Patents by Inventor Prakash G. Jagtap

Prakash G. Jagtap has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR TREATMENT OF PREECLAMPSIA AND CANCER
    Publication number: 20250074877
    Abstract: Provided herein, in various embodiments, are compounds of general formula I: for use in the treatment of preeclampsia and preeclampsia associated conditions eclampsia, haemorrhagic stroke, haemolysis, elevated liver enzymes and low platelet count (HELLP) syndrome, placental abruption, renal failure and pulmonary oedema. Also described in embodiments herein are compounds of general formula II or general formula III for use in the prevention of cancer.
    Type: Application
    Filed: August 28, 2024
    Publication date: March 6, 2025
    Inventors: Prakash G. Jagtap, Kanneganti Murthy, Garry J. Southan
  • Substituted ideno[1,2-c]isoquinoline derivatives and methods of use thereof
    Publication number: 20030096833
    Abstract: The invention provides a novel class of substituted indeno[1,2-c]isoquinoline derivatives. Pharmaceutical compositions and methods of making and using the compounds, are also described.
    Type: Application
    Filed: August 31, 2001
    Publication date: May 22, 2003
    Inventors: Prakash G. Jagtap, Erkan Baloglu, John H. van Duzer, Csaba Szabo, Andrew L. Salzman
  • 2-Aroyl-4-acyl paclitaxel (taxol) analogs
    Publication number: 20030036661
    Abstract: 2-debenzoyl-4-deacetyl paclitaxel, antineoplastic analogs thereof and intermediates are taught, as well as the formation of the compound, analogs and intermediates. The compound, analogs and intermediates may be used to form pharmaceutical compositions having anti-neoplastic activity. Further, the compound, analogs and intermediates may be used to treat cancer when applied in an effective amount by means such as a pharmaceutical composition.
    Type: Application
    Filed: August 2, 2002
    Publication date: February 20, 2003
    Applicant: Bristol-Myers Squibb Company
    Inventors: David George Ian Kingston, Mahendra Devichand Chordia, Prakash G. Jagtap, John Kadow
  • 2-aroyl-4-acyl paclitaxel (Taxol) analogs
    Patent number: 6476242
    Abstract: 2-debenzoyl-4-deacetyl paclitaxel, antineoplastic analogs thereof and intermediates are taught, as well as the formation of the compound, analogs and intermediates. The compound, analogs and intermediates may be used to form pharmaceutical compositions having anti-neoplastic activity. Further, the compound, analogs and intermediates may be used to treat cancer when applied in an effective amount by means such as a pharmaceutical composition.
    Type: Grant
    Filed: December 30, 1998
    Date of Patent: November 5, 2002
    Assignees: Bristol-Myers Squibb Company, Virginia Tech Intellectual Properties, Inc.
    Inventors: David George Ian Kingston, Mahendra Devichand Chordia, Prakash G. Jagtap, John Kadow
  • Methods for preparing 1-deoxy paclitaxels
    Patent number: 5739359
    Abstract: The present invention provides methods for making a novel class of 1-deoxy paclitaxel derivatives. These derivatives include 1-deoxy paclitaxel. The derivatives of the present invention are potent cytotoxic agents.
    Type: Grant
    Filed: April 14, 1997
    Date of Patent: April 14, 1998
    Assignee: Virginia Tech Intellectual Properties, Inc.
    Inventors: David G. I. Kingston, Mahendra D. Chordia, Prakash G. Jagtap