Patents by Inventor Prakash Gouda Avaji

Prakash Gouda Avaji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cationic polyphosphazene compound, polyphosphazenes-drug conjugate compound and method for preparing same
    Patent number: 11912829
    Abstract: The present invention relates to a new class of cationic linear polyphosphazenes bearing as side groups a hydrophilic poly(ethylene glycol) and a spacer group selected from the group consisting of lysine, oligopeptides containing lysine, amino-ethanol, amino-propanol, amino-butanol, amino-pentanol and amino-hexanol, and the polyphosphazene-drug conjugates comprising hydrophobic anticancer drugs by covalent bonding and the preparation methods thereof. The present polyphosphazene-drug conjugates exhibit outstanding tumor selectivity and low toxicity.
    Type: Grant
    Filed: November 1, 2021
    Date of Patent: February 27, 2024
    Assignee: CNPHARM CO., LTD.
    Inventors: Youn Soo Sohn, Yong Joo Jun, Prakash Gouda Avaji
  • NOVEL CATIONIC POLYPHOSPHAZENE COMPOUND, POLYPHOSPHAZENES-DRUG CONJUGATE COMPOUND AND METHOD FOR PREPARING SAME
    Publication number: 20220064384
    Abstract: The present invention relates to a new class of cationic linear polyphosphazenes bearing as side groups a hydrophilic poly(ethylene glycol) and a spacer group selected from the group consisting of lysine, oligopeptides containing lysine, amino-ethanol, amino-propanol, amino-butanol, amino-pentanol and amino-hexanol, and the polyphosphazene-drug conjugates comprising hydrophobic anticancer drugs by covalent bonding and the preparation methods thereof. The present polyphosphazene-drug conjugates exhibit outstanding tumor selectivity and low toxicity.
    Type: Application
    Filed: November 1, 2021
    Publication date: March 3, 2022
    Inventors: Youn Soo Sohn, Yong Joo Jun, Prakash Gouda Avaji
  • Cationic polyphosphazene compound, polyphosphazenes-drug conjugate compound and method for preparing same
    Patent number: 11180615
    Abstract: The present invention relates to a new class of cationic linear polyphosphazenes bearing as side groups a hydrophilic poly(ethylene glycol) and a spacer group selected from the group consisting of lysine, oligopeptides containing lysine, amino-ethanol, amino-propanol, amino-butanol, amino-pentanol and amino-hexanol, and the polyphosphazene-drug conjugates comprising hydrophobic anticancer drugs by covalent bonding and the preparation methods thereof. The present polyphosphazene-drug conjugates exhibit outstanding tumor selectivity and low toxicity.
    Type: Grant
    Filed: February 11, 2020
    Date of Patent: November 23, 2021
    Assignee: CNPHARM CO. LTD.
    Inventors: Youn Soo Sohn, Yong Joo Jun, Prakash Gouda Avaji
  • CATIONIC POLYPHOSPHAZENE COMPOUND, POLYPHOSPHAZENES-DRUG CONJUGATE COMPOUND AND METHOD FOR PREPARING SAME
    Publication number: 20200262981
    Abstract: The present invention relates to a new class of cationic linear polyphosphazenes bearing as side groups a hydrophilic poly(ethylene glycol) and a spacer group selected from the group consisting of lysine, oligopeptides containing lysine, amino-ethanol, amino-propanol, amino-butanol, amino-pentanol and amino-hexanol, and the polyphosphazene-drug conjugates comprising hydrophobic anticancer drugs by covalent bonding and the preparation methods thereof. The present polyphosphazene-drug conjugates exhibit outstanding tumor selectivity and low toxicity.
    Type: Application
    Filed: February 11, 2020
    Publication date: August 20, 2020
    Inventors: Youn Soo Sohn, Yong Joo Jun, Prakash Gouda Avaji
  • Cationic polyphosphazene compound, polyphosphazenes-drug conjugate compound and method for preparing same
    Patent number: 10590243
    Abstract: The present invention relates to a new class of cationic linear polyphosphazenes bearing as side groups a hydrophilic poly(ethylene glycol) and a spacer group selected from the group consisting of lysine, oligopeptides containing lysine, amino-ethanol, amino-propanol, amino-butanol, amino-pentanol and amino-hexanol, and the polyphosphazene-drug conjugates comprising hydrophobic anticancer drugs by covalent bonding and the preparation methods thereof. The present polyphosphazene-drug conjugates exhibit outstanding tumor selectivity and low toxicity.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: March 17, 2020
    Assignee: CNPHARM CO., LTD.
    Inventors: Youn Soo Sohn, Yong Joo Jun, Prakash Gouda Avaji
  • Cationic polyphosphazene compound, polyphosphazenes-drug conjugate compound and method for preparing same
    Patent number: 10584214
    Abstract: The present invention relates to a new class of cationic linear polyphosphazenes bearing as side groups a hydrophilic poly(ethylene glycol) and a spacer group selected from the group consisting of lysine, oligopeptides containing lysine, amino-ethanol, amino-propanol, amino-butanol, amino-pentanol and amino-hexanol, and the polyphosphazene-drug conjugates comprising hydrophobic anticancer drugs by covalent bonding and the preparation methods thereof. The present polyphosphazene-drug conjugates exhibit outstanding tumor selectivity and low toxicity.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: March 10, 2020
    Assignee: CNPHARM CO., LTD.
    Inventors: Youn Soo Sohn, Yong Joo Jun, Prakash Gouda Avaji
  • NOVEL CATIONIC POLYPHOSPHAZENE COMPOUND, POLYPHOSPHAZENES-DRUG CONJUGATE COMPOUND AND METHOD FOR PREPARING SAME
    Publication number: 20190284346
    Abstract: The present invention relates to a new class of cationic linear polyphosphazenes bearing as side groups a hydrophilic poly(ethylene glycol) and a spacer group selected from the group consisting of lysine, oligopeptides containing lysine, amino-ethanol, amino-propanol, amino-butanol, amino-pentanol and amino-hexanol, and the polyphosphazene-drug conjugates comprising hydrophobic anticancer drugs by covalent bonding and the preparation methods thereof The present polyphosphazene-drug conjugates exhibit outstanding tumor selectivity and low toxicity.
    Type: Application
    Filed: June 3, 2019
    Publication date: September 19, 2019
    Inventors: Youn Soo Sohn, Yong Joo Jun, Prakash Gouda Avaji
  • NOVEL CATIONIC POLYPHOSPHAZENE COMPOUND, POLYPHOSPHAZENES-DRUG CONJUGATE COMPOUND AND METHOD FOR PREPARING SAME
    Publication number: 20190284345
    Abstract: The present invention relates to a new class of cationic linear polyphosphazenes bearing as side groups a hydrophilic poly(ethylene glycol) and a spacer group selected from the group consisting of lysine, oligopeptides containing lysine, amino-ethanol, amino-propanol, amino-butanol, amino-pentanol and amino-hexanol, and the polyphosphazene-drug conjugates comprising hydrophobic anticancer drugs by covalent bonding and the preparation methods thereof. The present polyphosphazene-drug conjugates exhibit outstanding tumor selectivity and low toxicity.
    Type: Application
    Filed: June 3, 2019
    Publication date: September 19, 2019
    Inventors: Youn Soo Sohn, Yong Joo Jun, Prakash Gouda Avaji
  • Cationic polyphosphazene compound, polyphosphazenes-drug conjugate compound and method for preparing same
    Patent number: 10336867
    Abstract: The present invention relates to a new class of cationic linear polyphosphazenes bearing as side groups a hydrophilic poly(ethylene glycol) and a spacer group selected from the group consisting of lysine, oligopeptides containing lysine, amino-ethanol, amino-propanol, amino-butanol, amino-pentanol and amino-hexanol, and the polyphosphazene-drug conjugates comprising hydrophobic anticancer drugs by covalent bonding and the preparation methods thereof. The present polyphosphazene-drug conjugates exhibit outstanding tumor selectivity and low toxicity.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: July 2, 2019
    Assignee: CNPHARM CO., LTD
    Inventors: Youn Soo Sohn, Yong Joo Jun, Prakash Gouda Avaji
  • NOVEL CATIONIC POLYPHOSPHAZENE COMPOUND, POLYPHOSPHAZENES-DRUG CONJUGATE COMPOUND AND METHOD FOR PREPARING SAME
    Publication number: 20170037193
    Abstract: The present invention relates to a new class of cationic linear polyphosphazenes bearing as side groups a hydrophilic poly(ethylene glycol) and a spacer group selected from the group consisting of lysine, oligopeptides containing lysine, amino-ethanol, amino-propanol, amino-butanol, amino-pentanol and amino-hexanol, and the polyphosphazene-drug conjugates comprising hydrophobic anticancer drugs by covalent bonding and the preparation methods thereof. The present polyphosphazene-drug conjugates exhibit outstanding tumor selectivity and low toxicity.
    Type: Application
    Filed: March 13, 2015
    Publication date: February 9, 2017
    Inventors: Youn Soo Sohn, Yong Joo Jun, Prakash Gouda Avaji