Abstract: A hybrid edge termination structure and method of forming the same. The hybrid edge termination structure in accordance with the invention is based on a junction termination extension (JTE) architecture, but includes an additional Layer of guard ring (GR) structures to further implement the implantation of dopants into the structure. The hybrid edge termination structure of the invention has a three-Layer structure, with a top Layer and a bottom Layer each having a constant dopant concentration in the lateral direction, and a middle Layer consisting of a plurality of spatially defined alternating regions that exhibit the electrical properties of either the top or bottom layer. By including the second layer, a discretized varying charge profile can be obtained that approximates the varying charge profile obtained using tapered edge termination but with easier manufacturing and lower cost.

Abstract: The present invention provides a wound inducible expression construct and a method of its preparation. The invention provides a methods for isolation of an early wound inducible promoter that is activated within 5 minutes of any form of wounding (mechanical or biological) and a process of making transgenic plants in which expression of GUS/Insecticidal protein is regulated by Promoter (I.D.1) in a wound inducible manner for local expression of a chimeric gene used in this method and plants obtained thereby, and to the process for obtaining resistance to insect feeding.

Abstract: The invention relates to inhibitors of EZH2 for use in the treatment of cancers characterised by expression of mutated histone H3 having a mutation of amino acid number 27. The invention also relates to methods for predicting the efficacy of treatment of a cancer with an inhibitor of EZH2 by determining whether the cancer cells contain a gene encoding p16INK4A, wherein the presence of a gene encoding p16INK4A is indicative of efficacy of treatment of the cancer with an inhibitor of EZH2.

Abstract: The present invention provides a wound inducible expression construct and a method of its preparation. The invention provides a methods for isolation of an early wound inducible promoter that is activated within 5 minutes of any form of wounding (mechanical or biological) and a process of making transgenic plants in which expression of GUS/Insecticidal protein is regulated by Promoter (I.D.1) in a wound inducible manner for local expression of a chimeric gene used in this method and plants obtained thereby, and to the process for obtaining resistance to insect feeding.

Abstract: In a channel zapping though multiple channels, each channel select identifies a new packet stream channel and the video coding standard of the channel is identified. Based on the video coding standard an optimal input buffer delay is identified, a packet stream for the new channel delayed by the optimal input buffer delay, and decoded by a decoding process according to video coding standard. Optionally, based on the video coding standard an optimal an optimal decoding processing delay is identified and the decoding applies an associated processing delay.

Abstract: A method of video encoding comprising receiving an image, selecting a macroblock in the image, determining a best intra encoding mode for the macroblock, determining a pixel direction from the determined best encoding intra mode, and selecting a pixel decimation pattern according to the determined pixel direction.

Abstract: The present invention generally relates to various nucleases and uses thereof, and in some cases, to the UPF0054 protein superfamily. Members of the UPF0054 protein superfamily, such as the E. coli protein YbeY, may possess RNase activity and may be involved in certain important cellular processes. Disruption of YbeY activity can lead to increased sensitivity to antibiotics. Accordingly, certain embodiments of the invention are directed to systems and methods for screening target compounds for activity against UPF0054 superfamily proteins. In some embodiments, the screening method allows to target compositions to be determined that show selective activity against UPF0054 superfamily proteins. Other embodiments of the invention provide for nucleases capable of site-specific cleavage of nucleic acids.