceptibility of the microorganisms to the test substance based on a change in at least one sensor in the colorimetric sensor array. Sensors in the colorimetric sensor array can change in response to volatile organic compounds produced by the microorganisms after addition of the test sub stance.

Abstract: The invention relates to point-of-care fluidic assays. In particular, the invention provides systems and assemblies for performing point-of-care, fluidic assays—preferably involving self-contained, portable fluidic assay systems or assemblies.

Abstract: Technical solutions are described for debugging a computer program product. An example computer-implemented method includes receiving an identifier of a portion of code from a first module of the computer program product, wherein the portion of code contains a defect. The method further includes displaying a list of execution scenarios that invoke the portion of code from the first module. The method further includes, in response to receipt of a selection of a first execution scenario from the list of execution scenarios, executing the computer program product according to the first execution scenario.

Abstract: Devices, systems, and methods for species and/or strain specific identification and assessment of susceptibility of microorganisms based on the response of sensors in a colorimetric sensor array to metabolic products of the microorganism. An exemplary method according to an embodiment of the present disclosure can include culturing a sample that contains microorganisms. The sample can be in a medium which is exposed to a colorimetric sensor array. A test substance can be introduced to the sample. The method can assess a susceptibility of the microorganisms to the test substance based on a change in at least one sensor in the colorimetric sensor array. Sensors in the colorimetric sensor array can change in response to volatile organic compounds produced by the microorganisms after addition of the test substance.

Abstract: Technical solutions are described for debugging a computer program product. An example computer-implemented method includes receiving an identifier of a portion of code from a first module of the computer program product, wherein the portion of code contains a defect. The method further includes displaying a list of execution scenarios that invoke the portion of code from the first module. The method further includes, in response to receipt of a selection of a first execution scenario from the list of execution scenarios, executing the computer program product according to the first execution scenario.