Abstract: The present invention relates to an inhaler mouthpiece device for use as an accessory aid for metered dose inhalers and spacers used along with such inhalers. The device removably attachable to the metered dose inhaler simplifies and assists a patient's inhaling effort to advance an inhaled medication into lungs of the patient.

Abstract: A tinnitus treatment device can include an ultrasonic signal generator; an amplifier coupled to the ultrasonic signal generator; and an ultrasonic emitter coupled to an audio generating apparatus configured to output an audio modulated ultrasonic carrier signal into the air; wherein parameters of the tinnitus treatment device are configured to deliver tinnitus masking audio content.

Abstract: An improved metered dose inhaler may be provided. The improved inhaler may have a mouthpiece designed for improved medicine delivery. The mouthpiece may extend from a cap of the inhaler, which may be removable or molded to the body of the inhaler.

Abstract: The present invention is related to asphalt and asphalt-mineral compositions including at least one cationic organosilicon compound selected from a group consisting of: Y3-aSi(R1a)R2N+R3R4R5X?, Y3-aSi(R1a)R2P+R3R4R5X?, Y3-aSi(R1a)R2ZX?; or mixtures thereof, wherein in each formula Y is independently selected from a group consisting of OR, O(CH2CH2O)nH, (CH3OCH2CH2O), and (CH3CH2OCH2CH2O); a has a value selected from 0, 1 or 2; n is a value from 1 to 10; R is C1-C4 alkyl; R1 is either methyl or ethyl; R2 is C1-C4 alkylene group; R3, R4 and R5 are each independently selected from a group consisting of C1-C22 alkyl wherein at least one such group has more than 8 C-atoms, —CH2C6H5, —CH2CH2OH, —CH2OH and —(CH2)yNHC(O)R6 wherein y has a value of from 2 to 10 and R6 is a C1-C12 perfluoroalkyl radical; X is chloride, bromide, fluoride, iodide, acetate or tosylate; and Z is pyridinium ring of formula C5H5N+.

Abstract: The present invention is related to asphalt and asphalt-mineral compositions including at least one cationic organosilicon compound selected from a group consisting of: Y3-aSi(R1a)R2N+R3R4R5X?, Y3-aSi(R1a)R2P+R3R4R5X?, Y3-aSi(R1a)R2ZX?; or mixtures thereof, wherein in each formula Y is independently selected from a group consisting of OR, O(CH2CH2O)nH, (CH3OCH2CH2O), and (CH3CH2OCH2CH2O); a has a value selected from 0, 1 or 2; n is a value from 1 to 10; R is C1-C4 alkyl; R1 is either methyl or ethyl; R2 is C1-C4 alkylene group; R3, R4 and R5 are each independently selected from a group consisting of C1-C22 alkyl wherein at least one such group has more than 8 C-atoms, —CH2C6H5, —CH2CH2OH, —CH2OH and —(CH2)yNHC(O)R6 wherein y has a value of from 2 to 10 and R6 is a C1-C12 perfluoroalkyl radical; X is chloride, bromide, fluoride, iodide, acetate or tosylate; and Z is pyridinium ring of formula C5H5N+.

Abstract: The present invention is related to asphalt and asphalt-mineral compositions including at least one cationic organosilicon compound selected from a group consisting of: Y3-aSi(R1a)R2N+R3R4R5X?, Y3-aSi(R1a)R2P+R3R4R5X?, Y3-aSi(R1a)R2ZX?; or mixtures thereof, wherein in each formula Y is independently selected from a group consisting of OR, O(CH2CH2O)nH, (CH3OCH2CH2O), and (CH3CH2OCH2CH2O); a has a value selected from 0, 1 or 2; n is a value from 1 to 10; R is C1-C4 alkyl; R1 is either methyl or ethyl; R2 is C1-C4 alkylene group; R3, R4 and R5 are each independently selected from a group consisting of C1-C22 alkyl wherein at least one such group has more than 8 C-atoms, —CH2C6H5, —CH2CH2OH, —CH2OH and —(CH2)yNHC(O)R6 wherein y has a value of from 2 to 10 and R6 is a C1-C12 perfluoroalkyl radical; X is chloride, bromide, fluoride, iodide, acetate or tosylate; and Z is pyridinium ring of formula C5H5N+.

Abstract: The present invention is related to asphalt and asphalt-mineral compositions including at least one cationic organosilicon compound selected from a group consisting of: Y3-aSi(R1a)R2N+R3R4R5X?, Y3-aSi(R1a)R2P+R3R4R5X?, Y3-aSi(R1a)R2ZX?; or mixtures thereof, wherein in each formula Y is independently selected from a group consisting of OR, O(CH2CH2O)nH, (CH3OCH2CH2O), and (CH3CH2OCH2CH2O); a has a value selected from 0, 1 or 2; n is a value from 1 to 10; R is C1-C4 alkyl; R1 is either methyl or ethyl; R2 is C1-C4 alkylene group; R3, R4 and R5 are each independently selected from a group consisting of C1-C22 alkyl wherein at least one such group has more than 8 C-atoms, —CH2C6H5, —CH2CH2OH, —CH2OH and —(CH2)yNHC(O)R6 wherein y has a value of from 2 to 10 and R6 is a C1-C12 perfluoroalkyl radical; X is chloride, bromide, fluoride, iodide, acetate or tosylate; and Z is pyridinium ring of formula C5H5N+.