Patents by Inventor Pramila A. Bhatia

Pramila A. Bhatia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-substituted-furylalkenyl hydroxamic acid and N-hydroxyurea compounds having lipoxygenase inhibitory activity
    Patent number: 5169854
    Abstract: Compounds useful in inhibiting the biosynthesis of leukotrienes have the structure ##STR1## where M is hydrogen, a pharmaceutically acceptable cation, or a metabolically cleavable group, R.sup.4 is alkyl, cycloalkyl or --NR.sup.5 R.sup.6, where R.sup.5 and R.sup.6 are hydrogen, alkyl, cycloalkyl or alkanoyl, where A is a valence bond or is a straight or branched divalent alkylene group of from one to twelve carbon atoms, R.sup.2 and R.sup.3 are independently selected from hydrogen, straight or branched alkyl of from one to twelve carbon atoms, halogen, or trifluoroalkyl, and R.sup.1 is selected from phenoxy, phenylthio, 2-, 3-, or 4-pyridyloxy, 1 or 2-naphthyloxy, or 2,4,5, or 8-quinolyloxy, all optionally substituted with alkyl, haloalkyl, alkoxy, hydroxy or halogen.
    Type: Grant
    Filed: February 26, 1992
    Date of Patent: December 8, 1992
    Assignee: Abbott Laboratories
    Inventors: Dee W. Brooks, Andrew O. Stewart, Pramila Bhatia, Richard A. Craig
  • Triazinone lipoxygenase compounds
    Patent number: 4970210
    Abstract: Pyridazinone, triazinone and oxapyridazinone compounds which are useful in inhibiting lipoxygenase enzymes, particularly 5-lipoxygenase.
    Type: Grant
    Filed: June 28, 1988
    Date of Patent: November 13, 1990
    Assignee: Abbott Laboratories
    Inventors: Dee W. Brooks, Anwer Basha, Bruce P. Gunn, Pramila A. Bhatia