Patents by Inventor Pramod BHASME

Pramod BHASME has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for inhibiting formation of biofilms
    Patent number: 11950594
    Abstract: The present disclosure discloses a method for inhibiting formation of a biofilm of bacteria. Specifically, the method may include treating the bacteria with an effective amount of a coumarin-chalcone compound. While inhibiting the formation of the biofilm of the bacteria, the effective amount of the coumarin-chalcone compound may reduce virulences of the bacteria and enhance a susceptibility of the bacteria to an antibiotic when applied in combination with the antibiotic. The present disclosure further discloses a composition including an effective amount of the coumarin-chalcone compound. The composition may be used to inhibit the formation of the biofilm of bacteria. The composition may also include an antibiotic, a minimal inhibitory concentration and a minimal biofilm eliminate concentration of which are reduced when the composition is used.
    Type: Grant
    Filed: November 12, 2021
    Date of Patent: April 9, 2024
    Assignee: INSTITUTE OF MICROBIOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Luyan Ma, Qing Wei, Pramod Bhasme, Di Wang
  • METHODS AND COMPOSITIONS FOR INHIBITING FORMATION OF BIOFILMS
    Publication number: 20220167614
    Abstract: The present disclosure discloses a method for inhibiting formation of a biofilm of bacteria. Specifically, the method may include treating the bacteria with an effective amount of a coumarin-chalcone compound. While inhibiting the formation of the biofilm of the bacteria, the effective amount of the coumarin-chalcone compound may reduce virulences of the bacteria and enhance a susceptibility of the bacteria to an antibiotic when applied in combination with the antibiotic. The present disclosure further discloses a composition including an effective amount of the coumarin-chalcone compound. The composition may be used to inhibit the formation of the biofilm of bacteria. The composition may also include an antibiotic, a minimal inhibitory concentration and a minimal biofilm eliminate concentration of which are reduced when the composition is used.
    Type: Application
    Filed: November 12, 2021
    Publication date: June 2, 2022
    Applicant: INSTITUTE OF MICROBIOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Luyan MA, Qing WEI, Pramod BHASME, Di WANG